Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.
Soldevilla MM, Villanueva H, Pastor F. Aptamers: a feasible technology in cancer immunotherapy. J Immunol Res. 2016;2016:1083738.
Article CAS PubMed PubMed Central Google Scholar
Feng J, Li B, Ying J, Pan W, Liu C, Luo T, et al. Liquid biopsy: application in early diagnosis and monitoring of cancer. Small Struct. 2020;1(3):2000063.
Wang JJ, Lei KF, Han F. Tumor microenvironment: recent advances in various cancer treatments. Eur Rev Med Pharmacol Sci. 2018;22(12):3855–64.
He S, Du Y, Tao H, Duan H. Advances in aptamer-mediated targeted delivery system for cancer treatment. Int J Biol Macromol. 2023;238: 124173.
Article CAS PubMed Google Scholar
Wu H-C, Chang D-K, Huang C-T. Targeted therapy for cancer. J Cancer Mol. 2006;2(2):57–66.
Bashash D, Zandi Z, Kashani B, Pourbagheri-Sigaroodi A, Salari S, Ghaffari SH. Resistance to immunotherapy in human malignancies: mechanisms, research progresses, challenges, and opportunities. J Cell Physiol. 2022;237(1):346–72.
Article CAS PubMed Google Scholar
Ellis LM, Hicklin DJ. Resistance to targeted therapies: refining anticancer therapy in the era of molecular oncology. Clin Cancer Res. 2009;15(24):7471–8.
Article CAS PubMed Google Scholar
Yadav P, Ambudkar SV, Rajendra PN. Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer. J Nanobiotechnol. 2022;20(1):1–35.
Lorscheider M, Gaudin A, Nakhle J, Veiman KL, Richard J, Chassaing C. Challenges and opportunities in the delivery of cancer therapeutics: update on recent progress. Ther Deliv. 2021;12(1):55–76.
Article CAS PubMed Google Scholar
Hegde PS, Chen DS. Top 10 challenges in cancer immunotherapy. Immunity. 2020;52(1):17–35.
Article CAS PubMed Google Scholar
Han J, Gao L, Wang J, Wang J. Application and development of aptamer in cancer: from clinical diagnosis to cancer therapy. J Cancer. 2020;11(23):6902–15.
Article CAS PubMed PubMed Central Google Scholar
Eriksson ESE, Joshi L, Billeter M, Eriksson LA. De novo tertiary structure prediction using RNA123—benchmarking and application to Macugen. J Mol Model. 2014;20(8):2389.
Mehta J, Van Dorst B, Rouah-Martin E, Herrebout W, Scippo M-L, Blust R, et al. In vitro selection and characterization of DNA aptamers recognizing chloramphenicol. J Biotechnol. 2011;155(4):361–9.
Article CAS PubMed Google Scholar
Kong HY, Byun J. Nucleic acid aptamers: new methods for selection, stabilization, and application in biomedical science. Biomol Ther. 2013;21(6):423.
Hayashi T, Oshima H, Mashima T, Nagata T, Katahira M, Kinoshita M. Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition. Nucleic Acids Res. 2014;42(11):6861–75.
Article CAS PubMed PubMed Central Google Scholar
Yang LF, Ling M, Kacherovsky N, Pun SH. Aptamers 101: aptamer discovery and in vitro applications in biosensors and separations. Chem Sci. 2023;14(19):4961–78.
Article CAS PubMed PubMed Central Google Scholar
Zhou J, Rossi J. Aptamers as targeted therapeutics: current potential and challenges. Nat Rev Drug Discov. 2017;16(3):181–202.
Article CAS PubMed Google Scholar
Reverdatto S, Burz DS, Shekhtman A. Peptide aptamers: development and applications. Curr Top Med Chem. 2015;15(12):1082.
Article CAS PubMed PubMed Central Google Scholar
Thiviyanathan V, Gorenstein DG. Aptamers and the next generation of diagnostic reagents. Proteomics Clin Appl. 2012;6(11–12):563–73.
