Cellular and molecular signaling towards T cell immunological self-tolerance

Keywords

TCR

regulatory T cells

immunological self-tolerance

CTLA-4

IL-2

CD45

AbbreviationsAICD

antigen-induced cell death

APC

antigen presenting cell

cSMAC

central supramolecular activation cluster

MHC

major histocompatibility complex

PD-1

programmed cell death protein 1

pTreg

peripheral Treg cell

TGF

transforming growth factor

tTreg

thymic-derived Treg cell

© 2024 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.

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