Rubenstein JH, Shaheen NJ. Epidemiology, diagnosis, and management of esophageal adenocarcinoma. Gastroenterology. 2015;149(2):302-317.e1.
Frederik HJ, Lars P, Mohr DA, Toft SH, Peter FJ. Incidence of adenocarcinoma among patients with Barrett’s esophagus. N Engl J Med. 2011;365(15):1375–83.
Wu AH, Tseng CC, Bernstein L. Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma. Cancer. 2003;98(5):940–8.
Lagergren J, Bergström R, Lindgren A, Nyrén O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med. 1999;340(11):825–31.
Turati F, Tramacere I, La Vecchia C, Negri E. A meta-analysis of body mass index and esophageal and gastric cardia adenocarcinoma. Ann Oncol. 2013;24(3):609–17.
Eyck BM, van Lanschot JJB, Hulshof MCCM, van der Wilk BJ, Shapiro J, van Hagen P, et al. Ten-Year outcome of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer: the randomized controlled CROSS trial. J Clin Oncol. 2021;39(18):1995–2004.
Cunningham D. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med. 2006;355(1):11–20.
Ychou M, Boige V, Pignon JP, Conroy T, Bouché O, Lebreton G, et al. Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III trial. JCO. 2011;29(13):1715–21.
Shapiro J, van Lanschot JJB, Hulshof MCCM, van Hagen P, van Berge Henegouwen MI, Wijnhoven BPL, et al. Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial. Lancet Oncol. 2015;16(9):1090–8.
van Hagen P, Hulshof MCCM, van Lanschot JJB, Steyerberg EW, van Berge Henegouwen MI, Wijnhoven BPL, et al. Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med. 2012;366(22):2074–84.
Al-Batran SE, Homann N, Pauligk C, Goetze TO, Meiler J, Kasper S, et al. Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. The Lancet. 2019;393(10184):1948–57.
Kelly RJ, Ajani JA, Kuzdzal J, Zander T, Van Cutsem E, Piessen G, et al. Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer. N Engl J Med. 2021;384(13):1191–203.
Stroes CI, Schokker S, Creemers A, Molenaar RJ, Hulshof MCCM, van der Woude SO, et al. Phase II feasibility and biomarker study of neoadjuvant trastuzumab and pertuzumab with chemoradiotherapy for resectable human epidermal growth factor receptor 2–positive esophageal adenocarcinoma: TRAP study. JCO. 2020;38(5):462–71.
Hulshof MCCM, Geijsen ED, Rozema T, Oppedijk V, Buijsen J, Neelis KJ, et al. Randomized study on dose escalation in definitive chemoradiation for patients with locally advanced esophageal cancer (ARTDECO Study). JCO. 2021;39(25):2816–24.
Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson JA Jr, Al-Sarraf M, et al. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85–01). JAMA. 1999;281(17):1623–7.
Conroy T, Galais MP, Raoul JL, Bouché O, Gourgou-Bourgade S, Douillard JY, et al. Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial. Lancet Oncol. 2014;15(3):305–14.
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA A Cancer J Clin. 2020;70(1):7–30.
Motoyama S, Maeda E, Iijima K, Anbai A, Sato Y, Wakita A, et al. Differences in treatment and survival between elderly patients with thoracic esophageal cancer in metropolitan areas and other areas. Cancer Sci. 2021;112(10):4281–91.
Article PubMed PubMed Central Google Scholar
Won E, Ilson DH. Management of localized esophageal cancer in the older patient. Oncologist. 2014;19(4):367–74.
Article PubMed PubMed Central Google Scholar
Mantziari S, Teixeira Farinha H, Bouygues V, Vignal JC, Deswysen Y, Demartines N, et al. Esophageal cancer in elderly patients, current treatment options and outcomes; a systematic review and pooled analysis. Cancers. 2021;13(9):2104.
Article PubMed PubMed Central Google Scholar
Xia X, Gao Q, Ge X, Liu Z, Di X, Sun X, et al. Chemoradiotherapy is superior to radiotherapy alone in esophageal cancer patients older than 65 years: a propensity score-matched analysis of the SEER database. Front Oncol. 2021;7(11): 736448.
Jingu K, Numasaki H, Toh Y, Nemoto K, Uno T, Doki Y, et al. Chemoradiotherapy and radiotherapy alone in patients with esophageal cancer aged 80 years or older based on the comprehensive registry of esophageal cancer in Japan. Esophagus. 2020;17(3):223–9.
Yang Y, Chen M, Xie J, Ji Y, Sheng L, Qiu G, et al. Treatment patterns and outcomes of elderly patients with potentially curable esophageal cancer. Front Oncol. 2022;14(12): 778898.
