Chanson P, Maiter D. The epidemiology, diagnosis and treatment of prolactinomas: the old and the new. Best Pract Res Clin Endocrinol Metab. 2019;33(2):101290. https://doi.org/10.1016/j.beem.2019.101290 PMID:31326373 DOI: https://doi.org/10.1016/j.beem.2019.101290

Vroonen L, Daly AF, Beckers A. Epidemiology and management challenges in prolactinomas. Neuroendocrinology. 2019;109(1):20-27. https://doi.org/10.1159/000497746 PMID:30731464 DOI: https://doi.org/10.1159/000497746

Olarescu NC, Perez-Rivas LG, Gatto F, et al; EYRC (ENEA Young Researcher Committee). Aggressive and Malignant Prolactinomas. Neuroendocrinology. 2019;109(1):57-69. https://doi.org/10.1159/000497205 PMID:30677777 DOI: https://doi.org/10.1159/000497205

de Laat JM, Dekkers OM, Pieterman CR, et al. Long-term natural course of pituitary tumors in patients with MEN1: results from the Dutch MEN1 study group (DMSG). J Clin Endocrinol Metab. 2015;100(9):3288-3296. https://doi.org/10.1210/JC.2015-2015 PMID:26126205 DOI: https://doi.org/10.1210/JC.2015-2015

Daly AF, Tichomirowa MA, Petrossians P, et al. Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study. J Clin Endocrinol Metab. 2010;95(11):E373-E383. https://doi.org/10.1210/jc.2009-2556 PMID:20685857 DOI: https://doi.org/10.1210/jc.2009-2556

Soto-Pedre E, Newey PJ, Bevan JS, Leese GP. Morbidity and mortality in patients with hyperprolactinaemia: the PROLEARS study. Endocr Connect. 2017;6(8):580-588. https://doi.org/10.1530/EC-17-0171 PMID:28954743 DOI: https://doi.org/10.1530/EC-17-0171

Iannone P, Coclite D, Fauci AJ, Graziano G, Napoletano AM. [Italian guidelines in accordance with the new National Guidelines System: critical issues and perspectives]. Recenti Prog Med. 2017;108(9):360-362. https://doi.org/10.1701/2745.27986 PMID:28901343

Morgano GP, Parmelli E, Amato L, et al. [GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines]. Recenti Prog Med. 2018;109(5):272-293. https://doi.org/10.1701/2902.29246 PMID:29771250

Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(2):273-288. https://doi.org/10.1210/jc.2010-1692 PMID:21296991 DOI: https://doi.org/10.1210/jc.2010-1692

Sistema Nazionale Linee Guida dell’Istituto Superiore di Sanità. Terapia dei prolattinomi. 2022. https://www.iss.it/documents/20126/8403889/LG188-AME_Terapia-prolattinomi.pdf/307919a6-d35b-b5b7-ec4c-8afc4a5eb093?t=1678805522649 (Accessed April 2023)

Verhelst J, Abs R, Maiter D, et al. Cabergoline in the treatment of hyperprolactinemia: a study in 455 patients. J Clin Endocrinol Metab. 1999;84(7):2518-2522. https://doi.org/10.1210/jcem.84.7.5810 PMID:10404830 DOI: https://doi.org/10.1210/jcem.84.7.5810

Colao A, Di Sarno A, Landi ML, et al. Macroprolactinoma shrinkage during cabergoline treatment is greater in naive patients than in patients pretreated with other dopamine agonists: a prospective study in 110 patients. J Clin Endocrinol Metab. 2000;85(6):2247-2252. https://doi.org/10.1210/jcem.85.6.6657 PMID:10852458 DOI: https://doi.org/10.1210/jc.85.6.2247

Casanueva FF, Molitch ME, Schlechte JA, et al. Guidelines of the Pituitary Society for the diagnosis and management of prolactinomas. Clin Endocrinol (Oxf). 2006;65(2):265-273. https://doi.org/10.1111/j.1365-2265.2006.02562.x PMID:16886971 DOI: https://doi.org/10.1111/j.1365-2265.2006.02562.x

Cozzi R, Ambrosio MR, Attanasio R, et al. Italian Association of Clinical Endocrinologists (AME) and International Chapter of Clinical Endocrinology (ICCE). Position statement for clinical practice: prolactin-secreting tumors. Eur J Endocrinol. 2022;186(3):1-P33. https://doi.org/10.1530/EJE-21-0977 PMID:35000899 DOI: https://doi.org/10.1530/EJE-21-0977

