Head and neck cancers: reporting indications and results of hadrontherapy of a dual beam facility

Orlandi E, Barcellini A, Vischioni B, Fiore MR, Vitolo V, Iannalfi A, Bonora M, Chalaszczyk A, Ingargiola R, Riva G, Ronchi S, Valvo F, Fossati P, Ciocca M, Mirandola A, Molinelli S, Pella A, Baroni G, Pullia MG, Facoetti A, Orecchia R, Licitra L, Vago G, Rossi S. The Role of Carbon Ion Therapy in the Changing Oncology Landscape-A Narrative Review of the Literature and the Decade of Carbon Ion Experience at the Italian National Center for Oncological Hadrontherapy. Cancers (Basel). 2023;15(20):5068. https://doi.org/10.3390/cancers15205068.

Article  CAS  PubMed  Google Scholar 

Tinganelli W, Durante M. Carbon Ion Radiobiology. Cancers (Basel). 2020;12(10):3022. https://doi.org/10.3390/cancers12103022.

Article  CAS  PubMed  Google Scholar 

Loap P, Vischioni B, Bonora M, Ingargiola R, Ronchi S, Vitolo V, Barcellini A, Goanta L, De Marzi L, Dendale R, Pacelli R, Locati L, Calugaru V, Mammar H, Cavalieri S, Kirova Y, Orlandi E. Biological Rationale and Clinical Evidence of Carbon Ion Radiation Therapy for Adenoid Cystic Carcinoma: A Narrative Review. Front Oncol. 2021;30(11):789079. https://doi.org/10.3389/fonc.2021.789079.

Article  CAS  Google Scholar 

Barcellini A, Vitolo V, Facoetti A, Fossati P, Preda L, Fiore MR, Vischioni B, Iannalfi A, Bonora M, Ronchi S, D’Ippolito E, Petrucci R, Viselner G, Ciocca M, Valvo F, Orecchia R. Feasibility of Carbon Ion Radiotherapy in the Treatment of Gynecological Melanoma. In Vivo. 2009;33(2):473–6. https://doi.org/10.21873/invivo.11497.

Article  CAS  Google Scholar 

Jensen AD, Poulakis M, Nikoghosyan AV, Welzel T, Uhl M, Federspil PA, Freier K, Krauss J, Höss A, Haberer T, Jäkel O, Münter MW, Schulz-Ertner D, Huber PE, Debus J. High-LET radiotherapy for adenoid cystic carcinoma of the head and neck: 15 years’ experience with raster-scanned carbon ion therapy. Radiother Oncol. 2016;118(2):272–80. https://doi.org/10.1016/j.radonc.2015.05.010.

Article  PubMed  Google Scholar 

Locati LD, Ferrarotto R, Licitra L, Benazzo M, Preda L, Farina D, Gatta G, Lombardi D, Nicolai P, Vander Poorten V, Chua MLK, Vischioni B, Sanguineti G, Morbini P, Fonseca I, Sozzi D, Merlotti A, Orlandi E. Current management and future challenges in salivary glands cancer. Front Oncol. 2023;19(13):1264287. https://doi.org/10.3389/fonc.2023.1264287.

Article  CAS  Google Scholar 

Orlandi E, Iacovelli NA, Bonora M, Cavallo A, Fossati P. Salivary Gland: Photon beam and particle radiotherapy: Present and future. Oral Oncol. 2016;60:146–56. https://doi.org/10.1016/j.oraloncology.2016.06.019.

Article  PubMed  Google Scholar 

Mendenhall WM, Morris CG, Amdur RJ, Werning JW, Hinerman RW, Villaret DB. Radiotherapy alone or combined with surgery for adenoid cystic carcinoma of the head and neck. Head Neck. 2004;26(2):154–62. https://doi.org/10.1002/hed.10380.

Article  PubMed  Google Scholar 

Laramore GE, Krall JM, Griffin TW, Duncan W, Richter MP, Saroja KR, Maor MH, Davis LW. Neutron versus photon irradiation for unresectable salivary gland tumors: final report of an RTOG-MRC randomized clinical trial. Radiation Therapy Oncology Group, Medical Research Council. Int J Radiat Oncol Biol Phys. 1993;27(2):235–40. https://doi.org/10.1016/0360-3016(93)90233-l.

Article  CAS  PubMed  Google Scholar 

Sulaiman NS, Demizu Y, Koto M, Saitoh JI, Suefuji H, Tsuji H, Ohno T, Shioyama Y, Okimoto T, Daimon T, Nemoto K, Nakano T, Kamada T, Japan Carbon-Ion Radiation Oncology Study Group. Multicenter Study of Carbon-Ion Radiation Therapy for Adenoid Cystic Carcinoma of the Head and Neck: Subanalysis of the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS) Study (1402 HN). Int J Radiat Oncol Biol Phys. 2018;100(3):639–46. https://doi.org/10.1016/j.ijrobp.2017.11.010.

