Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
推出的年份: 1988
副标题
树号: G05.360.340.024.340.335, G12.500.299
MeSH 单一 ID: D005803
进入的组:
Immunoglobulin Genes
Gene, Immunoglobulin
Immunoglobulin Gene
Genes, Ig
Gene, Ig
Ig Gene
Ig Genes
早前的内容:
Genes, Structural (1972-1987)
Immunoglobulins (1972-1987)
specific immunoglobulin chain or region (1975-1987)
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