Molitch ME. Dopamine resistance of prolactinomas. Pituitary. 2003;6(1):19-27. https://doi.org/10.1023/A:1026225625897 PMID:14674720 DOI: https://doi.org/10.1023/A:1026225625897

Maiter D. Management of dopamine agonist-resistant prolactinoma. Neuroendocrinology. 2019;109(1):42-50. https://doi.org/10.1159/000495775 PMID:30481756 DOI: https://doi.org/10.1159/000495775

Colao A, Di Sarno A, Cappabianca P, Di Somma C, Pivonello R, Lombardi G. Withdrawal of long-term cabergoline therapy for tumoral and nontumoral hyperprolactinemia. N Engl J Med. 2003;349(21):2023-2033. https://doi.org/10.1056/NEJMoa022657 PMID:14627787 DOI: https://doi.org/10.1056/NEJMoa022657

Zamanipoor Najafabadi AH, Zandbergen IM, de Vries F, et al. Surgery as a viable alternative first-line treatment for prolactinoma patients. A systematic review and meta-analysis. J Clin Endocrinol Metab. 2020;105(3):e32-e41. https://doi.org/10.1210/clinem/dgz144 PMID:31665485 DOI: https://doi.org/10.1210/clinem/dgz144

Tampourlou M, Trifanescu R, Paluzzi A, Ahmed SK, Karavitaki N. Therapy of endocrine disease: surgery in microprolactinomas: effectiveness and risks based on contemporary literature. Eur J Endocrinol. 2016;175(3):R89-R96. https://doi.org/10.1530/EJE-16-0087 PMID:27207245 DOI: https://doi.org/10.1530/EJE-16-0087

Roelfsema F, Biermasz NR, Pereira AM. Clinical factors involved in the recurrence of pituitary adenomas after surgical remission: a structured review and meta-analysis. Pituitary. 2012;15(1):71-83. https://doi.org/10.1007/s11102-011-0347-7 PMID:21918830 DOI: https://doi.org/10.1007/s11102-011-0347-7

Primeau V, Raftopoulos C, Maiter D. Outcomes of transsphenoidal surgery in prolactinomas: improvement of hormonal control in dopamine agonist-resistant patients. Eur J Endocrinol. 2012;166(5):779-786. https://doi.org/10.1530/EJE-11-1000 PMID:22301915 DOI: https://doi.org/10.1530/EJE-11-1000

Sheplan Olsen LJ, Robles Irizarry L, Chao ST, et al. Radiotherapy for prolactin-secreting pituitary tumors. Pituitary. 2012;15(2):135-145. https://doi.org/10.1007/s11102-011-0348-6 PMID:21948464 DOI: https://doi.org/10.1007/s11102-011-0348-6

Hung YC, Lee CC, Yang HC, et al. The benefit and risk of stereotactic radiosurgery for prolactinomas: an international multicenter cohort study. J Neurosurg. 2019;133(3):1-10. https://doi.org/10.3171/2019.4.JNS183443 PMID:31374549 DOI: https://doi.org/10.3171/2020.12.JNS183443a

Trouillas J, Delgrange E, Wierinckx A, et al. Clinical, pathological, and molecular factors of aggressiveness in lactotroph tumours. Neuroendocrinology. 2019;109(1):70-76. https://doi.org/10.1159/000499382 PMID:30943495 DOI: https://doi.org/10.1159/000499382

McCormack A, Dekkers OM, Petersenn S, et al; ESE Survey Collaborators. Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016. Eur J Endocrinol. 2018;178(3):265-276. https://doi.org/10.1530/EJE-17-0933 PMID:29330228 DOI: https://doi.org/10.1530/EJE-17-0933

Drummond MF, Sculpher MJ, Claxton K, et al. Methods for the economic evaluation of health care programmes. 4th ed. Oxford University Press; 2015:253-255.

