Giaquinto AN, Sung H, Miller KD, et al. Breast cancer statistics, 2022. CA Cancer J Clin. 2022;72:524–41.

Article  PubMed  Google Scholar 

Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Darby S, McGale P, Correa C, et al. EBCTCG Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet 2011;378:1707–1716.

Meattini I, Guenzi M, Fozza A, et al. Overview on cardiac, pulmonary and cutaneous toxicity in patients treated with adjuvant radiotherapy for breast cancer. Breast Cancer. 2017;24:52–62.

Article  PubMed  Google Scholar 

Darby SC, Ewertz M, McGale P, et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med. 2013;368:987–98.

Article  CAS  PubMed  Google Scholar 

Poortmans PMP, Arenas M, Livi L. Over-irradiation. Breast. 2017;31:295–302.

Article  PubMed  Google Scholar 

Hughes KS, Schnaper LA, Bellon JR, et al. Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343y. J Clin Oncol. 2013;31:2382–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kunkler IH, Williams LJ, Jack WJL, et al. Breast-conserving surgery with or without irradiation in early breast cancer. N Engl J Med. 2023;388:585–94.

Article  PubMed  Google Scholar 

Hepel JT, Wazer DE. Partial breast irradiation is the preferred standard of care for a majority of women with early-stage breast cancer. J Clin Oncol. 2020;38:2268–72.

Article  CAS  PubMed  Google Scholar 

Whelan TJ, Julian JA, Berrang TS, et al. External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial. Lancet. 2019;394:2165–72.

Article  PubMed  Google Scholar 

Vicini FA, Cecchini RS, White JR, et al. Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial. Lancet. 2019;394:2155–64.

Article  PubMed  PubMed Central  Google Scholar 

Coles CE, Griffin CL, Kirby AM, et al. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet. 2017;390:1048–60.

Article  PubMed  PubMed Central  Google Scholar 

Meattini I, Marrazzo L, Saieva C, et al. Accelerated partial-breast irradiation compared with whole-breast irradiation for early breast cancer: long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol. 2020;38:4175–83.

Article  PubMed  Google Scholar 

Polgár C, Major T, Takácsi-Nagy Z, et al. Breast-conserving surgery followed by partial or whole breast irradiation: twenty-year results of a phase 3 clinical study. Int J Radiat Oncol Biol Phys. 2021;109:998–1006.

Article  PubMed  Google Scholar 

Strnad V, Polgár C, Ott OJ, et al. Accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy compared with whole-breast irradiation with boost for early breast cancer: 10-year results of a GEC-ESTRO randomised, phase 3, non-inferiority trial. Lancet Oncol. 2023;24:262–72.

Article  CAS  PubMed  Google Scholar 

Hepel JT, Tokita M, MacAusland SG, et al. Toxicity of three-dimensional conformal radiotherapy for accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys. 2009;75:1290–6.

Article  PubMed  Google Scholar 

Sato K, Shimo T, Fuchikami H, et al. Predicting adherence of dose-volume constraints for personalized partial-breast irradiation technique. Brachytherapy. 2021;20:163–70.

Article  PubMed  Google Scholar 

Cozzi S, Laplana M, Najjari D, et al. Advantages of intraoperative implant for interstitial brachytherapy for accelerated partial breast irradiation either frail patients with early-stage disease or in locally recurrent breast cancer. J Contemp Brachyther. 2018;10:97–104.

Article  Google Scholar 

Sato K, Fuchikami H, Takeda N, et al. Efficacy of single-plane Implant technique in partial breast brachytherapy in small-breasted patients. Int J Radiat Oncol Biol Phys. 2020;106:830–7.

Article  CAS  PubMed  Google Scholar 

Sato K, Fuchikami H, Takeda N, et al. Moving incision for covert breast-conserving surgery may prevent early wound complications in brachytherapy-based partial-breast irradiation. Brachytherapy. 2019;18:645–50.

