AbbreviationsBAFF
B-cell activating factor of the tumor necrosis factor superfamily
BEC
blood endothelial cells
BMP,
bone morphogenetic protein
cTEC,
cortical thymic epithelial cells
CTL,
Cytotoxic T lymphocytes
ECM,
extra cellular matrix
ETPs,
early T-lineage progenitors
FDC,
follicular dendritic cells
FRC,
fibroblastic reticular cells
GDF11,
growth differentiation factor 11
HEV,
high endothelial venule
HSV-1,
herpes simplex virus 1
IFRC,
inter follicular reticular cells
KGF
keratinocyte growth factor
LCMV,
lymphocytic choriomeningitis virus
LEC,
lymphatic endothelial cells
LTβR,
lymphotoxin beta receptor
LTi
lymphoid tissue inducer
LTo
lymphoid tissue organizer
LYVE-1
lymphatic vessel endothelial hyaluronan receptor 1
MedRC,
medullary reticular cells
MRC,
marginal reticular cells
mTEC,
medullary thymic epithelial cells
PDGFR,
platelet-derived growth factor receptor
pLN
peripheral lymph nodes
PNAd
peripheral node addessin
PROX1,
prospero homeobox protein 1
RANKL
receptor activator of nuclear factor kappa-B ligand
RTE
recent thymic emigrants
SASP
senescence-associated secretory phenotype
SLO
secondary lymphoid organs
TBRC,
T-B border reticular cells
Tfh cells
follicular helper T cells
TGF-β
Transforming growth factor beta
TRC,
T-cell zone reticular cells
Keywords
Immune aging
Lymphoid stromal cells
Lymph node involution
Secondary lymphoid organs
T cell homeostasis
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