MeSH 搜索器

Dishevelled Proteins

A family of proteins that are key components of the WNT SIGNALING PATHWAY, where they function downstream of FRIZZLED RECEPTORS. They contain an N-terminal dishevelled-AXIN PROTEIN (DIX) domain, which mediates oligomerization; a central PDZ DOMAIN which binds to the frizzled receptor; and a C-terminal DEP domain which facilitates binding to the CELL MEMBRANE. Dishevelled proteins have important functions in CELL DIFFERENTIATION and establishing CELL POLARITY.
推出的年份: 2017(1994)
副标题
树号: D12.644.360.024.288, D12.776.157.057.028, D12.776.476.024.330
MeSH 单一 ID: D000072261
进入的组:
  • Dishevelled Protein
  • Dishevelled-3 Protein
  • Dishevelled 3 Protein
  • Dishevelled-1 Protein
  • Dishevelled 1 Protein
  • Dishevelled-2 Protein
  • Dishevelled 2 Protein

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