Alanen P, Isokangas P, Gutmann K. Xylitol candies in caries prevention: results of a field study in Estonian children. Community Dent Oral Epidemiol. 2000;28:218–24. https://doi.org/10.1034/j.1600-0528.2000.280308.x.
Article CAS PubMed Google Scholar
ALHumaid J, Bamashmous M. Meta-analysis on the effectiveness of xylitol in caries prevention. J Int Soc Prevent Communit Dent. 2022;12:133–8. https://doi.org/10.4103/jispcd.jispcd_164_21
Antonio AG, Pierro VS, Maia LC. Caries preventive effects of xylitol-based candies and lozenges: a systematic review. J Public Health Dent. 2011;71:117–24. https://doi.org/10.1111/j.1752-7325.2010.00208.x.
Campus G, Cagetti MG, Sacco G, Solinas G, Mastroberardino S, Lingström P. Six months of daily high-dose xylitol in high-risk schoolchildren: a randomized clinical trial on plaque pH and salivary mutans streptococci. Caries Res. 2009;43:455–61. https://doi.org/10.1159/000264682.
Article CAS PubMed Google Scholar
Campus G, Cagetti MG, Sale S, Petruzzi M, Solinas G, Strohmenger L, Lingström P. Six months of high-dose xylitol in high-risk caries subjects—a 2-year randomised, clinical trial. Clin Oral Invest. 2013;17:785–91. https://doi.org/10.1007/s00784-012-0774-5.
Deshpande A, Jadad AR. The impact of polyol-containing chewing gums on dental caries: a systematic review of original randomized controlled trials and observational studies. J Am Dent Assoc. 2008;139:1602–14. https://doi.org/10.14219/jada.archive.2008.0102
Havenaar R, Huis in’t Veld JHJ, Backer Dirks O, de Stoppelaar JD. Some bacteriological aspects of sugar substitutes. In: Guggenheim, B, editor. Health and Sugar Substitutes: Proceedings of the Ergob Conference on Sugar Substitutes, Geneva, 1978. Basel: Karger; 1978. pp. 192–8. https://ocul-gue.primo.exlibrisgroup.com/discovery/fulldisplay/alma9922118913505154/01OCUL_GUE:GUELPH
He S, Choong EKM, Duangthip D, Chu CH, Lo ECM. Clinical interventions with various agents to prevent early childhood caries: A systematic review with network meta-analysis. Int J Paediatr Dent. 2023. https://doi.org/10.1111/ipd.13055.
Hietala-Lenkkeri A. Evaluation of xylitol use and bitewing radiographs among school-aged children in a low-caries level population. Thesis, Annales Universitatis Turkuensis D 1254. Turku: University of Turku; 2016. https://www.utupub.fi
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane 2022.
Honkala E, Honkala S, Shyama M, Al-Mutawa SA. Field trial on caries prevention with candies among disabled school students. Caries Res. 2006;40:508–13.
Article CAS PubMed Google Scholar
Honkala S, Runnel R, Saag M, Olak J, Nommela R, Russak S, Mäkinen PL, Vahlberg T, Falony F, Mäkinen K, Honkala E. Effect of erythritol and xylitol on dental caries prevention in children. Caries Res. 2014;48:482–90.
Article CAS PubMed Google Scholar
Isokangas P. Xylitol chewing gum in caries prevention. A longitudinal study on Finnish school children. Proc Finn Dent Soc. 1987;83: Suppl. I
Isokangas P, Alanen P, Tiekso J, Mäkinen KK. Xylitol chewing gum in caries prevention: a field study in children. J Am Dent Assoc. 1988;117:315–20.
Article CAS PubMed Google Scholar
Janakiram C, Deepan Kumar CV, Joseph J. Xylitol in preventing dental caries. A systematic review and meta-analyses. J Nat Sc Biol Med. 2017;8:16–21.
Kandelman D, Gagnon G. Clinical results after 12 months from a study of the incidence and progression of dental caries in relation to consumption of chewing-gum containing xylitol in school preventive programs. J Dent Res. 1987;66:1407–11.
