A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
推出的年份: 2017(1983)
副标题
树号: D12.776.157.464.500.875
MeSH 单一 ID: D000070796
进入的组:
Perilipin 3
TIP47 Protein
Protein, TIP47
47 kDa Mannose 6-Phosphate Receptor-Binding Protein
47 kDa Mannose 6 Phosphate Receptor Binding Protein
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