Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49. https://doi.org/10.3322/caac.21660.
Van Mechelen M, Van Herck A, Punie K, Nevelsteen I, Smeets A, Neven P, et al. Behavior of metastatic breast cancer according to subtype. Breast Cancer Res Treat. 2020;181:115–25. https://doi.org/10.1007/s10549-020-05597-3.
Article CAS PubMed Google Scholar
van Maaren MC, de Munck L, Strobbe LJA, Sonke GS, Westenend PJ, Smidt ML, et al. Ten-year recurrence rates for breast cancer subtypes in the Netherlands: a large population-based study. Int J Cancer. 2019;144:263–72. https://doi.org/10.1002/ijc.31914.
Article CAS PubMed Google Scholar
Welch DR, Hurst DR. Defining the hallmarks of metastasis. Cancer Res. 2019;79:3011–27. https://doi.org/10.1158/0008-5472.CAN-19-0458.
Article CAS PubMed PubMed Central Google Scholar
Ayob A, Ramasamy TS. Cancer stem cells as key drivers of tumour progression. J Biomed Sci. 2018;25:20. https://doi.org/10.1186/s12929-018-0426-4.
Article CAS PubMed PubMed Central Google Scholar
Babaei G, Aziz SGG, Jaghi NZZ. EMT, cancer stem cells and autophagy; the three main axes of metastasis. Biomed Pharmacother. 2021;133:110909. https://doi.org/10.1016/J.BIOPHA.2020.110909.
Article CAS PubMed Google Scholar
Wang D, Lu P, Zhang H, Luo M, Zhang X, Wei X, et al. Oct-4 and nanog promote the epithelial-mesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients. Oncotarget. 2014;5:10803–15. https://doi.org/10.18632/oncotarget.2506.
Article PubMed PubMed Central Google Scholar
Ayoub NM, Jaradat SK, Al-Shami KM, Alkhalifa AE. Targeting angiogenesis in breast cancer: current evidence and future perspectives of novel anti-angiogenic approaches. Front Pharmacol. 2022;13:838133. https://doi.org/10.3389/FPHAR.2022.838133/BIBTEX.
Article CAS PubMed PubMed Central Google Scholar
Fantozzi A, Gruber DC, Pisarsky L, Heck C, Kunita A, Yilmaz M, et al. VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation. Cancer Res. 2014;74:1566–75. https://doi.org/10.1158/0008-5472.CAN-13-1641.
Article CAS PubMed Google Scholar
Liu Y, Ma H, Yao J. ERα, a key target for cancer therapy: a review. Onco Targets ther. 2020;21:13:2183–91. https://doi.org/10.2147/OTT.S236532.
Deblois G, Giguère V. Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond. Nat Rev Cancer. 2013;13:27–36. https://doi.org/10.1038/NRC3396.
Article CAS PubMed Google Scholar
Manna S, Bostner J, Sun Y, Miller LD, Alayev A, Schwartz NS, et al. ERRα is a marker of tamoxifen response and survival in triple-negative breast cancer. Clin Cancer Res. 2016;22:1421–31. https://doi.org/10.1158/1078-0432.CCR-15-0857.
Article CAS PubMed Google Scholar
Ma JH, Qi J, Lin SQ, Zhang CY, Liu FY, Xie WD, et al. STAT3 targets ERRα to promote epithelial–mesenchymal transition, migration, and invasion in triple-negative breast cancer cells. Mol Cancer Res. 2019;17:2184–95. https://doi.org/10.1158/1541-7786.MCR-18-1194.
Article CAS PubMed Google Scholar
Suzuki T, Miki Y, Moriya T, Shimada N, Ishida T, Hirakawa H, et al. Estrogen-related receptor α in human breast carcinoma as a potent prognostic factor. Cancer Res. 2004;64:4670–76. https://doi.org/10.1158/0008-5472.CAN-04-0250.
Article CAS PubMed Google Scholar
Stein RA, Chang C, Kazmin DA, Way J, Schroeder T, Wergin M, et al. Estrogen-related receptor α is critical for the growth of estrogen receptor–negative breast cancer. Cancer Res. 2008;68:8805–12. https://doi.org/10.1158/0008-5472.CAN-08-1594.
Article CAS PubMed PubMed Central Google Scholar
Bianco S, Lanvin O, Tribollet V, Macari C, North S, Vanacker JM. Modulating estrogen receptor-related receptor-α activity inhibits cell proliferation. J Biol Chem. 2009;284:23286–92. https://doi.org/10.1074/JBC.M109.028191.
