Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A Overview of the 2022 WHO Classification of Paragangliomas and Pheochromocytomas. Endocr Pathol 33: 90-114, 2022.

Article  CAS  PubMed  Google Scholar 

Miettinen M, McCue PA, Sarlomo-Rikala M et al. GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. Am J Surg Pathol 38: 13-22, 2014.

Article  PubMed  PubMed Central  Google Scholar 

Mamilla D, Manukyan I, Fetsch PA, Pacak K, Miettinen M Immunohistochemical distinction of paragangliomas from epithelial neuroendocrine tumors-gangliocytic duodenal and cauda equina paragangliomas align with epithelial neuroendocrine tumors. Hum Pathol 103: 72-82, 2020.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kimura N, Shiga K, Kaneko K, Sugisawa C, Katabami T, Naruse M The Diagnostic Dilemma of GATA3 Immunohistochemistry in Pheochromocytoma and Paraganglioma. Endocr Pathol 31: 95-100, 2020.

Article  CAS  PubMed  Google Scholar 

Mete O, Kefeli M, Caliskan S, Asa SL GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors. Mod Pathol 32: 484-489, 2019.

Article  CAS  PubMed  Google Scholar 

Uccella S, Facco C, Chiaravalli AM et al. Transcription Factor Expression in Sinonasal Neuroendocrine Neoplasms and Olfactory Neuroblastoma (ONB): Hyams' Grades 1-3 ONBs Expand the Spectrum of SATB2 and GATA3-Positive Neoplasms. Endocr Pathol 33: 264-273, 2022.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Soukup J, Manethova M, Kohout A et al. Cauda equina neuroendocrine tumors show biological features distinct from other paragangliomas and visceral neuroendocrine tumors. Virchows Arch, 2022.

Xu L, Yu G, Jiang L et al. HepPar1 and GATA-3 Expression in Neuroendocrine Neoplasms: A Potential Trap for Pathologic Diagnosis. Appl Immunohistochem Mol Morphol 31: 668-672, 2023.

Article  PubMed  Google Scholar 

Perrino CM, Ho A, Dall CP, Zynger DL Utility of GATA3 in the differential diagnosis of pheochromocytoma. Histopathology 71: 475-479, 2017.

Article  PubMed  Google Scholar 

Haraguchi T, Miyoshi H, Hiraoka K et al. GATA3 Expression Is a Poor Prognostic Factor in Soft Tissue Sarcomas. PLoS One 11: e0156524, 2016.

Article  PubMed  PubMed Central  Google Scholar 

Asa SL, Mete O Cytokeratin Profiles in Pituitary Neuroendocrine Tumors. Hum Pathol, 2020.

Manethova M, Gerykova L, Faistova H et al. Phox2B is a sensitive and reliable marker of paraganglioma-Phox2B immunohistochemistry in diagnosis of neuroendocrine neoplasms. Virchows Arch, 2023.

Miyauchi M, Akashi T, Furukawa A et al. PHOX2B is a Sensitive and Specific Marker for the Histopathological Diagnosis of Pheochromocytoma and Paraganglioma. Endocr Pathol, 2022.

Tamura M, Amano T, Shiroishi T The Hand2 gene dosage effect in developmental defects and human congenital disorders. Curr Top Dev Biol 110: 129-152, 2014.

Article  PubMed  Google Scholar 

Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K The role of Phox2B in chromaffin cell development. Dev Biol 279: 501-508, 2005.

Article  CAS  PubMed  Google Scholar 

Rohrer H Transcriptional control of differentiation and neurogenesis in autonomic ganglia. Eur J Neurosci 34: 1563-1573, 2011.

Article  PubMed  Google Scholar 

Unsicker K, Huber K, Schober A, Kalcheim C Resolved and open issues in chromaffin cell development. Mech Dev 130: 324-329, 2013.

Article  CAS  PubMed  Google Scholar 

Furlan A, Dyachuk V, Kastriti ME et al. Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science 357, 2017.

Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol 380: 286–298, 2013.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wildner H, Gierl MS, Strehle M, Pla P, Birchmeier C Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage. Development 135: 473-481, 2008.

Article  CAS  PubMed  Google Scholar 

Xu M, Sun M, Zhang X et al. HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype. Cancer Res 83: 686-699, 2023.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jones A, Teschendorff AE, Li Q et al. Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development. PLoS Med 10: e1001551, 2013.

Article  PubMed  PubMed Central  Google Scholar 

Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res 45: W98-W102, 2017.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Soukup J, Manethova M, Faistova H et al. Pitx2 is a useful marker of midgut-derived neuroendocrine tumours - an immunohistochemical study of 224 cases. Histopathology 81: 799-807, 2022.

Article  PubMed  Google Scholar 

Fedchenko N, Reifenrath J Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue - a review. Diagn Pathol 9: 221, 2014.

Article  PubMed  PubMed Central  Google Scholar 

Fishbein L, Leshchiner I, Walter V et al. Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma. Cancer Cell 31: 181-193, 2017.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne) 13: 1020000, 2022.

Morikawa Y, D'Autreaux F, Gershon MD, Cserjesi P Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Dev Biol 307: 114-126, 2007.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hockman D, Adameyko I, Kaucka M et al. Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol 444 Suppl 1: S308-S324, 2018.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee JP, Hung YP, O'Dorisio TM, Howe JR, Hornick JL, Bellizzi AM Examination of PHOX2B in adult neuroendocrine neoplasms reveals relatively frequent expression in phaeochromocytomas and paragangliomas. Histopathology 71: 503-510, 2017.

Article  PubMed  PubMed Central  Google Scholar 

Zethoven M, Martelotto L, Pattison A et al. Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment. Nat Commun 13: 6262, 2022.

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Ferguson CA, Firulli BA, Zoia M, Osterwalder M, Firulli AB Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs. Dev Dyn, 2023.

Voth H, Oberthuer A, Simon T, Kahlert Y, Berthold F, Fischer M Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. BMC Mol Biol 10: 28, 2009.

Article  PubMed  PubMed Central  Google Scholar 

Drabent P, Bonnard A, Guimiot F, Peuchmaur M, Berrebi D PHOX2B Immunostaining: A Simple and Helpful Tool for the Recognition of Ganglionic Cells and Diagnosis of Hirschsprung Disease. Am J Surg Pathol 44: 1389-1397, 2020.

Article  PubMed  Google Scholar