Club cell protein (CC16) in serum as an effect marker for small airway epithelial damage caused by diesel exhaust and blasting fumes in potash mining

Backé E, Lotz G, Tittelbach U, Plitzko S, Gierke E, Schneider WD (2004) Immunological biomarkers in salt miners exposed to salt dust, diesel exhaust and nitrogen oxides. Int Arch Occup Environ Health 77(5):319–327. https://doi.org/10.1007/s00420-004-0521-6

Article  CAS  Google Scholar 

Biagioni BJ, Tam S, Chen Y-WR, Sin DD, Carlsten C (2016) Effect of controlled human exposure to diesel exhaust and allergen on airway surfactant protein D, myeloperoxidase and club (Clara) cell secretory protein 16. Clin Exp Allergy J Br Soc Allergy Clin Immunol 46(9):1206–1213. https://doi.org/10.1111/cea.12732

Article  CAS  Google Scholar 

Blomberg A, Mudway I, Svensson M, Hagenbjörk-Gustafsson A, Thomasson L, Helleday R, Dumont X, Forsberg B, Nordberg G, Bernard A (2003) Clara cell protein as a biomarker for ozone-induced lung injury in humans. Eur Respir J 22(6):883–888. https://doi.org/10.1183/09031936.03.00048203

Article  CAS  Google Scholar 

BMAS Federal Ministry of Labour and Social Affairs (2023) [online document in German] TRGS 900 Arbeitsplatzgrenzwerte, zuletzt geändert und ergänzt: GMBL 2023, S. 755-756 [Nr. 35] (vom 12.06.2023). https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRGS/TRGS-900.html. Accessed 15 Aug 2023

Boukelia B, Fogarty MC, Davison RCR, Florida-James GD (2017) Diurnal physiological and immunological responses to a 10-km run in highly trained athletes in an environmentally controlled condition of 6 °C. Eur J Appl Physiol 117(1):1–6. https://doi.org/10.1007/s00421-016-3489-5

Article  Google Scholar 

Boukelia B, Gomes EC, Florida-James GD (2018) Diurnal variation in physiological and immune responses to endurance sport in highly trained runners in a hot and humid environment. Oxid Med Cell Longev 2018:3402143. https://doi.org/10.1155/2018/3402143

Article  CAS  Google Scholar 

Broeckaert F, Clippe A, Knoops B, Hermans C, Bernard A (2000) Clara cell secretory protein (CC16): features as a peripheral lung biomarker. Ann N Y Acad Sci 923:68–77. https://doi.org/10.1111/j.1749-6632.2000.tb05520.x

Article  CAS  Google Scholar 

Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MWY, Crystal RG (2013) Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression. Hum Mol Genet 22(23):4726–4738. https://doi.org/10.1093/hmg/ddt326

Article  CAS  Google Scholar 

Dahmann D, Monz C, Sönksen H (2007) Exposure assessment in German potash mining. Int Arch Occup Environ Health 81(1):95–107. https://doi.org/10.1007/s00420-007-0194-z

Article  CAS  Google Scholar 

Doyle IR, Hermans C, Bernard A, Nicholas TE, Bersten AD (1998) Clearance of Clara cell secretory protein 16 (CC16) and surfactant proteins A and B from blood in acute respiratory failure. Am J Respir Crit Care Med 158(5 Pt 1):1528–1535. https://doi.org/10.1164/ajrccm.158.5.9712097

Article  CAS  Google Scholar 

Gamrad-Streubel L, Haase L-M, Rudolph KK, Rühle K, Bachand AM, Crawford L, Mundt KA, Bünger J, Pallapies D, Taeger D, Casjens S, Molkenthin A, Neumann S, Giesen J, Neumann V, Brüning T, Birk T (2022) Underground salt and potash workers exposed to nitrogen oxides and diesel exhaust: assessment of specific effect biomarkers. Int Arch Occup Environ Health. https://doi.org/10.1007/s00420-022-01876-2