Article  Google Scholar 

Iannalfi A, D’Ippolito E, Riva G, Molinelli S, Gandini S, Viselner G, Fiore MR, Vischioni B, Vitolo V, Bonora M, Ronchi S, Petrucci R, Barcellini A, Mirandola A, Russo S, Vai A, Mastella E, Magro G, Maestri D, Ciocca M, Preda L, Valvo F, Orecchia R. Proton and carbon ion radiotherapy in skull base chordomas: a prospective study based on a dual particle and a patient-customized treatment strategy. Neuro Oncol. 2020;22(9):1348–58. https://doi.org/10.1093/neuonc/noaa067. Erratum. In: Neuro Oncol. 2022 Aug 1;24(8):1402–1403.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Molinelli S, Bonora M, Magro G, Casale S, Dale JE, Fossati P, Hasegawa A, Mirandola A, Ronchi S, Russo S, Preda L, Valvo F, Orecchia R, Ciocca M, Vischioni B. RBE-weighted dose in carbon ion therapy for ACC patients: Impact of the RBE model translation on treatment outcomes. Radiother Oncol. 2019;141:227–33. https://doi.org/10.1016/j.radonc.2019.08.022.

Article  CAS  PubMed  Google Scholar 

Vischioni B, Bonora M, Ronchi S, Ingargiola R, Camarda AM, Molinelli S, Imparato S, Fiorino F, Rancati T, Ciocca M, Orlandi E. OC-0110 Head and neck adenoid cystic carcinoma treated with raster scanning carbon ion radiotherapy at CNAO. Radiother Oncol. 2023;182:S70–1. https://doi.org/10.1016/S0167-8140(23)08524-9.

Article  Google Scholar 

Wada H, Nemoto K, Ogawa Y, Hareyama M, Yoshida H, Takamura A, Ohmori K, Hamamoto Y, Sugita T, Saitoh M, Yamada S. A multi-institutional retrospective analysis of external radiotherapy for mucosal melanoma of the head and neck in Northern Japan. Int J Radiat Oncol Biol Phys. 2004;59(2):495–500. https://doi.org/10.1016/j.ijrobp.2003.11.013.

Article  PubMed  Google Scholar 

Mizoe JE, Hasegawa A, Jingu K, Takagi R, Bessyo H, Morikawa T, Tonoki M, Tsuji H, Kamada T, Tsujii H, Okamoto Y, Organizing Committee for the Working Group for Head Neck Cancer. Results of carbon ion radiotherapy for head and neck cancer. Radiother Oncol. 2012;103(1):32–7. https://doi.org/10.1016/j.radonc.2011.12.013.

Article  Google Scholar 

Yanagi T, Mizoe JE, Hasegawa A, Takagi R, Bessho H, Onda T, Kamada T, Okamoto Y, Tsujii H. Mucosal malignant melanoma of the head and neck treated by carbon ion radiotherapy. Int J Radiat Oncol Biol Phys. 2009;74(1):15–20. https://doi.org/10.1016/j.ijrobp.2008.07.056.

Article  PubMed  Google Scholar 

Koto M, Demizu Y, Saitoh JI, Suefuji H, Tsuji H, Okimoto T, Ohno T, Shioyama Y, Takagi R, Nemoto K, Nakano T, Kamada T, Japan Carbon-Ion Radiation Oncology Study Group. Multicenter Study of Carbon-Ion Radiation Therapy for Mucosal Melanoma of the Head and Neck: Subanalysis of the Japan Carbon-Ion Radiation Oncology Study Group (J-CROS) Study (1402 HN). Int J Radiat Oncol Biol Phys. 2017;97(5):1054–60. https://doi.org/10.1016/j.ijrobp.2016.12.028.

Article  Google Scholar 

Ronchi S, Cicchetti A, Bonora M, Ingargiola R, Camarda AM, Russo S, Imparato S, Castelnuovo P, Pasquini E, Nicolai P, Ansarin M, Del Vecchio M, Benazzo M, Orlandi E, Vischioni B. Curative carbon ion radiotherapy in a head and neck mucosal melanoma series: Facing the future within multidisciplinarity. Radiother Oncol. 2023;11(190):110003. https://doi.org/10.1016/j.radonc.2023.110003.

Article  CAS  Google Scholar 

Hanaoka Y, Tanemura A, Takafuji M, Kiyohara E, Arase N, Suzuki O, Isohashi F, Ogawa K, Fujimoto M. Local and disease control for nasal melanoma treated with radiation and concomitant anti-programmed death 1 antibody. J Dermatol. 2020;47(4):423–5. https://doi.org/10.1111/1346-8138.15256.

Article  CAS  PubMed  Google Scholar 

Musha A, Kubo N, Kawamura H, Okano N, Sato H, Okada K, Tomizawa K, Ota N, Adachi A, Shino M, Nikkuni O, Ida S, Shirai K, Saitoh JI, Yokoo S, Chikamatsu K, Ohno T. Efficacy of immune checkpoint inhibitor treatment for head and neck mucosal melanoma recurrence in patients treated with carbon-ion radiotherapy. Cancer Rep (Hoboken). 2023;6(7):e1825. https://doi.org/10.1002/cnr2.1825.

