Endolysosomal organelles surrounded by multi-lamellar MEMBRANE LIPIDS. They are involved in diverse functions in storage and secretion of cellular LIPIDS. Lamellar bodies in the TYPE 2 PNEUMOCYTES produce and secrete PULMONARY SURFACTANT (e.g., DIPALMITOYL PHOSPHATIDYLCHOLINE). Lamellar bodies in the skin produce and secrete neutral lipids to provide hydrophobic barrier. Pathological accumulation of lamellar bodies are also known in lipid storage diseases (e.g.,LCAT DEFICIENCY; and HERMANSKY-PUDLAK SYNDROME).
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