Article  Google Scholar 

Gibbs J, Ince L, Matthews L, Mei J, Bell T, Yang N, Saer B, Begley N, Poolman T, Pariollaud M, Farrow S, DeMayo F, Hussell T, Worthen GS, Ray D, Loudon A (2014) An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action. Nat Med 20(8):919–926. https://doi.org/10.1038/nm.3599

Article  CAS  Google Scholar 

Guerra S, Halonen M, Vasquez MM, Spangenberg A, Stern DA, Morgan WJ, Wright AL, Lavi I, Tarès L, Carsin A-E, Dobaño C, Barreiro E, Zock J-P, Martínez-Moratalla J, Urrutia I, Sunyer J, Keidel D, Imboden M, Probst-Hensch N, Hallberg J, Melén E, Wickman M, Bousquet J, Belgrave DCM, Simpson A, Custovic A, Antó JM, Martinez FD (2015) Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med 3(8):613–620. https://doi.org/10.1016/S2213-2600(15)00196-4

Article  CAS  Google Scholar 

Helleday R, Segerstedt B, Forsberg B, Mudway I, Nordberg G, Bernard A, Blomberg A (2006) Exploring the time dependence of serum clara cell protein as a biomarker of pulmonary injury in humans. Chest 130(3):672–675. https://doi.org/10.1378/chest.130.3.672

Article  Google Scholar 

Hung C-H, Chen L-C, Zhang Z, Chowdhury B, Lee W-L, Plunkett B, Chen C-H, Myers AC, Huang S-K (2004) Regulation of TH2 responses by the pulmonary Clara cell secretory 10-kd protein. J Allergy Clin Immunol 114(3):664–670. https://doi.org/10.1016/j.jaci.2004.05.042

Article  CAS  Google Scholar 

Ince LM, Zhang Z, Beesley S, Vonslow RM, Saer BR, Matthews LC, Begley N, Gibbs JE, Ray DW, Loudon ASI (2019) Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells. FASEB J off Publ Fed Am Soc Exp Biol 33(1):126–139. https://doi.org/10.1096/fj.201800026RR

Article  CAS  Google Scholar 

Krakowiak A, Hałatek T, Nowakowska-Świrta E, Winnicka R, Politański P, Świderska-Kiełbik S (2013) Clara Cell protein and myeloperoxidase levels in serum of subjects after exposure to fire smoke. Pneumonol Alergol Pol 81(1):16–23

CAS  Google Scholar 

Lakind JS, Holgate ST, Ownby DR, Mansur AH, Helms PJ, Pyatt D, Hays SM (2007) A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects. Biomark Biochem Biomark Expo Response Susceptibility Chem 12(5):445–467. https://doi.org/10.1080/13547500701359327

Article  CAS  Google Scholar 

Latza U (ed) (2005), [Book in German], Erhebung, Quantifizierung und Analyse der Rauchexposition in epidemiologischen Studien. Robert Koch-Institut, Berlin: ISBN 3-89606-090-2. https://www.rki.de/DE/Content/Gesundheitsmonitoring/Themen/Rauchen/Rauchexposition_epidstudien.pdf%3F__blob%3DpublicationFile

Laucho-Contreras ME, Polverino F, Rojas-Quintero J, Wang X, Owen CA (2018) Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice. Physiol Rep 6(15):e13797. https://doi.org/10.14814/phy2.13797

Article  CAS  Google Scholar 

Li X-X, Peng T, Gao J, Feng J-G, Wu D-D, Yang T, Zhong L, Fu W-P, Sun C (2019) Allele-specific expression identified rs2509956 as a novel long-distance cis-regulatory SNP for SCGB1A1, an important gene for multiple pulmonary diseases. Am J Physiol Lung Cell Mol Physiol 317(4):L456–L463. https://doi.org/10.1152/ajplung.00275.2018

Article  CAS  Google Scholar 

Lotz G, Plitzko S, Gierke E, Tittelbach U, Kersten N, Schneider WD (2008) Dose-response relationships between occupational exposure to potash, diesel exhaust and nitrogen oxides and lung function: cross-sectional and longitudinal study in two salt mines. Int Arch Occup Environ Health 81(8):1003–1019. https://doi.org/10.1007/s00420-007-0294-9

