Hepatotoxic Effect of Hydrogen Cyanamide (Dormex®) in Albino Rats and the Ameliorative Effect of Melatonin

-Oreby, M.M, Elgazzar, F.M, Hassab El-Nabi, S.E, Ali, D.A. The toxic effect of cyanamide (dormex) on testis in albino rats: Possible protective role of selenium, Egypt J. Forensic Sci. Appli. Toxicol 2015; 15 (2).

-Foti C, Bonamonte D, Conserva A, et al. Allergic contact dermatitis with a fertilizer containing hydrogen cyanamide (Dormex). Cutaneous and ocular toxicology,2008; 27(1):1–3.

-El Mahdy, N.M and Kharoub, H.S. Acute toxicity due to occupational exposure to the plant growth regulator hydrogen cyanamide (case report), Egyptian Journal of Occupational Medicine,2020; 44 (1): 471 - 484 https://doi.org/10.21608/ejom.2020.67632

-Schep L, Temple W and Beasley M. The adverse effects of hydrogen cyanamide on human health: an evaluation of inquiries to the New Zealand National Poisons Centre. Clinical toxicology (Philadelphia, Pa.),2009;47(1):58–60.

-El Masry M, Osman H and Hady A. Cyanamide toxicity. Role of alpha tocopherol antioxidant. New Egyptian journal of medicine.2000;Available at: https://www.researchgate.net/publication/232088361

-Settimi L, Davanzo F, Travaglia A, et al. Italian program for surveillance of acute pesticide-related illnesses: cases identified in 2005. Giornale italiano di medicina del lavoro ed ergonomia,2007; 29(3): 264–266.

-Gamaluddin H, Mahmmoud S, Mosa M, et al. A clinical study of acute hydrogen cyanamide toxicity in the period between 2006-2009 in the poison control center, Ain Shams University. Ain Shams Journal of Forensic Medicine and Clinical Toxicology,2012; 19:97–103.

-Sharif AF and Fayed MM. Evaluation of multiple organ dysfunction score (MODS) and the sequential organ failure assessment (SOFA) score as in-hospital outcome predictors among cases of hydrogen cyanamide exposure: a cross-sectional study. Environmental science and pollution research international,2021; 28(31):42161-42176

-Fernández-Gil, A. E. A. Moneim, F. Ortiz et al. Melatonin protects rats from radiotherapy-induced small intestine toxicity, PLoS One, 2017; 12, 4, article e0174474.

-S. Dutta, S. Saha, S. Mahalanobish, P. Sadhukhan, and P. C. Sil. Melatonin attenuates arsenic induced nephropathy via the regulation of oxidative stress and inflammatory signaling cascades in mice,” Food and Chemical Toxicology,2018; 118, 303–316 .

-Manchester, L.C.; Coto-Montes, A.; Boga, J.A.; Andersen, L.P.H.; Zhou, Z.; Galano, A.; Vriend, J.; Tan, D.X.; Reiter, R.J. Melatonin: An ancient molecule that makes oxygen metabolically tolerable. J. Pineal Res. ,2015; 59,403–419.

-Bali, I.; Bilir, B.; Emir, S.; Turan, F.; Yilmaz, A.; Gokkus, T.; Aydin, M. The effects of melatonin on liver functions in arsenic-induced liver damage. Turk. J. Surg. ,2016; 32, 233–237.

-Reiter, R.J.; Mayo, J.C.; Tan, D.-X.; Sainz, R.M.; Alatorre-Jimenez, M.; Qin, L. Melatonin as an Antioxidant: Under Promises but over Delivers. J. Pineal Res. ,2016 ; 61, 253–278.

-Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993 Nov;123(11):1939-51.

-Koksal M, Kurcer Z, Erdogan D, Iraz M, Tas M,Eren MA, et al. Effect of melatonin and nacetylcysteine on hepatic injury in rat induced by methanol intoxication: A comparative study. Eur Rev Med Pharmacol Sci, 2012;16(4):437-44

-Kaplan M, Atakan IH, Aydoğdu N, Aktoz T, Puyan, FO, Şeren G, et al. The effect of melatonin on cadmium-induced renal injury in chronically exposed rats. Turk J Urol. 2009;35(2):139-47

-Abdou KA and Abo El-Atta HM. Epidemiology of pesticides in developing countries. Adv Clin Toxicol;2018; 3(1): 1-8.

-Elhosary, N., Elgharbawy, D.E., Kassab, A. and Elgharabawy, R.M. Cyanamide-induced hepatotoxicity and the potential protective role of pomegranate seed extract in adult male albino rats. Ain Shams Journal of Forensic Medicine and Clinical Toxicology,2018; 30(1), 38-51.

-Elbastawesy, S., Ibrahim, F., Abo Safia, H., El Shamy, A., Ibrahim, H. and Helal, N. Nephrotoxic effect of hydrogen cyanamide (dormex) and possible protective role of n-acetyl cysteine in male albino rats. Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2022; 39(2),21-29.

-Oleshchuk, O., Ivankiv, Y., Falfushynska, H., Mudra, A. and Lisnychuk, N. Hepatoprotective effect of melatonin in toxic liver injury in rats. Medicina,2019; 55(6), 304.

-Othman, M.S., Fareid, M.A., Abdel Hameed, R.S. and Abdel Moneim, A.E. The protective effects of melatonin on aluminum-induced hepatotoxicity and nephrotoxicity in rats. Oxidative Medicine and Cellular Longevity, 2020. Article ID 7375136, 12 pages .https://doi.org/10.1155/2020/7375136

-Ferlazzo, N.; Andolina, G.; Cannata, A.; Costanzo, M.G.; Rizzo, V.; Currò, M.; Ientile, R.; Caccamo, D. Is melatonin the cornucopia of the 21st century? Antioxidants ,2020; 9, 1088.

-Rosen HR and Keeffe HR. Evaluation of abnormal liver enzymes, use of liver test and the serology of viral hepatitis. In: Liver disease diagnosis and management. Bacon br and Bisceglie am (eds), Churchill Livingstone, New York.2000; 24–35.

-Saxena B and Sharma S. Food color induced hepatotoxicity in Swiss albino rats. Rattus norvegicus. Toxicol. Int. 2015; 22 (1):152–157.

-Sayan M, Karabulut D, Özdamar S. Assessment of the protective and therapeutic effect of melatonin against thioacetamide‐induced acute liver damage. J Biochem Mol Toxicol. 2020;e22450.

-Lemieux, I., Pascot, A., Couillard, C., Lamarche, B., Tchernof, A., Alméras, N., Bergeron, J., Gaudet, D., Tremblay, G., Prud’homme, D. and Nadeau, A. Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?. Circulation,2000; 102(2), 179-184.

-Koziróg, M., Poliwczak, A.R., Duchnowicz, P., Koter‐Michalak, M., Sikora, J. and Broncel, M. Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. Journal of pineal research, 2011;50(3), 261-266. https://doi.org/10.1002/jbt.22450

留言 (0)

沒有登入
gif