Flegal KM, et al. Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002;288(14):1723–7.

Article  PubMed  Google Scholar 

Hales CM, et al. Prevalence of obesity and severe obesity among adults: United States, 2017–2018. NCHS Data Brief. 2020;360:1–8.

Google Scholar 

Driscoll AK, Gregory ECW. Increases in prepregnancy obesity: United States, 2016–2019. NCHS Data Brief. 2020;392:1–8.

Google Scholar 

Catalano PM, Shankar K. Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child. BMJ. 2017;356:j1.

Article  PubMed  PubMed Central  Google Scholar 

Ellulu MS, et al. Obesity and inflammation: the linking mechanism and the complications. Arch Med Sci. 2017;13(4):851–63.

Article  CAS  PubMed  Google Scholar 

Brombach C, Tong W, Giussani DA. Maternal obesity: new placental paradigms unfolded. Trends Mol Med. 2022;28(10):823–35.

Article  CAS  PubMed  Google Scholar 

Ramsay JE, et al. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab. 2002;87(9):4231–7.

Article  CAS  PubMed  Google Scholar 

Agarwal P, et al. Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring. Crit Rev Clin Lab Sci. 2018;55(2):71–101.

Article  CAS  PubMed  Google Scholar 

Poston L, et al. Obesity in pregnancy: implications for the mother and lifelong health of the child. A consensus statement. Pediatr Res. 2011;69(2):175–80.

Article  PubMed  Google Scholar 

Lane-Cordova AD, et al. Long-term cardiovascular risks associated with adverse pregnancy outcomes: JACC review topic of the week. J Am Coll Cardiol. 2019;73(16):2106–16.

Article  PubMed  Google Scholar 

Khan SS, et al. Association of body mass index with lifetime risk of cardiovascular disease and compression of morbidity. JAMA Cardiol. 2018;3(4):280–7.

Article  PubMed  PubMed Central  Google Scholar 

• Vats H, et al. Impact of maternal pre-pregnancy body mass index on maternal, fetal and neonatal adverse outcomes in the worldwide populations: a systematic review and meta-analysis. Obes Res Clin Pract. 2021;15(6):536–45. This systematic review and meta-analysis of 86 studies found that elevated prepregnancy maternal BMI was associated with higher odds of multiple maternal and fetal outcomes including gestational diabetes, gestational hypertension, and preeclampsia, among others.

Davis MB, et al. Team-based care of women with cardiovascular disease from pre-conception through pregnancy and postpartum: JACC focus seminar 1/5. J Am Coll Cardiol. 2021;77(14):1763–77.

Article  PubMed  PubMed Central  Google Scholar 

•• Parikh NI, et al. Adverse pregnancy outcomes and cardiovascular disease risk: unique opportunities for cardiovascular disease prevention in women: a scientific statement from the American Heart Association. Circulation. 2021;143(18):e902-16. This AHA statement summarized current evidence relating adverse pregnancy outcomes and the risk of developing cardiovascular disease.

• Minhas AS, et al. The association of adverse pregnancy outcomes and cardiovascular disease: current knowledge and future directions. Curr Treat Options Cardiovasc Med. 2020;22(12). This review discussed the nature of the association between adverse pregnancy outcomes and risk for future maternal cardiovascular disease and identified gaps in current knowledge regarding underlying pathophysiologic mechanisms.

Grandi SM, et al. Cardiovascular disease-related morbidity and mortality in women with a history of pregnancy complications. Circulation. 2019;139(8):1069–79.

Article  PubMed  Google Scholar 

Crane JM, et al. Maternal and perinatal outcomes of extreme obesity in pregnancy. J Obstet Gynaecol Can. 2013;35(7):606–11.

Article  PubMed  Google Scholar 

• D'Souza R, et al. Maternal body mass index and pregnancy outcomes: a systematic review and metaanalysis. Am J Obstet Gynecol MFM. 2019;1(4):100041. This systematic review and meta-analysis of 13 studies demonstrated a linear association between maternal prepregnancy BMI and many adverse pregnancy outcomes.

Yang Z, et al. Contribution of maternal overweight and obesity to the occurrence of adverse pregnancy outcomes. Aust N Z J Obstet Gynaecol. 2019;59(3):367–74.

Article  PubMed  Google Scholar 

Bicocca MJ, et al. Maternal obesity and the risk of early-onset and late-onset hypertensive disorders of pregnancy. Obstet Gynecol. 2020;136(1):118–27.

