Trough Concentration Response in Infliximab and Adalimumab Treated Children With Inflammatory Bowel Disease Following Treatment Adjustment: A Pharmacokinetic Model

From the *Department of Pediatrics “A”, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel

†The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

‡The Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Hospital, Petach-Tikva, Israel

§The Juliet Keidan Institute of Pediatric Gastroenterology, Hepatology and Nutrition, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel.

Received December 25, 2022; accepted January 26, 2023.

The authors report no conflicts of interest.

Address correspondence and reprint requests to Rachel Levy, MD, Department of Pediatrics “A”, Schneider Children’s Medical Center of Israel, 14 Kaplan St., Petach-Tikva, 4920235, Israel (e-mail: [email protected]).

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