Department of Ophthalmology (B.S.-C., A.A., N.R., J.M., L.G., H.D., D.T., F.C.F.), Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Centro de Oftalmología Barraquer (B.S.-C., J.L.-M.), Instituto Universitario Barraquer, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Ophthalmology (D.T.), University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland; and Biosciences Institute (F.C.F.), Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

Address correspondence to Francisco C. Figueiredo, M.D., Ph.D., Department of Ophthalmology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle Upon Tyne NE1 4LP, United Kingdom; e-mail: [email protected]

The authors have no funding or conflicts of interest to disclose.

ARVO Annual Meeting, May 2019, Vancouver, Canada (poster); 19th Emirates Society of Ophthalmology Conference, February 2021, Dubai, UAE (online—oral communication); International CXL Experts' meeting, December 2021, Zurich, Switzerland (online—oral communication).

Concept and design (B. Salvador-Culla, F. C. Figueiredo); collection of data (B. Salvador-Culla, A. Afsara, D. Tabibian, L. Galankova, H. Duncan, J. Lamarca-Mateu); analysis and interpretation (B. Salvador-Culla, J. Lamarca-Mateu, F. C. Figueiredo); statistical analysis (B. Salvador-Culla, J. Lamarca-Mateu); manuscript preparation (B. Salvador-Culla, F. C. Figueiredo); critical revision of the manuscript (B. Salvador-Culla, J. Lamarca-Mateu, F. C. Figueiredo); and final approval of the manuscript (B. Salvador-Culla, A. Afsara, N. Roper, J. Mulroy, D. Tabibian, L. Galankova, H. Duncan, J. Lamarca-Mateu, F. C. Figueiredo).

All relevant data are within the paper and its Supporting Information files.