Novel Insights from Clinical Practice

Gavazzoni Dias M.F.R.a· Lofeu Cury A.a· Vilar E.A.G.b· Peixoto P.G.c,d· Ekelem C.

Author affiliations

aDepartment of Dermatology, Hospital Universitário Antônio Pedro, Niterói, Brazil
bDepartment of Pathology, Hospital Universitário Antônio Pedro, Niterói, Brazil
cClínica Patricia Guimarães – Medicina e Tricologia, Santa Efigênia, Belo Horizonte, Brazil
dDepartment of Dermatology, University of Utah, Salt Lake City, UT, USA

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Article / Publication Details

Received: November 30, 2022
Accepted: February 13, 2023
Published online: March 30, 2023

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 1

ISSN: 2296-9195 (Print)
eISSN: 2296-9160 (Online)

For additional information: https://www.karger.com/SAD

Abstract

Introduction: Frontal Fibrosing Alopecia (FFA) and Fibrosing Alopecia in a Pattern Distribution (FAPD) are two distinct entities of cicatricial pattern hair loss that share histological features of perifollicular lichenoid inflammation associated with concentric fibrosis. Although the pathophysiology of FFA and FAPD are still unknown, recently published reports of familial cases indicate a possible genetic correlation. Case Presentation: We report 6 cases of familial alopecia composed of mothers and daughters: five with FFA and one with FAPD. We describe clinical, trichoscopy and histological correlation in cases of familial alopecia. Conclusions: These cases of mother and daughter disease association suggest a potential benefit of and role for performing systematic scalp examinations of all first-degree relatives of patients with pattern cicatricial alopecia.

© 2023 S. Karger AG, Basel

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Received: November 30, 2022
Accepted: February 13, 2023
Published online: March 30, 2023

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 1

ISSN: 2296-9195 (Print)
eISSN: 2296-9160 (Online)

For additional information: https://www.karger.com/SAD

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