MeSH 搜索器

Forkhead Box Protein L2

A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).
推出的年份: 2018
副标题
树号: D12.776.260.950.249.032, D12.776.930.977.249.032
MeSH 单一 ID: D000074842
进入的组:
  • Forkhead Box L2 Protein
  • FOXL2 Protein
早前的内容:
  • Forkhead Transcription Factors (2006-2017)

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