Article  CAS  PubMed  Google Scholar 

Ying W, Catov JM, Ouyang P. Hypertensive disorders of pregnancy and future maternal cardiovascular risk. J Am Heart Assoc. 2018;7(17):e009382.

Article  PubMed  PubMed Central  Google Scholar 

Brown MC, et al. Cardiovascular disease risk in women with pre-eclampsia: systematic review and meta-analysis. Eur J Epidemiol. 2013;28(1):1–19.

Article  PubMed  Google Scholar 

Wu P, et al. Preeclampsia and future cardiovascular health: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2017;10(2):e003497.

Article  PubMed  Google Scholar 

McDonald SD, et al. Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses. Am Heart J. 2008;156(5):918–30.

Article  PubMed  Google Scholar 

Wang YX, et al. Hypertensive disorders of pregnancy and subsequent risk of premature mortality. J Am Coll Cardiol. 2021;77(10):1302–12.

Article  PubMed  PubMed Central  Google Scholar 

Timpka S, et al. Lifestyle in progression from hypertensive disorders of pregnancy to chronic hypertension in Nurses’ Health Study II: observational cohort study. BMJ. 2017;358:j3024.

Article  PubMed  PubMed Central  Google Scholar 

Lo CCW, et al. Future Cardiovascular disease risk for women with gestational hypertension: a systematic review and meta-analysis. J Am Heart Assoc. 2020;9(13):e013991.

Article  PubMed  PubMed Central  Google Scholar 

Chu SY, et al. Maternal obesity and risk of gestational diabetes mellitus. Diabetes Care. 2007;30(8):2070–6.

Article  PubMed  Google Scholar 

Helle E, Priest JR. Maternal obesity and diabetes mellitus as risk factors for congenital heart disease in the offspring. J Am Heart Assoc. 2020;9(8):e011541.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ye W, et al. Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis. BMJ. 2022;377:e067946.

Article  PubMed  PubMed Central  Google Scholar 

Kc K, Shakya S, Zhang H. Gestational diabetes mellitus and macrosomia: a literature review. Ann Nutr Metab. 2015;66(Suppl 2):14–20.

Article  CAS  PubMed  Google Scholar 

Vounzoulaki E, et al. Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis. BMJ. 2020;369:m1361.

Article  PubMed  PubMed Central  Google Scholar 

Rayanagoudar G, et al. Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women. Diabetologia. 2016;59(7):1403–11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

McDonald SD, et al. Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and meta-analyses. BMJ. 2010;341:c3428.

Article  PubMed  PubMed Central  Google Scholar 

Cnattingius S, et al. Maternal obesity and risk of preterm delivery. JAMA. 2013;309(22):2362–70.

Article  CAS  PubMed  Google Scholar 

Liu B, et al. Association between maternal pre-pregnancy obesity and preterm birth according to maternal age and race or ethnicity: a population-based study. Lancet Diabetes Endocrinol. 2019;7(9):707–14.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu P, et al. Preterm delivery and future risk of maternal cardiovascular disease: a systematic review and meta-analysis. J Am Heart Assoc. 2018;7(2):e007809.

Article  PubMed  PubMed Central  Google Scholar 

Crump C, et al. Pre-term delivery and risk of ischemic heart disease in women. J Am Coll Cardiol. 2020;76(1):57–67.

Article  PubMed  PubMed Central  Google Scholar 

Rich-Edwards JW, et al. Duration of pregnancy, even at term, predicts long-term risk of coronary heart disease and stroke mortality in women: a population-based study. Am J Obstet Gynecol. 2015;213(4):518e1–8.

Article  PubMed Central  Google Scholar 

Elkayam U, et al. High-risk cardiac disease in pregnancy: part I. J Am Coll Cardiol. 2016;68(4):396–410.

Article  PubMed  Google Scholar 

• Pfaller B, et al. Impact of obesity on outcomes of pregnancy in women with heart disease. J Am Coll Cardiol. 2021;77(10):1317–26.This study found that obesity increased the risk of maternal complications in pregnant individuals with cardiovascular disease.

Kankowski L, et al. The impact of maternal obesity on offspring cardiovascular health: a systematic literature review. Front Endocrinol (Lausanne). 2022;13:868441.

Article  PubMed  Google Scholar 

Liu P, et al. Association between perinatal outcomes and maternal pre-pregnancy body mass index. Obes Rev. 2016;17(11):1091–102.

Article  CAS  PubMed  Google Scholar 

Aune D, et al. Maternal body mass index and the risk of fetal death, stillbirth, and infant death: a systematic review and meta-analysis. JAMA. 2014;311(15):1536–46.

Article  CAS  PubMed