Article CAS PubMed PubMed Central Google Scholar
Nimjee SM, Rusconi CP, Sullenger BA. Aptamers: an emerging class of therapeutics. Annu Rev Med. 2005;56:555–83.
Article CAS PubMed Google Scholar
Constantinou A, Chen C, Deonarain M. Modulating the pharmacokinetics of therapeutic antibodies. Biotech Lett. 2010;32:609–22.
Sharifi J, Khawli L, Hornick J, Epstein A. Improving monoclonal antibody pharmacokinetics via chemical modification. Q J Nucl Med Mol Imaging. 1998;42(4):242.
Stoltenburg R, Reinemann C, Strehlitz B. SELEX—A (r) evolutionary method to generate high-affinity nucleic acid ligands. Biomol Eng. 2007;24(4):381–403.
Article CAS PubMed Google Scholar
Liu Q, Zhang W, Chen S, Zhuang Z, Zhang Y, Jiang L, et al. SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding. J Biol Eng. 2020;14:1–13.
Article CAS PubMed PubMed Central Google Scholar
Zhuo Z, Yu Y, Wang M, Li J, Zhang Z, Liu J, et al. Recent advances in SELEX technology and aptamer applications in biomedicine. Int J Mol Sci. 2017;18(10):2142.
Article PubMed PubMed Central Google Scholar
Buglak AA, Samokhvalov AV, Zherdev AV, Dzantiev BB. Methods and applications of in silico aptamer design and modeling. Int J Mol Sci. 2020;21(22):8420.
Article CAS PubMed PubMed Central Google Scholar
Zhu G, Chen X. Aptamer-based targeted therapy. Adv Drug Deliv Rev. 2018;134:65–78.
Article CAS PubMed PubMed Central Google Scholar
Li W, Bing T, Wang R, Jin S, Shangguan D, Chen H. Cell-SELEX-based selection of ssDNA aptamers for specifically targeting BRAF V600E-mutated melanoma. Analyst. 2022;147(1):187–95.
Article ADS CAS Google Scholar
Sun D, Sun M, Zhang J, Lin X, Zhang Y, Lin F, et al. Computational tools for aptamer identification and optimization. TrAC, Trends Anal Chem. 2022;157: 116767.
Zhang N, Chen Z, Liu D, Jiang H, Zhang Z-K, Lu A, et al. Structural biology for the molecular insight between aptamers and target proteins. Int J Mol Sci. 2021;22(8):4093.
Article CAS PubMed PubMed Central Google Scholar
Musafia B, Oren-Banaroya R, Noiman S. Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interaction. PLoS ONE. 2014;9(5): e97696.
Article ADS PubMed PubMed Central Google Scholar
Li X, Chung LW, Li G. Multiscale simulations on spectral tuning and the photoisomerization mechanism in fluorescent RNA spinach. J Chem Theory Comput. 2016;12(11):5453–64.
Article CAS PubMed Google Scholar
Hoinka J, Przytycka T. AptaPLEX – a dedicated, multithreaded demultiplexer for HT-SELEX data. Methods. 2016;106:82–5.
Article CAS PubMed Google Scholar
Hoinka J, Zotenko E, Friedman A, Sauna ZE, Przytycka TM. Identification of sequence–structure RNA binding motifs for SELEX-derived aptamers. Bioinformatics. 2012;28(12):i215–23.
Article PubMed PubMed Central Google Scholar
Thiel WH, Giangrande PH. Analyzing HT-SELEX data with the Galaxy Project tools – a web based bioinformatics platform for biomedical research. Methods. 2016;97:3–10.
Article CAS PubMed Google Scholar
Thiel WH. Galaxy workflows for web-based bioinformatics analysis of aptamer high-throughput sequencing data. Mol Ther Nucleic Acids. 2016;5: e345.
Article ADS CAS PubMed PubMed Central Google Scholar
Shieh KR, Kratschmer C, Maier KE, Greally JM, Levy M, Golden A. AptCompare: optimized de novo motif discovery of RNA aptamers via HTS-SELEX. Bioinformatics. 2020;36(9):2905–6.
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