Article CAS PubMed PubMed Central Google Scholar
Wu YM, Chen ZJ, Liu H, Wei WD, Lu LL, Yang XL, et al. Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin. Oncotarget. 2015;6:25588–601. https://doi.org/10.18632/oncotarget.4436.
Article PubMed PubMed Central Google Scholar
Berman AY, Manna S, Schwartz NS, Katz YE, Sun Y, Behrmann CA, et al. ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism. Signal Transduct Target Ther. 2017;2:17035. https://doi.org/10.1038/sigtrans.2017.35.
Article PubMed PubMed Central Google Scholar
Naik M, Brahma P, Dixit M. A cost-effective and eefficient chick ex-ovo CAM assay protocol to assess angiogenesis. Methods Protoc. 2018;1:19. https://doi.org/10.3390/mps1020019.
Article CAS PubMed PubMed Central Google Scholar
Kue CS, Tan KY, Lam ML, Lee HB. Chick embryo chorioallantoic membrane (CAM): an alternative predictive model in acute toxicological studies for anti-cancer drugs. Exp Anim. 2015;64:129–38. https://doi.org/10.1538/expanim.14-0059.
Article CAS PubMed PubMed Central Google Scholar
The public health service responds to commonly asked questions. ILAR J. 1991;33(4):68–70. https://doi.org/10.1093/ilar.33.4.68.
Thomas D, Thiagarajan PS, Rai V, Reizes O, Lathia J, Egelhoff T. Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation. Oncotarget. 2016;7:47586–92. https://doi.org/10.18632/oncotarget.9896.
Article PubMed PubMed Central Google Scholar
Wu Y, Sarkissyan M, Vadgama J. Epithelial-mesenchymal transition and breast cancer. J Clin Med. 2016;5:13. https://doi.org/10.3390/jcm5020013.
Article CAS PubMed PubMed Central Google Scholar
Mani SA, Guo W, Liao M-J, Eaton ENg, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133:704–15. https://doi.org/10.1016/j.cell.2008.03.027.
Article CAS PubMed PubMed Central Google Scholar
Chen C, Zhao S, Karnad A, Freeman JW. The biology and role of CD44 in cancer progression: therapeutic implications. J Hematol Oncol. 2018;11:64. https://doi.org/10.1186/S13045-018-0605-5.
Article PubMed PubMed Central Google Scholar
Yang L, Shi P, Zhao G, Xu J, Peng W, Zhang J, et al. Targeting cancer stem cell pathways for cancer therapy. Signal Transduct Target Ther. 2020;5:8. https://doi.org/10.1038/s41392-020-0110-5.
Article CAS PubMed PubMed Central Google Scholar
Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature. 2010;468:824–8. https://doi.org/10.1038/nature09557.
Article ADS CAS PubMed Google Scholar
Xiong YQ, Sun HC, Zhang W, Zhu XD, Zhuang PY, Zhang JB, et al. Human hepatocellular carcinoma tumor–derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin Cancer Res. 2009;15:4838–46. https://doi.org/10.1158/1078-0432.CCR-08-2780.
Article CAS PubMed Google Scholar
Duan H, Liu Y, Gao Z, Huang W. Recent advances in drug delivery systems for targeting cancer stem cells. Acta Pharm Sin B. 2021;11:55–70. https://doi.org/10.1016/j.apsb.2020.09.016.
Article CAS PubMed Google Scholar
Muduli K, Prusty M, Pradhan J, Samal AP, Sahu B, Roy DS, et al. Estrogen-related receptor alpha (ERRα) promotes cancer stem cell-like characteristics in breast cancer. Stem Cell Rev Rep. 2023;19:2807–19. https://doi.org/10.1007/s12015-023-10605-2.
Article CAS PubMed Google Scholar
Croker AK, Goodale D, Chu J, Postenka C, Hedley BD, Hess DA, et al. High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. J Cell Mol Med. 2009;13:2236–52. https://doi.org/10.1111/j.1582-4934.2008.00455.x.
Li W, Ma H, Zhang J, Zhu L, Wang C, Yang Y. Unraveling the roles of CD44/CD24 and ALDH1 as cancer stem cell markers in tumorigenesis and metastasis. Sci Rep. 2017;7:13856. https://doi.org/10.1038/s41598-017-14364-2.
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