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Irinotecan
A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
推出的年份: 2019(1987)
副标题
administration and dosage
adverse effects
agonists
analogs and derivatives
analysis
antagonists and inhibitors
blood
cerebrospinal fluid
chemical synthesis
chemistry
classification
economics
history
immunology
isolation and purification
metabolism
pharmacokinetics
pharmacology
poisoning
radiation effects
standards
supply and distribution
therapeutic use
toxicity
urine
树号:
D03.132.151.425
MeSH 单一 ID:
D000077146
进入的组:
Irrinotecan
Camptothecin-11
Camptothecin 11
SN 38 11
SN-38-11
SN3811
SN 38
SN-38
NK012 Compound
CPT-11
CPT11
CPT 11
Camptosar
7-Ethyl-10-hydroxycamptothecin
7 Ethyl 10 hydroxycamptothecin
Irinotecan Hydrochloride
药理作用*:
Topoisomerase I Inhibitors
All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds [D03]
Alkaloids [D03.132]
Camptothecin [D03.132.151]
Irinotecan [D03.132.151.425]
Topotecan [D03.132.151.850]
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