Article  CAS  Google Scholar 

Lotz A, Kendzia B, Gawrych K, Lehnert M, Brüning T, Pesch B (2013) Statistical methods for the analysis of left-censored variables. GMS Medizinische Informatik, Biometrie Und Epidemiologie 9(2):Doc05 (Article in German)

Google Scholar 

Michel O, Murdoch R, Bernard A (2005) Inhaled LPS induces blood release of Clara cell specific protein (CC16) in human beings. J Allergy Clin Immunol 115(6):1143–1147. https://doi.org/10.1016/j.jaci.2005.01.067

Article  CAS  Google Scholar 

Stenberg H, Wadelius E, Moitra S, Åberg I, Ankerst J, Diamant Z, Bjermer L, Tufvesson E (2018) Club cell protein (CC16) in plasma, bronchial brushes, BAL and urine following an inhaled allergen challenge in allergic asthmatics. Biomarkers Biochem Indic Expo Response Susceptibility Chem 23(1):51–60. https://doi.org/10.1080/1354750X.2017.1375559

Article  CAS  Google Scholar 

Tafuro F, Selis L, Goldoni M, Stendardo M, Mozzoni P, Ridolo E, Boschetto P, Corradi M (2018) Biomarkers of respiratory allergy in laboratory animal care workers: an observational study. Int Arch Occup Environ Health 91(6):735–744. https://doi.org/10.1007/s00420-018-1321-8

Article  CAS  Google Scholar 

van Kampen V, Hoffmeyer F, Monsé C, Raulf M, Brüning T, Bünger J, Sucker K (2020) Discrimination between atopic, allergic, and asthmatic volunteers for human exposure studies on sensory irritation. Adv Exp Med Biol. https://doi.org/10.1007/5584_2020_520

Article  Google Scholar 

Wang G, Lou HH, Salit J, Leopold PL, Driscoll S, Schymeinsky J, Quast K, Visvanathan S, Fine JS, Thomas MJ, Crystal RG (2019a) Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity. Respir Res 20(1):196. https://doi.org/10.1186/s12931-019-1140-9

Article  CAS  Google Scholar 

Wang N, Li Q, Liu H, Lin L, Han W, Hao W (2019b) Role of C/EBPα hypermethylation in diesel engine exhaust exposure-induced lung inflammation. Ecotoxicol Environ Saf 183:109500. https://doi.org/10.1016/j.ecoenv.2019.109500

Article  CAS  Google Scholar 

Xu Y, Barregard L, Nielsen J, Gudmundsson A, Wierzbicka A, Axmon A, Jönsson BAG, Kåredal M, Albin M (2013) Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study. Part Fibre Toxicol 10:60. https://doi.org/10.1186/1743-8977-10-60

Article  CAS  Google Scholar 

Zhu L, Di PYP, Wu R, Pinkerton KE, Chen Y (2015) Repression of CC16 by cigarette smoke (CS) exposure. PLoS One 10(1):e0116159. https://doi.org/10.1371/journal.pone.0116159

Article  CAS  Google Scholar 

Zhu L, An L, Ran Di, Lizarraga R, Bondy C, Zhou X, Harper RW, Liao S-Y, Chen Y (2019) The club cell marker SCGB1A1 downstream of FOXA2 is reduced in asthma. Am J Respir Cell Mol Biol 60(6):695–704. https://doi.org/10.1165/rcmb.2018-0199OC

Article  CAS  Google Scholar 

Zuo W-L, Shenoy SA, Li S, O’Beirne SL, Strulovici-Barel Y, Leopold PL, Wang G, Staudt MR, Walters MS, Mason C, Kaner RJ, Mezey JG, Crystal RG (2018) Ontogeny and biology of human small airway epithelial club cells. Am J Respir Crit Care Med 198(11):1375–1388. https://doi.org/10.1164/rccm.201710-2107OC

Article  CAS  Google Scholar 

留言 (0)

沒有登入
gif