Perazzo H, Jorge MJ, Silva JC, et al. Micro-costing analysis of guideline-based treatment by direct-acting agents: the real-life case of hepatitis C management in Brazil. BMC Gastroenterol. 2017;17(1):119. https://doi.org/10.1186/s12876-017-0676-8 PMID:29169329 DOI: https://doi.org/10.1186/s12876-017-0676-8

Edwards RT, Céilleachair A, Bywater T, Hughes DA, Hutchings J. Parenting programme for parents of children at risk of developing conduct disorder: cost effectiveness analysis. BMJ. 2007;334(7595):682. https://doi.org/10.1136/bmj.39126.699421.55 PMID:17350965 DOI: https://doi.org/10.1136/bmj.39126.699421.55

Griffith GL, Edwards RT, Gray J, et al. Estimating the survival benefits gained from providing national cancer genetic services to women with a family history of breast cancer. Br J Cancer. 2004;90(10):1912-1919. https://doi.org/10.1038/sj.bjc.6601794 PMID:15138471 DOI: https://doi.org/10.1038/sj.bjc.6601794

Kinsella S. Ten lessons for micro-costing in health economics. Department of Economics, Kemmy Business School, University of Limerick; 2008.

Morris S, Devlin N, Parkin D, Spencer A. Economic analysis in healthcare. John Wiley & Sons; 2012.

Fattore G. Proposta di Linee Guida per la valutazione economica degli interventi sanitari in Italia. PharmacoEcon Ital Res Artic. 2009;11(2):83-93. https://doi.org/10.1007/BF03320660 DOI: https://doi.org/10.1007/BF03320660

Ministero della Salute M. Tariffario delle Prestazioni Specialistiche Ambulatoriali. http://www.salute.gov.it/portale/temi/p2_6.jsp?id=1767&area=programmazioneSanitariaLea&menu=lea. Accessed July 2023.

Agenzia per la Rappresentanza Negoziale delle Pubbliche Amministrazioni (ARAN). https://www.aranagenzia.it/statistiche-e-pubblicazioni/dati-statistici.html. Accessed July 2023.

Agenzia Italiana del Farmaco (AIFA). Lista di Trasparenza AIFA, Farmaci di Fascia H. https://www.aifa.gov.it/liste-farmaci-a-h. Accessed July 2023.

Agenzia Italiana del Farmaco (AIFA). Lista di Trasparenza AIFA, Farmaci di Fascia A. https://www.aifa.gov.it/liste-farmaci-a-h. Accessed July 2023.

Jethwa PR, Patel TD, Hajart AF, Eloy JA, Couldwell WT, Liu JK. Cost-effectiveness analysis of microscopic and endoscopic transsphenoidal surgery versus medical therapy in the management of microprolactinoma in the United States. World Neurosurg. 2016;87:65-76. https://doi.org/10.1016/j.wneu.2015.10.090 PMID:26548828 DOI: https://doi.org/10.1016/j.wneu.2015.10.090

Russo P, Zanuzzi M, Carletto A, Sammarco A, Romano F, Manca A. Role of economic evaluations on pricing of medicines reimbursed by the Italian National Health Service. PharmacoEconomics. 2023;41(1):107-117. https://doi.org/10.1007/s40273-022-01215-w PMID:36434415 DOI: https://doi.org/10.1007/s40273-022-01215-w

Gray AM, Clarke PM, Wolstenholme JL, Wordsworth S. Applied methods of cost-effectiveness analysis in healthcare. Vol 3. Oxford: OUP; 2010.

Baussart B, Villa C, Jouinot A, et al. Pituitary surgery as alternative to dopamine agonists treatment for microprolactinomas: a cohort study. Eur J Endocrinol. 2021;185(6):783-791. https://doi.org/10.1530/EJE-21-0293 PMID:34605772 DOI: https://doi.org/10.1530/EJE-21-0293

Casanueva FF, Barkan AL, Buchfelder M, et al; Pituitary Society, Expert Group on Pituitary Tumors. Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement. Pituitary. 2017;20(5):489-498. https://doi.org/10.1007/s11102-017-0838-2 PMID:28884415 DOI: https://doi.org/10.1007/s11102-017-0838-2

Losa M, Mortini P, Barzaghi R, Gioia L, Giovanelli M. Surgical treatment of prolactin-secreting pituitary adenomas: early results and long-term outcome. J Clin Endocrinol Metab. 2002;87(7):3180-3186. https://doi.org/10.1210/jcem.87.7.8645 PMID:12107221 DOI: https://doi.org/10.1210/jcem.87.7.8645