Article  PubMed  Google Scholar 

Tsujimoto M, Nakabayashi K, Yoshidome K, et al. One-step nucleic acid amplification for intraoperative detection of lymph node metastasis in breast cancer patients. Clin Cancer Res. 2007;13:4807–16.

Article  CAS  PubMed  Google Scholar 

National Cancer Institute, National Institutes of Health, US Department of Health and Human Services. Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/ctc.htm. Accessed 18 Sept 2023

Shah C, Jia X, Hobbs BP, et al. Outcomes with partial breast irradiation vs. whole breast irradiation: a meta-analysis. Ann Surg Oncol. 2021;28:4985–94.

Article  PubMed  Google Scholar 

Goldberg M, Bridhikitti J, Khan AJ, et al. A Meta-analysis of trials of partial breast irradiation. Int J Radiat Oncol Biol Phys. 2023;115:60–72.

Article  PubMed  Google Scholar 

Shumway DA, Corbin KS, Farah MH, et al. Partial breast irradiation compared with whole breast irradiation: a systematic review and meta-analysis. J Natl Cancer Inst. 2023;115:1011.

Article  PubMed  Google Scholar 

Meneveau MO, Petroni GR, Varhegyi NE, et al. Toxicity and cosmetic outcomes after treatment with a novel form of breast IORT. Brachytherapy. 2020;19:679–84.

Article  PubMed  PubMed Central  Google Scholar 

Hannoun-Lévi JM, Cham Kee DL, Gal J, et al. Accelerated partial breast irradiation for suitable elderly women using a single fraction of multicatheter interstitial high-dose-rate brachytherapy: early results of the single-fraction elderly breast irradiation (SiFEBI) phase I/II trial. Brachytherapy. 2018;17:407–14.

Article  PubMed  Google Scholar 

Hannoun-Lévi JM, Lam Cham KD, Gal J, et al. Accelerated partial breast irradiation in the elderly: 5-year results of the single fraction elderly breast irradiation (SiFEBI) phase I/II trial. Brachytherapy. 2020;19:90–6.

Article  PubMed  Google Scholar 

Jethwa KR, Park SS, Gonuguntla K, et al. Three-fraction intra-cavitary accelerated partial breast brachytherapy: early provider and patient-reported outcomes of a novel regimen. Int J Radiat Oncol Biol Phys. 2019;104:75–82.

Article  PubMed  Google Scholar 

Chung EM, Nguyen AT, Mirhadi A, et al. A single-institution retrospective study of three-fraction HDR accelerated partial breast irradiation. Brachytherapy. 2023;22:361–7.

Article  PubMed  Google Scholar 

Khan AJ, Chen PY, Yashar C, et al. Three-fraction accelerated partial breast irradiation (APBI) delivered with brachytherapy applicators is feasible and safe: first results from the TRIUMPH-T Trial. Int J Radiat Oncol Biol Phys. 2019;104:67–74.

Article  PubMed  PubMed Central  Google Scholar 

Guinot JL, Gonzalez-Perez V, Meszaros N, et al. Very accelerated partial breast irradiation phase I-II multicenter trial (VAPBI): feasibility and early results. Brachytherapy. 2021;20:332–8.

Article  PubMed  Google Scholar 

Wilkinson JB, Chen PY, Wallace MF, et al. Six-year results from a phase I/II trial for hypofractionated accelerated partial breast irradiation using a 2-day dose schedule. Am J Clin Oncol. 2018;41:986–91.

Article  PubMed  Google Scholar 

Morales MG, Martínez-Monge R, Martínez-Regueira F, et al. Four-fraction ultra-accelerated minimal breast irradiation in early breast cancer: the initial feasibility results of an institutional experience. Brachytherapy. 2022;21:475–86.

Article  PubMed  Google Scholar 

Silverstein MJ, Kim B, Lin K, et al. Risk-adapted intraoperative radiation therapy (IORT) for breast cancer: a novel analysis. Ann Surg Oncol. 2023;30:6079.

Article  PubMed  PubMed Central  Google Scholar