1 Department of Microbiology, University of Georgia, Athens USA.

Keywords: cobamide nucleobases, 5,6-dimethylbenzimidazole, CoB12 biosynthesis, benzimidazole antimicrobials, flavoenzyme inhibitors.

Abbreviations:

5-FOA - 5-fluoroorotate,

5-Me-Bza - 5-methylbenzimidazole,

Cbas – cobamides,

DMB – 5,6-dimethylbenzimidazole,

EtBr – Ethidium bromide,

Fre – flavin reductase,

PMF – proton motive force,

Sdh – succinate dehydrogenase,

TSS – transcription start site.
Received originally: 18/05/2023 Received in revised form: 27/07/2023
Accepted: 07/08/2023 Published: 17/08/2023

Correspondence:
Jorge C. Escalante-Semerena, 212C Biological Sciences Building, 120 Cedar Street, Athens, GA 30602 USA; jcescala@uga.edu

Conflict of interest statement: The authors declare no conflict of interest with this work.
Please cite this article as: Lahiru Malalasekara and Jorge C. Escalante-Semerena (2023). The coenzyme B12 precursor 5,6-dimethylbenzimidazole is a flavin antagonist in Salmonella. Microbial Cell 10(9): 178-194. doi: 10.15698/mic2023.09.803