Serum E-selectin and endothelial cell-specific Molecule-1 levels among people living with HIV on long term ART in Uganda: a pilot cross-sectional study

Cheza A, Tlou B, Zhou DTJPo. Incidence of non-communicable diseases (NCDs) in HIV patients on ART in a developing country: Case of Zimbabwe’s Chitungwiza Central Hospital—A retrospective cohort study (2010–2019). 2021;16(5):e0252180.

Kansiime S, Mwesigire D, Mugerwa HJPo. Prevalence of non-communicable diseases among HIV positive patients on antiretroviral therapy at joint clinical research centre. Lubowa Uganda. 2019;14(8):e0221022.

CAS  Google Scholar 

Shah ASV, Stelzle D, Lee KK, Beck EJ, Alam S, Clifford S, et al. Global Burd Atherosclerotic Cardiovasc Disease People Living HIV. 2018;138(11):1100–12.

Google Scholar 

Smit M, Brinkman K, Geerlings S, Smit C, Thyagarajan K, Sighem Av, et al. Future challenges for clinical care of an ageing population infected with HIV: a modelling study. Lancet Infect Dis. 2015;15(7):810–8.

Article  PubMed  PubMed Central  Google Scholar 

Anand AR, Rachel G, Parthasarathy D. HIV Proteins and endothelial dysfunction: implications in Cardiovascular Disease. Front Cardiovasc Med. 2018;5:185.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Incalza MA, D’Oria R, Natalicchio A, Perrini S, Laviola L, Giorgino F. Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. Vascul Pharmacol. 2018;100:1–19.

Article  CAS  PubMed  Google Scholar 

Kline ER, Sutliff RLJJoIM. The roles of HIV-1 proteins and antiretroviral drug therapy in HIV-1-associated endothelial dysfunction. 2008;56(5):752–69.

Messner B, Bernhard DJA. thrombosis, biology v. Smoking and cardiovascular disease: mechanisms of endothelial dysfunction and early atherogenesis. 2014;34(3):509–15.

Goncharov NV, Popova PI, Avdonin PP, Kudryavtsev IV, Serebryakova MK, Korf EA, et al. Markers of endothelial cells in normal and pathological conditions. Biochemistry (Moscow). Supplement Ser A: Membrane Cell Biology. 2020;14(3):167–83.

CAS  Google Scholar 

Mosepele M, Mohammed T, Mupfumi L, Moyo S, Bennett K, Lockman S, et al. HIV disease is associated with increased biomarkers of endothelial dysfunction despite viral suppression on long-term antiretroviral therapy in Botswana. Cardiovasc J Afr. 2018;29(3):155–61.

Article  PubMed  PubMed Central  Google Scholar 

Fourie C, Schutte A, Smith W, Kruger A, Van Rooyen JJA. Endothelial activation and cardiometabolic profiles of treated and never-treated HIV infected Africans. 2015;240(1):154–60.

Fourie C, Van Rooyen J, Pieters M, Conradie K, Hoekstra T, Schutte AJCjoA. Is HIV-1 infection associated with endothelial dysfunction in a population of African ancestry in South Africa?: cardiovascular topics. 2011;22(3):134–40.

Hoffman M, Ipp H, Phatlhane DV, Erasmus RT, Zemlin AE. E-Selectin and markers of HIV disease severity, inflammation and coagulation in HIV-infected treatment-naïve individuals. Afr Health Sci. 2018;18(4):1066–75.

Article  PubMed  PubMed Central  Google Scholar 

Rönsholt FF, Ullum H, Katzenstein TL, Gerstoft J, Ostrowski, SRJPo. Persistent inflammation and endothelial activation in HIV-1 infected patients after 12 years of antiretroviral therapy. 2013;8(6):e65182.

Mezoh G, Crowther NJ. Deciphering endothelial dysfunction in the HIV-Infected Population. In: Guest PC, editor. Reviews on Biomarker Studies of metabolic and metabolism-related Disorders. Cham: Springer International Publishing; 2019. pp. 193–215.

Chapter  Google Scholar 

Imhof BA, Dunon D. Leukocyte Migration and Adhesion. In: Dixon FJ, editor. Advances in Immunology. Volume 58. Academic Press; 1995. pp. 345–416.

Chen J, Jiang L, Yu X-H, He P, Ouyang X, Hu M et al. Endocan: a key player of cardiovascular disease. 2021:2079.

de Almeida-Pititto B, Ribeiro-Filho FF, Bittencourt MS, Lotufo PA, Bensenor I, Ferreira SRG. Usefulness of circulating E-selectin to early detection of the atherosclerotic process in the brazilian longitudinal study of Adult Health (ELSA-Brasil). Diabetol Metab Syndr. 2016;8(1):19.

