A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE.
推出的年份: 2017
副标题
树号: D08.811.277.785, D12.776.637.875
MeSH 单一 ID: D000071617
进入的组:
DJ-1, Protein Deglycase
DJ-1-PARK7 Protein
DJ 1 PARK7 Protein
DJ-1 Protein
DJ 1 Protein
Parkinson Protein 7
DJ1 Protein
PARK7 Protein
Parkinsonism Associated Deglycase
Deglycase, Parkinsonism Associated
早前的内容:
Intracellular Signaling Peptides and Proteins (1997-2016)
留言 (0)