MeSH 搜索器

Valosin Containing Protein

A highly-conserved AAA ATPase that functions in the biogenesis of the transitional ENDOPLASMIC RETICULUM and fragmentation and reassembly of the GOLGI APPARATUS during MITOSIS. It also functions in a complex with UFD1L and NPLOC4 proteins to export misfolded ubiquitinated proteins from the endoplasmic reticulum and outer mitochondrial membrane to the cytoplasm for degradation by the PROTEASOME and also plays a role in AUTOPHAGY of ubiquitinated proteins. It occurs in neuronal INCLUSION BODIES from patients with AMYOTROPHIC LATERAL SCLEROSIS and LEWY BODIES from PARKINSON DISEASE patients.
推出的年份: 2018(1991)
副标题
树号: D08.811.277.040.013.500.750, D08.811.277.040.025.024.750, D12.776.157.025.750.750, D12.776.167.800
MeSH 单一 ID: D000074405
进入的组:
  • Cell Cycle Protein CDC48
  • Valosine-Containing Protein
  • Valosine Containing Protein
  • p97 Valosin-Containing Protein
  • Valosin-Containing Protein, p97
  • p97 Valosin Containing Protein
  • Valosin-Containing Protein
  • CDC48 Protein
  • Cell Cycle Protein CDC48p

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