Article CAS PubMed Google Scholar
Kandelman D, Bär A, Hefti A.Collaborative WHO xylitol field study in French Polynesia. I. Baseline prevalence and 32-month caries increment. Caries Res 1988;22:55–62.
Kandelman D, Gagnon G. A 24-month clinical study of the incidence and progression of dental caries in relation to consumption of chewing gum containing xylitol in school preventive programs. J Dent Res. 1990;69:1771–5.
Article CAS PubMed Google Scholar
Kovari H. The use of xylitol gum at day-care centers. Experimental follow-up study. Thesis, Annales Universitatis Turkuensis C 186. Turku: University of Turku; 2002. https://www.utupub.fi
Kovari H, Pienihäkkinen K, Alanen P. Use of xylitol chewing gum in daycare centers: a follow-up study in Savonlinna, Finland. Acta Odontol Scand. 2003;61:367–70.
Article CAS PubMed Google Scholar
Laitala ML, Alanen P, Isokangas P, Söderling E, Pienihäkkinen K. Long-term effects of maternal prevention on children’s dental decay and need for restorative treatment. Community Dent Oral Epidemiol. 2013;41:534–40.
Lee W, Spiekerman C, Heima M, Eggertsson H, Ferretti G, Milgrom P, Nelson S. The effectiveness of xylitol in a school-based cluster-randomized clinical trial. Caries Res. 2015;49:41–9.
Article CAS PubMed Google Scholar
Lenkkeri AMH, Pienihäkkinen K, Hurme S, Alanen P. The caries-preventive effect of xylitol/maltitol and erythritol/maltitol lozenges: results of a double-blinded, cluster-randomized clinical trial in an area of natural fluoridation. Int J Paediatr Dent. 2012;22:180–90. https://doi.org/10.1111/j.1365-263X.2011.01182.x.
Li Y, Tanner A. Effect of antimicrobial intervention on oral microbiota associated with early childhood caries. Pediatr Dent. 2015;37:226–44.
PubMed PubMed Central Google Scholar
Lif Holgerson P, Stecksén-Blicks C, Sjöström I. Xylitol concentration in saliva and dental plaque after use of various xylitol-containing products. Caries Res. 2006;40:393–7.
Article CAS PubMed Google Scholar
Lingström P, Holm AK, Mejáre I, Twetman S, Söder B, Norlund A, Axelsson S, Lagerlöf F, Nordenram G, Petersson LG, Dahlgren H, Källestål C. Dietary factors in the prevention of dental caries: a systematic review. Acta Odontol Scand. 2003;61:331–40.
Ly KA, Milgrom P, Roberst MC, Yamaguchi DK, Rothen M, Mueller G. Linear response of mutans streptococci to increasing xylitol gum use: a randomized controlled trial. BMC Oral Health. 2006. https://doi.org/10.1186/1472-6831-6-6.
Article PubMed PubMed Central Google Scholar
Machiulskiene V, Nyvad B, Baelum V. Caries preventive effect of sugar-substituted chewing gum. Community Dent Oral Epidemiol. 2001;29:278–88.
Article CAS PubMed Google Scholar
Marghalani AA, Guinto E, Phan M, Dhar V, Tinanoff N. Effectiveness of xylitol in reducing dental caries in children. Pediatr Dent. 2017;39:103–10.
Massler M, Pindborg JJ, Mohammed C. A compilation of epidemiologic studies in dental caries. Dental Caries. 1954;44:1357–62.
Mickenautsch S, Leal SC, Yengopal V, Bezerra AC, Cruvinel V. Sugar-free chewing gum and dental caries: a systematic review. J Appl Oral Sci. 2007;15:83–8.
Article CAS PubMed PubMed Central Google Scholar
Milgrom P, Ly KA, Roberts MC, Rothen M, Mueller G, Yamaguchi DK. Mutans streptococci dose response to xylitol chewing gum. J Dent Res. 2006;85:177–81.