Suzuki G, Yamazaki H, Aibe N, Masui K, Kimoto T, Shimizu D, et al. Definitive radiotherapy for older patients aged ≥75 years with localized esophageal cancer. In Vivo. 2019;33(3):925–32.
Article PubMed PubMed Central Google Scholar
Herskovic A, Martz K, Al-Sarraf M, Leichman L, Brindle J, Vaitkevicius V, et al. Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med. 1992;326(24):1593–8.
Bostel T, Akbaba S, Wollschläger D, Mayer A, Nikolaidou E, Murnik M, et al. Chemoradiotherapy in geriatric patients with squamous cell carcinoma of the esophagus: multi-center analysis on the value of standard treatment in the elderly. Front Oncol. 2023;3(13):1063670.
Bedenne L, Michel P, Bouché O, Milan C, Mariette C, Conroy T, et al. Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102. JCO. 2007;25(10):1160–8.
Stahl M, Stuschke M, Lehmann N, Meyer HJ, Walz MK, Seeber S, et al. Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus. JCO. 2005;23(10):2310–7.
Minsky BD, Pajak TF, Ginsberg RJ, Pisansky TM, Martenson J, Komaki R, et al. INT 0123 (Radiation therapy oncology group 94–05) phase III trial of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy. J Clin Oncol. 2002;20(5):1167–74.
Mayer A, Wenzel W, Wollschläger D, Bostel T, Krüger M, Matthias C, et al. Adjuvant chemoradiotherapy in elderly patients with head and neck cancer: a monoinstitutional, two-to-one pair-matching analysis. Strahlenther Onkol. 2022;198(2):159–70.
Article PubMed PubMed Central Google Scholar
Haehl E, Rühle A, David H, Kalckreuth T, Sprave T, Stoian R, et al. Radiotherapy for geriatric head-and-neck cancer patients: what is the value of standard treatment in the elderly? Radiat Oncol. 2020;15(1):31.
Article PubMed PubMed Central Google Scholar
Ji Y, Du X, Zhu W, Yang Y, Ma J, Zhang L, et al. Efficacy of concurrent chemoradiotherapy with S-1 vs radiotherapy alone for older patients with esophageal cancer: a multicenter randomized phase 3 clinical trial. JAMA Oncol. 2021;7(10):1459–66.
Lv H, Chao C, Wang B, Wang Z, Qian Y, Zhang X. The effect of surgery plus chemoradiotherapy on survival of elderly patients with stage II-III esophageal cancer: a SEER-based demographic analysis. Cancer Med. 2021;10(23):8483–96.
Article PubMed PubMed Central Google Scholar
Jingu K, Takahashi N, Umezawa R, Yamamoto T, Takeda K, Suzuki Y, et al. The benefit of concurrent chemotherapy with radiotherapy for esophageal cancer is limited in Asian patients aged 80 years or older: a SEER database analysis. Esophagus. 2022;19(4):653–9.
Cooper L, Dezube AR, De León LE, Kucukak S, Mazzola E, Dumontier C, et al. Outcomes of trimodality CROSS regimen in older adults with locally advanced esophageal cancer. Eur J Surg Oncol. 2021;47(10):2667–74.
Article PubMed PubMed Central Google Scholar
Gaber CE, Shaheen NJ, Edwards JK, Sandler RS, Nichols HB, Sanoff HK, et al. Trimodality therapy vs definitive chemoradiation in older adults with locally advanced esophageal cancer. JNCI Cancer Spectrum. 2022;6(6):pkac069.
Article PubMed PubMed Central Google Scholar
Chow R, Chiu N, Bruera E, Krishnan M, Chiu L, Lam H, et al. Inter-rater reliability in performance status assessment among health care professionals: a systematic review. Ann Palliat Med. 2016;5(2):832–92.
Disalvo D, Moth E, Soo WK, Garcia MV, Blinman P, Steer C, et al. The effect of comprehensive geriatric assessment on care received, treatment completion, toxicity, cancer-related and geriatric assessment outcomes, and quality of life for older adults receiving systemic anti-cancer treatment: a systematic review. J Geriatr Oncol. 2023;10: 101585.
Magnuson A, Sedrak MS, Gross CP, Tew WP, Klepin HD, Wildes TM, et al. Development and validation of a risk tool for predicting severe toxicity in older adults receiving chemotherapy for early-stage breast cancer. J Clin Oncol. 2021;39(6):608–18.
Article PubMed PubMed Central Google Scholar
Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, et al. Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology. J Clin Oncol. 2018;36(22):2326–47.
留言 (0)