Ahmad FB, Cisewski JA, Minino A, Anderson RN. Provisional mortality data - United States, 2020. MMWR Morb Mortal Wkly Rep. 2021;70(14):519–22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Centers for Disease Control and Prevention. Drug Overdose Deaths. https://www.cdc.gov/drugoverdose/deaths/index.html. (Accessed: 10/30/23). 2023.

Spencer MR MA, Warner M. . Drug overdose deaths in the United States, 2001–2021. NCHS Data Brief, no 457. Hyattsville, MD: National Center for Health Statistics https://www.cdcgov/nchs/products/databriefs/db457htm. 2022.

Sporer KA, Kral AH. Prescription naloxone: a novel approach to heroin overdose prevention. Ann Emerg Med. 2007;49(2):172–7.

Article  PubMed  Google Scholar 

Coffin PO, Fuller C, Vadnai L, Blaney S, Galea S, Vlahov D. Preliminary evidence of health care provider support for naloxone prescription as overdose fatality prevention strategy in New York City. J Urban Health. 2003;80(2):288–90.

Article  PubMed  PubMed Central  Google Scholar 

Seal KH, Thawley R, Gee L, Bamberger J, Kral AH, Ciccarone D, et al. Naloxone distribution and cardiopulmonary resuscitation training for injection drug users to prevent heroin overdose death: a pilot intervention study. J Urban Health. 2005;82(2):303–11.

Article  PubMed  PubMed Central  Google Scholar 

Belz D, Lieb J, Rea T, Eisenberg MS. Naloxone use in a tiered-response emergency medical services system. Prehosp Emerg Care. 2006;10(4):468–71.

Article  PubMed  Google Scholar 

Buajordet I, Naess AC, Jacobsen D, Brors O. Adverse events after naloxone treatment of episodes of suspected acute opioid overdose. Eur J Emerg Med. 2004;11(1):19–23.

Article  PubMed  Google Scholar 

Ashton H, Hassan Z. Best evidence topic report. Intranasal naloxone in suspected opioid overdose. Emerg Med J. 2006;23(3):221–3.

Article  PubMed  Google Scholar 

Baca CT, Grant KJ. Take-home naloxone to reduce heroin death. Addiction. 2005;100(12):1823–31.

Article  PubMed  Google Scholar 

Barton ED, Colwell CB, Wolfe T, Fosnocht D, Gravitz C, Bryan T, et al. Efficacy of intranasal naloxone as a needleless alternative for treatment of opioid overdose in the prehospital setting. J Emerg Med. 2005;29(3):265–71.

Article  PubMed  Google Scholar 

Dixon P. Managing acute heroin overdose. Emerg Nurse. 2007;15(2):30–5.

Article  PubMed  Google Scholar 

Kelly AM, Kerr D, Dietze P, Patrick I, Walker T, Koutsogiannis Z. Randomised trial of intranasal versus intramuscular naloxone in prehospital treatment for suspected opioid overdose. Med J Aust. 2005;182(1):24–7.

Article  PubMed  Google Scholar 

Kerr D, Dietze P, Kelly AM. Intranasal naloxone for the treatment of suspected heroin overdose. Addiction. 2008;103(3):379–86.

Article  PubMed  Google Scholar 

Clark AK, Wilder CM, Winstanley EL. A systematic review of community opioid overdose prevention and naloxone distribution programs. J Addict Med. 2014;8(3):153–63.

Article  CAS  PubMed  Google Scholar 

Keane C, Egan JE, Hawk M. Effects of naloxone distribution to likely bystanders: results of an agent-based model. Int J Drug Policy. 2018;55:61–9.

Article  PubMed  Google Scholar 

Walley AY, Xuan Z, Hackman HH, Quinn E, Doe-Simkins M, Sorensen-Alawad A, et al. Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis. BMJ. 2013;346: f174.

Article  PubMed  PubMed Central  Google Scholar 

Wheeler E, Jones TS, Gilbert MK, Davidson PJ, Centers for Disease C, Prevention. Opioid overdose prevention programs providing naloxone to laypersons - United States, 2014. MMWR Morb Mortal Wkly Rep. 2015;64(23):631–5.

PubMed  PubMed Central  Google Scholar 

Enteen L, Bauer J, McLean R, Wheeler E, Huriaux E, Kral AH, et al. Overdose prevention and naloxone prescription for opioid users in San Francisco. J Urban Health. 2010;87(6):931–41.

Article  PubMed  PubMed Central  Google Scholar 

Doe-Simkins M, Walley AY, Epstein A, Moyer P. Saved by the nose: bystander-administered intranasal naloxone hydrochloride for opioid overdose. Am J Public Health. 2009;99(5):788–91.

Article  PubMed  PubMed Central  Google Scholar 

Barocas JA, Baker L, Hull SJ, Stokes S, Westergaard RP. High uptake of naloxone-based overdose prevention training among previously incarcerated syringe-exchange program participants. Drug Alcohol Depend. 2015;154:283–6.

Article  PubMed  PubMed Central  Google Scholar 

Lambdin BH, Zibbell J, Wheeler E, Kral AH. Identifying gaps in the implementation of naloxone programs for laypersons in the United States. Int J Drug Policy. 2018;52:52–5.