Article CAS PubMed Google Scholar
Milgrom P, Ly KA, Tut OK, Mancl L, Roberts MC, Briand K, Gancio MJ. Xylitol pediatric topical oral syrup to prevent dental caries: a double-blind randomized clinical trial of efficacy. Arch Pediatr Adolesc Med. 2009;163:601–7.
Article PubMed PubMed Central Google Scholar
Mäkinen KK, Bennett CA, Hujoel PP, Isokangas PJ, Isotupa KP, Pape HR Jr, Mäkinen PL. Xylitol chewing gums and caries rates: a 40-month cohort study. J Dent Res. 1995;74:1904–13.
Mäkinen KK, Hujoel PP, Bennett CA, Isotupa KP, Mäkinen PL, Allen P. Polyol chewing gums and caries rates in primary dentition: a 24-month cohort study. Caries Res. 1996;30:408–17.
Mäkinen KK. Gastrointestinal disturbances associated with the consumption of sugar alcohols with special consideration of xylitol: scientific review and instructions for dentists and other health-care professionals. Int J Dent. 2016;2016:5967907.
Article PubMed PubMed Central Google Scholar
Mota KR, da Silva JVF, Borges CD, Leite de Marcelos PGC, Alvares PR, Santos Júnior VED. Effectiveness of the use of xylitol chewing gum in prevention of dental caries: A systematic review. J Indian Soc Pedod Prev Dent. 2021;39(2):113–119. https://doi.org/10.4103/JISPPD.JISPPD_330_20. PMID: 34341229.
Nasseripour M, Newton JT, Warburton F, Awojobi O, Di Giorgio S, Gallagher JE, Banerjee A. A systematic review and meta-analysis of the role of sugar-free chewing gum on plaque quantity in the oral cavity. Front Oral Health. 2022;3: 845921. https://doi.org/10.3389/froh.2022.845921.
Article PubMed PubMed Central Google Scholar
Newton JT, Awojobi O, Nasseripour M, Warburton F, Di Giorgio S, Gallagher JE, Banerjee A. A systematic review and meta-analysis of the role of sugar-free chewing gum in dental caries. JDR Clin Trans Res. 2020;5:214–23.
Nørrisgaard PE, Qvist V, Ekstrand K. Prevalence, risk surfaces and inter-municipality variations in caries experience in Danish children and adolescents in 2012. Acta Odontol Scand. 2016;74:291–7. https://doi.org/10.3109/00016357.2015.1119306.
Oscarson P, Lif Holgerson P, Sjöström I, Twetman S, Stecksén-Blicks C. Influence of a low xylitol-dose on mutans streptococci colonization and caries development in preschool children. Eur Arch Paediatr Dent. 2006;7:142–7.
Article CAS PubMed Google Scholar
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71. https://doi.org/10.1136/bmj.n71.
Article PubMed PubMed Central Google Scholar
Petersen PE. The World Oral Health Report 2003: continuous improvement of oral health in the 21st century – the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol. 2003;31(Suppl. 1):3–24.
Rethman MP, Beltrán-Aquilar ED, Billings RJ, Hujoel PP, Katz BP, Milgrom P, Sohn W, Stamm JW, Watson G, Wolff M, Wright JT, Zero D, Aravamudhan K, Frantsve-Hawley J, Meyer DM. American Dental Association Council on Scientific Affairs Expert Panel on Nonfluoride Caries-Preventive Agents. Nonfluoride caries-preventive agents: executive summary of evidence-based clinical recommendations. J Am Dent Assoc. 2011;142:1065–71.
Riley P, Moore D, Ahmed F, Sharif MO, Worthington HV. Xylitol-containing products for preventing dental caries in children and adults. Cochrane Database of Syst Rev. 2015;26(3):CD010743.
Ruiken R, König K, Truin GJ, Plasschaert F. Longitudinal study of dental caries development in Dutch children aged 8–12 years. Comm Dent Oral Epidemiol. 1986;14:53–6.
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