A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
推出的年份: 1988
副标题
树号: D02.455.426.559.847.638.400, D04.615.638.400
MeSH 单一 ID: D008148
进入的组:
Mevinolin
Monacolin K
6-Methylcompactin
6 Methylcompactin
MK-803
MK 803
MK803
Mevacor
Lovastatin, (1 alpha(S*))-Isomer
Lovastatin, 1 alpha-Isomer
1 alpha-Isomer Lovastatin
Lovastatin, 1 alpha Isomer
alpha-Isomer Lovastatin, 1
早前的内容:
Anticholesteremic Agents (1966-1987)
Hydroxymethylglutaryl CoA Reductases/antagonists & inhibitors (1977-1987)
留言 (0)