peak drug concentration
HPLChigh-performance liquid chromatography
kaabsorption rate constant
LC-MS/MSliquid chromatography-tandem mass spectrometry
LLOQlower limit of quantitation
NCAnon-compartmental analysis
OFVobjective function value
Qintercompartmental clearance
QSPRquantitative structure–property relationship
RSErelative standard error
SAEMstochastic approximation expectation maximisation algorithm
tmaxtime to peak drug concentration
V1apparent volume of the central compartment
V2apparent volume of the peripheral compartment
KeywordsSubconjunctival pharmacokinetics
Dexamethasone
Ocular bioavailability
Intravenous pharmacokinetics
Population pharmacokinetic modelling
Non-compartmental analysis
Data availabilityData will be made available on request.
© 2024 The Authors. Published by Elsevier B.V.
留言 (0)