Epigenetics
Histone demethylase
LSD1 inhibitors
Structure-activity relationships
TAK-418
AbbreviationsAIDSacquired immune deficiency syndrome
AMLacute myeloid leukemia
APLAcute promyelocytic leukemia
CNScentral nervous system
hERGhuman ether-a-go-go-related gene
FADflavin adenine dinucleotide
GFI1Growth factor independent 1 transcriptional repressor
GFI1BGrowth factor independent 1B transcriptional repressor
IGFBP3insulin-like growth factor-binding protein 3
LSD2Lysine-specific demethylase 2
MAPKmitogen-activated protein kinase
MLLmixed-lineage leukemia
mTORmammalian target of rapamycin
MYCNv-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NMDAN-methyl-d-aspartic acid
2-PCPA2-phenylcycloproylamine
PI3Kphosphatidylinositol 3 kinase
TNF-αTumor necrosis factor-α
T-ALLT-cell acute lymphoblastic leukemia
Data availabilityThe data that has been used is confidential.
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