Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
推出的年份: 1992
副标题
树号: C19.787, C20.111.750
MeSH 单一 ID: D016884
进入的组:
Autoimmune Polyendocrinopathy
Polyendocrinopathy, Autoimmune
Polyglandular Type III Autoimmune Syndrome
Polyglandular Autoimmune Syndrome, Type 3
Autoimmune Syndrome Type III, Polyglandular
Autoimmune Polyglandular Syndrome Type III
Autoimmune Polyglandular Syndrome, Type 3
Polyglandular Type I Autoimmune Syndrome
APECED
APS Type 1
Autoimmune Polyendocrinopathy Syndrome Type 1
Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
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