Methyltransferase-independent function of enhancer of zeste homologue 2 maintains tumorigenicity induced by human oncogenic papillomavirus and polyomavirus

Keywords

Merkel cell polyomavirus

Merkel cell carcinoma

Human papillomavirus

Oropharyngeal squamous cell carcinoma

Enhancer of zeste homolog 2

EZH2 methyltransferase-independent function

AbbreviationsMCV

Merkel Cell Polyomavirus

OSCC

Oropharyngeal Squamous Cell Carcinoma

pRb

Retinoblastoma tumor suppressor protein

EZH2

Enhancer of zeste homolog 2

PRC2

Polycomb Repressive Complex 2

H3K27me3

Histone H3 trimethylated at lysine 27

PROTAC

proteolysis-targeting chimera

Data availability

Data will be made available on request.

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