MeSH 搜索器

Anistreplase

An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an activator that converts plasminogen to plasmin, thereby initiating fibrinolysis. Its half-life is about 90 minutes compared to 5 minutes for TPA; (TISSUE PLASMINOGEN ACTIVATOR); 16 minutes for UROKINASE-TYPE PLASMINOGEN ACTIVATOR and 23 minutes for STREPTOKINASE. If treatment is initiated within 3 hours of onset of symptoms for acute myocardial infarction, the drug preserves myocardial tissue and left ventricular function and increases coronary artery patency. Bleeding complications are similar to other thrombolytic agents.
推出的年份: 1991
副标题
树号: D08.811.277.656.300.760.635.075, D08.811.277.656.300.775.075, D08.811.277.656.959.350.635.075, D12.776.124.125.662.537.075
MeSH 单一 ID: D016255
进入的组:
  • APSAC
  • Anisoylated Plasminogen-Streptokinase Activator Complex
  • Iminase
  • BRL-26921
  • BRL 26921
  • BRL26921
  • Eminase
早前的内容:
  • Fibrinolytic Agents (1966-1990)
  • Plasminogen (1966-1990)
  • Streptokinase (1966-1990)
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