Physiological and immunological barriers in the lung

Davis JD, Wypych TP (2021) Cellular and functional heterogeneity of the airway epithelium. Mucosal Immunol 14(5):978–990

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hallstrand TS, Hackett TL, Altemeier WA, Matute-Bello G, Hansbro PM, Knight DA (2014) Airway epithelial regulation of pulmonary immune homeostasis and inflammation. Clin Immunol 151(1):1–15

Article  CAS  PubMed  Google Scholar 

Saku A, Hirose K, Ito T, Iwata A, Sato T et al (2019) Fucosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite-induced airway inflammation. J Allergy Clin Immunol 144(3):698-709.e9

Article  CAS  PubMed  Google Scholar 

Nishimura N, Yokota M, Kurihara S, Iwata A, Kageyama T et al (2022) Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1. Allergol Int 71(4):520–527

Article  CAS  PubMed  Google Scholar 

Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M et al (2018) Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature 560(7720):649–654

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ravanetti L, Dijkhuis A, Dekker T, Sabogal Pineros YS, Ravi A et al (2019) IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity. J Allergy Clin Immunol 143(4):1355-1370.e16

Article  CAS  PubMed  Google Scholar 

Veerati PC, Troy NM, Reid AT, Li NF, Nichol KS et al (2020) Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD. Front Immunol 11:974

Article  CAS  PubMed  PubMed Central  Google Scholar 

Doni Jayavelu N, Altman MC, Benson B, Dufort MJ, Vanderwall ER et al (2023) Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells. J Allergy Clin Immunol 152(1):56–67

Article  CAS  PubMed  Google Scholar 

Corren J, Parnes JR, Wang L, Mo M, Roseti SL et al (2017) Tezepelumab in adults with uncontrolled asthma. N Engl J Med 377(10):936–946

Article  CAS  PubMed  Google Scholar 

Yin Z, Zhou Y, Turnquist HR, Liu Q (2022) Neuro-epithelial-ILC2 crosstalk in barrier tissues. Trends Immunol 43(11):901–916

Article  CAS  PubMed  Google Scholar 

Talbot S, Abdulnour R-EE, Burkett PR, Lee S, Cronin SJF et al (2015) Silencing nociceptor neurons reduces allergic airway inflammation. Neuron 87(2):341–354

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour R-EE, Nyman J et al (2017) The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature 549(7672):351–356

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu W, Wang S, Wang J, Zheng R, Wang D et al (2023) Neuromedin U induces pulmonary ILC2 activation via the NMUR1 pathway during acute respiratory syncytial virus infection. Am J Respir Cell Mol Biol 68(3):256–266

Article  CAS  PubMed  Google Scholar 

Sui P, Wiesner DL, Xu J, Zhang Y, Lee J et al (2018) Pulmonary neuroendocrine cells amplify allergic asthma responses. Science 360:eaan8546

Hewitt RJ, Lloyd CM (2021) Regulation of immune responses by the airway epithelial cell landscape. Nat Rev Immunol 21(6):347–362

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guillot L, Nathan N, Tabary O, Thouvenin G, Le Rouzic P et al (2013) Alveolar epithelial cells: master regulators of lung homeostasis. Int J Biochem Cell Biol 45(11):2568–2573

Article  CAS  PubMed  Google Scholar 

Hellings PW, Steelant B (2020) Epithelial barriers in allergy and asthma. J Allergy Clin Immunol 145(6):1499–1509

Article  PubMed  PubMed Central  Google Scholar 

Wittekindt OH (2017) Tight junctions in pulmonary epithelia during lung inflammation. Pflugers Arch 469(1):135–147

Article  CAS  PubMed  Google Scholar 

Koval M (2013) Claudin heterogeneity and control of lung tight junctions. Annu Rev Physiol 75:551–567

Article  CAS  PubMed  Google Scholar 

Georas SN, Rezaee F (2014) Epithelial barrier function: at the front line of asthma immunology and allergic airway inflammation. J Allergy Clin Immunol 134(3):509–520

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiao C, Puddicombe SM, Field S, Haywood J, Broughton-Head V et al (2011) Defective epithelial barrier function in asthma. J Allergy Clin Immunol 128(3):549–556.e1-12

de Boer WI, Sharma HS, Baelemans SMI, Hoogsteden HC, Lambrecht BN, Braunstahl GJ (2008) Altered expression of epithelial junctional proteins in atopic asthma: possible role in inflammation. Can J Physiol Pharmacol 86(3):105–112

Article  PubMed  Google Scholar 

Nishida K, Brune KA, Putcha N, Mandke P, O’Neal WK, et al. (2017) Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Am J Physiol Lung Cell Mol. Physiol. 313(3):L581–91

Rusznak C, Mills PR, Devalia JL, Sapsford RJ, Davies RJ, Lozewicz S (2000) Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 23(4):530–536

Article  CAS  PubMed  Google Scholar 

Thornton DJ, Rousseau K, McGuckin MA (2008) Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol 70:459–486

Article  CAS  PubMed  Google Scholar 

Radicioni G, Ceppe A, Ford AA, Alexis NE, Barr RG et al (2021) Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med 9(11):1241–1254

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henderson AG, Ehre C, Button B, Abdullah LH, Cai L-H et al (2014) Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest 124(7):3047–3060

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henke MO, John G, Germann M, Lindemann H, Rubin BK (2007) MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation. Am J Respir Crit Care Med 175(8):816–821

Article  CAS  PubMed  Google Scholar 

Lachowicz-Scroggins ME, Yuan S, Kerr SC, Dunican EM, Yu M et al (2016) Abnormalities in MUC5AC and MUC5B protein in airway mucus in asthma. Am J Respir Crit Care Med 194(10):1296–1299

Article  CAS  PubMed  PubMed Central  Google Scholar 

Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE et al (2014) Muc5b is required for airway defence. Nature 505(7483):412–416

Article  CAS  PubMed  Google Scholar 

Hill DB, Button B, Rubinstein M, Boucher RC (2022) Physiology and pathophysiology of human airway mucus. Physiol Rev 102(4):1757–1836

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singh G, Acharya S, Shukla S, Jain D (2023) Muco-obstructive lung disease: a systematic review. Cureus 15(10):e46866

PubMed  PubMed Central  Google Scholar 

Renegar KB, Small PA Jr, Boykins LG, Wright PF (2004) Role of IgA versus IgG in the control of influenza viral infection in the murine respiratory tract. J Immunol 173(3):1978–1986

Article  CAS  PubMed  Google Scholar 

Oh JE, Song E, Moriyama M, Wong P, Zhang S et al (2021) Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA. Sci Immunol 6(66):eabj5129

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bohländer F (2023) A new hope? Possibilities of therapeutic IgA antibodies in the treatment of inflammatory lung diseases. Front Immunol 14:1127339

Article  PubMed  PubMed Central  Google Scholar 

Blackburn JB, Schaff JA, Gutor S, Du R-H, Nichols D et al (2022) Secretory cells are the primary source of pIgR in small airways. Am J Respir Cell Mol Biol 67(3):334–345

Article  CAS  PubMed  PubMed Central  Google Scholar 

Diebel LN, Amin PB, Liberati DM (2010) Sequence of immunoglobulin isotype exposure modulates inflammatory response to bacteria and lipopolysaccharide in vitro. Surg Infect 11(2):145–150

Article  Google Scholar 

Ladjemi MZ, Martin C, Lecocq M, Detry B, Nana FA et al (2019) Increased IgA expression in lung lymphoid follicles in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 199(5):592–602

Article

留言 (0)

沒有登入
gif