A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
推出的年份: 2006(1987)
副标题
树号: D12.776.930.155.200
MeSH 单一 ID: D050657
进入的组:
Core Binding Factor alpha Proteins
Runx Proteins
Polyomavirus Enhancer A Binding Protein 2
Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
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