Article  PubMed  PubMed Central  Google Scholar 

Zhao T, Kecheng Y, Zhao X, Hu X, Zhu J, Wang Y et al. The higher serum endocan levels may be a risk factor for the onset of cardiovascular disease: A meta-analysis. 2018;97(49):e13407.

Kristoffersen U, Kofoed K, Kronborg G, Giger A, Kjaer A, Lebech A. Reduction in circulating markers of endothelial dysfunction in HIV-infected patients during antiretroviral therapy. 2009;10(2):79–87.

Kristoffersen U, Kofoed K, Kronborg G, Giger A, Kjaer A, Lebech AJHm. Reduction in circulating markers of endothelial dysfunction in HIV-infected patients during antiretroviral therapy. 2009;10(2):79–87.

Castelnuovo B, Mubiru F, Kiragga AN, Musomba R, Mbabazi O, Gonza P et al. Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda. 2018;8(2):e015490.

Ross SM. Chapter 6 - distributions of sampling statistics. In: Ross SM, editor. Introduction to Probability and Statistics for engineers and scientists. Sixth Edition): Academic Press; 2021. pp. 221–44.

Chapter  Google Scholar 

Timmerman I, Daniel AE, Kroon J, van Buul JDJIRoC, Biology M. Leukocytes crossing the endothelium: a matter of communication. 2016;322:281–329.

Poon PY-K, Ng JK-C, Fung WW-S, Chow K-M, Kwan BC-H, Li PK-T et al. Relationship between plasma endocan level and clinical outcome of chinese peritoneal dialysis patients. 2019;44(5):1259–70.

He X-W, Ke S-F, Bao Y-Y, Hong W-J, Shen Y-G, Li C et al. Serum levels of endocan and endoglin are associated with large-artery atherosclerotic stroke. 2018;478:157–61.

WHO. A healthy lifestyle - WHO recommendations Geneva: World Health Organisation.; 2010 [Available from: https://www.who.int/europe/news-room/fact-sheets/item/a-healthy-lifestyle---who-recommendations.

Cota-Gomez A, Flores NC, Cruz C, Casullo A, Aw TY, Ichikawa H, et al. The Human Immunodeficiency Virus-1 Tat Protein Activates Human Umbilical Vein Endothelial Cell E-selectin Expression via an NF-κB-dependent Mechanism *. Journal of Biological Chemistry. 2002;277(17):14390-9.

Marincowitz C, Genis A, Goswami N, De Boever P, Nawrot TS, Strijdom H. Vascular endothelial dysfunction in the wake of HIV and ART. 2019;286(7):1256–70.

Jiang B, Hebert VY, Zavecz JH, Dugas TRJJJoAIDS. Antiretrovirals induce direct endothelial dysfunction in vivo. 2006;42(4):391–5.

Jiang B, Hebert VY, Li Y, Mathis JM, Alexander JS, Dugas TRJT, et al. HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production. but not apoptosis. 2007;224(1):60–71.

CAS  PubMed  Google Scholar 

Fisher SD, Miller TL, Lipshultz SEJA. Impact of HIV and highly active antiretroviral therapy on leukocyte adhesion molecules, arterial inflammation, dyslipidemia, and atherosclerosis. 2006;185(1):1–11.

Ziaee M, Mashayekhi S, Ghaffari S, Mahmoudi J, Sarbakhsh P, Garjani AJA. Predictive value of endocan based on TIMI risk score on major adverse cardiovascular events after acute coronary syndrome. 2019;70(10):952–9.

Icli A, Cure E, Cure MC, Uslu AU, Balta S, Mikhailidis DP et al. Endocan levels and subclinical atherosclerosis in patients with systemic lupus erythematosus. 2016;67(8):749–55.

Seo K, Kitazawa T, Yoshino Y, Koga I, Ota YJPo. Characteristics of serum endocan levels in infection. 2015;10(4):e0123358.

Pauly D, Hamed S, Behnes M, Lepiorz D, Lang S, Akin I et al. Endothelial cell-specific molecule–1/endocan: Diagnostic and prognostic value in patients suffering from severe sepsis and septic shock. 2016;31(1):68–75.

Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, et al. The association of CD4 + T-cell counts and cardiovascular risk in treated HIV disease. AIDS. 2012;26(9):1115–20.

Article  PubMed  Google Scholar 

Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, et al. Elevated levels of asymmetric dimethylarginine are associated with lower CD4 + count and higher viral load in HIV-infected individuals. Atherosclerosis. 2013;229(1):246–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

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