Article  CAS  PubMed  Google Scholar 

Cavalieri S, Ronchi S, Barcellini A, Bonora M, Vischioni B, Vitolo V, Villa R, Del Vecchio M, Licitra L, Orlandi E. Toxicity of carbon ion radiotherapy and immune checkpoint inhibitors in advanced melanoma. Radiother Oncol. 2021;164:1–5. https://doi.org/10.1016/j.radonc.2021.08.021.

Article  CAS  PubMed  Google Scholar 

Llorente JL, López F, Suárez C, Hermsen MA. Sinonasal carcinoma: clinical, pathological, genetic and therapeutic advances. Nat Rev Clin Oncol. 2014;11(8):460–72. https://doi.org/10.1038/nrclinonc.2014.97.

Article  PubMed  Google Scholar 

Orlandi E, Cavalieri S, Granata R, Nicolai P, Castelnuovo P, Piazza C, Schreiber A, Turri-Zanoni M, Quattrone P, Miceli R, Infante G, Sessa F, Facco C, Calareso G, Iacovelli NA, Mattavelli D, Paderno A, Resteghini C, Locati LD, Licitra L, Bossi P. Locally advanced epithelial sinonasal tumors: The impact of multimodal approach. Laryngoscope. 2020;130(4):857–65. https://doi.org/10.1002/lary.28202.

Article  PubMed  Google Scholar 

Patel SH, Wang Z, Wong WW, Murad MH, Buckey CR, Mohammed K, Alahdab F, Altayar O, Nabhan M, Schild SE, Foote RL. Charged particle therapy versus photon therapy for paranasal sinus and nasal cavity malignant diseases: a systematic review and meta-analysis. Lancet Oncol. 2014;15(9):1027–38. https://doi.org/10.1016/S1470-2045(14)70268-2.

Article  CAS  PubMed  Google Scholar 

Ramaekers BL, Pijls-Johannesma M, Joore MA, van den Ende P, Langendijk JA, Lambin P, Kessels AG, Grutters JP. Systematic review and meta-analysis of radiotherapy in various head and neck cancers: comparing photons, carbon-ions and protons. Cancer Treat Rev. 2011;37(3):185–201. https://doi.org/10.1016/j.ctrv.2010.08.004.

Article  CAS  PubMed  Google Scholar 

Zhang W, Hu W, Hu J, Gao J, Yang J, Kong L, Lu JJ. Carbon ion radiation therapy for sinonasal malignancies: Promising results from 2282 cases from the real world. Cancer Sci. 2020;111:4465–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Resteghini C, Castelnuovo P, Nicolai P, Orlandi E, Bossi P, Vischioni B, Schreiber A, Gambazza S, Iacovelli NA, Battaglia P, Guzzo M, Turri-Zanoni M, Mattavelli D, Facchinetti N, Calareso G, Ravanelli M, Facco C, Tartaro T, Licitra L. The SINTART 1 study: A phase II non-randomised controlled trial of induction chemotherapy, surgery, photon-, proton- and carbon ion-based radiotherapy integration in patients with locally advanced resectable sinonasal tumours. Eur J Cancer. 2023;187:185–94. https://doi.org/10.1016/j.ejca.2023.03.033.

Article  CAS  PubMed  Google Scholar 

Bossi P, Orlandi E, Resteghini C, Vischioni B, Nicolai P, Castelnuovo P, Gambazza S, Locati LD, Turri-Zanoni M, Ferrari M, Facchinetti N, Iacovelli NA, Calareso G, Quattrone P, Cavallo A, Tuzi A, Licitra L. The SINTART 2 Study. A phase II non-randomised controlled trial of induction chemotherapy, photon-, proton- and carbon-ion-based radiotherapy integration in patients with locally advanced unresectable sinonasal tumours. Eur J Cancer. 2023;187:134–43. https://doi.org/10.1016/j.ejca.2023.03.034.

Article  CAS  PubMed  Google Scholar 

Mirandola A, Russo S, Bonora M, Vischioni B, Camarda AM, Ingargiola R, Molinelli S, Ronchi S, Rossi E, Vai A, Iacovelli NA, Thariat J, Ciocca M, Orlandi E. A Patient Selection Approach Based on NTCP Models and DVH Parameters for Definitive Proton Therapy in Locally Advanced Sinonasal Cancer Patients. Cancers (Basel). 2022;14(11):2678. https://doi.org/10.3390/cancers14112678.

Article  CAS  PubMed  Google Scholar 

Takiar V, Garden AS, Ma D, Morrison WH, Edson M, Zafereo ME, Gunn GB, Fuller CD, Beadle B, Frank SJ, William WN Jr, Kies M, El-Naggar AK, Weber R, Rosenthal DI, Phan J. Reirradiation of Head and Neck Cancers With Intensity Modulated Radiation Therapy: Outcomes and Analyses. Int J Radiat Oncol Biol Phys. 2016;95(4):1117–31. https://doi.org/10.1016/j.ijrobp.2016.03.015.

Article  PubMed 

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