Article  PubMed  Google Scholar 

Lambdin BH, Wenger L, Bluthenthal R, Bartholomew TS, Tookes HE, LaKosky P, et al. How do contextual factors influence naloxone distribution from syringe service programs in the USA: a cross-sectional study. Harm Reduct J. 2023;20(1):26.

Article  PubMed  PubMed Central  Google Scholar 

Lambdin BH, Davis CS, Wheeler E, Tueller S, Kral AH. Naloxone laws facilitate the establishment of overdose education and naloxone distribution programs in the United States. Drug Alcohol Depend. 2018;188:370–6.

Article  PubMed  Google Scholar 

Lambdin BH, Bluthenthal RN, Wenger LD, Wheeler E, Garner B, Lakosky P, et al. Overdose education and naloxone distribution within syringe service programs - United States, 2019. MMWR Morb Mortal Wkly Rep. 2020;69(33):1117–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kinnard EN, Bluthenthal RN, Kral AH, Wenger LD, Lambdin BH. The naloxone delivery cascade: identifying disparities in access to naloxone among people who inject drugs in Los Angeles and San Francisco. CA Drug Alcohol Depend. 2021;225:108759.

Article  PubMed  Google Scholar 

Weiner BJ, Lewis MA, Linnan LA. Using organization theory to understand the determinants of effective implementation of worksite health promotion programs. Health Educ Res. 2009;24(2):292–305.

Article  PubMed  Google Scholar 

Kirchner JE, Ritchie MJ, Pitcock JA, Parker LE, Curran GM, Fortney JC. Outcomes of a partnered facilitation strategy to implement primary care-mental health. J Gen Intern Med. 2014;29 Suppl 4(Suppl 4):904–12.

Article  PubMed  Google Scholar 

Kauth MR, Sullivan G, Blevins D, Cully JA, Landes RD, Said Q, et al. Employing external facilitation to implement cognitive behavioral therapy in VA clinics: a pilot study. Implement Sci. 2010;5:75.

Article  PubMed  PubMed Central  Google Scholar 

Kilbourne AM, Abraham KM, Goodrich DE, Bowersox NW, Almirall D, Lai Z, et al. Cluster randomized adaptive implementation trial comparing a standard versus enhanced implementation intervention to improve uptake of an effective re-engagement program for patients with serious mental illness. Implement Sci. 2013;8:136.

Article  PubMed  PubMed Central  Google Scholar 

Mignogna J, Hundt NE, Kauth MR, Kunik ME, Sorocco KH, Naik AD, et al. Implementing brief cognitive behavioral therapy in primary care: a pilot study. Transl Behav Med. 2014;4(2):175–83.

Article  PubMed  PubMed Central  Google Scholar 

Gustafson DH, Quanbeck AR, Robinson JM, Ford JH 2nd, Pulvermacher A, French MT, et al. Which elements of improvement collaboratives are most effective? A cluster-randomized trial. Addiction. 2013;108(6):1145–57.

Article  PubMed  PubMed Central  Google Scholar 

Williams L, Daggett V, Slaven JE, Yu Z, Sager D, Myers J, et al. A cluster-randomised quality improvement study to improve two inpatient stroke quality indicators. BMJ Qual Saf. 2016;25(4):257–64.

Article  PubMed  Google Scholar 

Kilbourne AM, Almirall D, Eisenberg D, Waxmonsky J, Goodrich DE, Fortney JC, et al. Protocol: Adaptive Implementation of Effective Programs Trial (ADEPT): cluster randomized SMART trial comparing a standard versus enhanced implementation strategy to improve outcomes of a mood disorders program. Implement Sci. 2014;9:132.

Article  PubMed  PubMed Central  Google Scholar 

Chinman M, McCarthy S, Hannah G, Byrne TH, Smelson DA. Using Getting To Outcomes to facilitate the use of an evidence-based practice in VA homeless programs: a cluster-randomized trial of an implementation support strategy. Implement Sci. 2017;12(1):34.

Article  PubMed  PubMed Central  Google Scholar 

Chinman M, Acosta J, Ebener P, Malone PS, Slaughter ME. Can implementation support help community-based settings better deliver evidence-based sexual health promotion programs? A randomized trial of Getting To Outcomes(R). Implement Sci. 2016;11(1):78.

Article  PubMed  PubMed Central  Google Scholar 

Jones J, Wyse R, Finch M, Lecathelinais C, Wiggers J, Marshall J, et al. Effectiveness of an intervention to facilitate the implementation of healthy eating and physical activity policies and practices in childcare services: a randomised controlled trial. Implement Sci. 2015;10:147.

Article  PubMed  PubMed Central  Google Scholar 

Seers K, Rycroft-Malone J, Cox K, Crichton N, Edwards RT, Eldh AC, et al. Facilitating Implementation of Research Evidence (FIRE): an international cluster randomised controlled trial to evaluate two models of facilitation informed by the Promoting Action on Research Implementation in Health Services (PARIHS) framework. Implement Sci. 2018;13(1):137.

Article  PubMed  PubMed Central