Although tonotopic place-coding in the cochlea has been extensively studied, our understanding of how the human cochlea responds in vivo to acoustic stimuli remains limited. We recorded acoustically-evoked intracochlear responses from 50 human subjects using a cochlear implant electrode and constructed an electrophysiology-based map using postoperative imaging to locate each electrode contact. The basal shifted frequency-place map resulting from higher stimulation more closely aligns with everyday speech levels.

C.A.B. serves as a consultant for Advanced Bionics, Cochlear Ltd., Envoy, and IotaMotion and has equity interest in Advanced Cochlear Diagnostics. J.A.H. serves as a consultant for Cochlear Ltd. For the remaining authors, none were declared.

AW was supported by NIH/NIDCD institutional training grant T32DC000022. CAB is supported by Department of Defense grant W81XWH19C0054 and NIH/NIDCD grant DC020936-01.

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Institutional Review Board of Washington University in St. Louis gave ethical approval of this work.

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