Cystic Renal Masses

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Bosniak classification of cystic renal masses, version 2019: an update proposal and needs assessment.

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Update on MRI of cystic renal masses including Bosniak Version 2019.

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Malignancy rates and diagnostic performance of the Bosniak classification for the diagnosis of cystic renal lesions in computed tomography: a systematic review and meta-analysis.

Eur Radiol. 27: 2239-2247Richard P.O. Violette P.D. Jewett M.A.S. et al.

CUA guideline on the management of cystic renal lesions.

Can Urol Assoc J. 11: 66Schoots I.G. Zaccai K. Hunink M.G. et al.

Bosniak Classification for Complex Renal Cysts reevaluated: a systematic review.

J Urol. 198: 12-21Smith A.D. Remer E.M. Cox K.L. et al.

Bosniak category IIF and III cystic renal lesions: outcomes and associations.

Radiology. 262: 152-160

The current radiological approach to renal cysts.

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From the RSNA Refresher Courses: a practical approach to the cystic renal mass.

Radiographics. 24: S101-S115Heilbrun M.E. Remer E.M. Casalino D.D. et al.

ACR Appropriateness Criteria Indeterminate Renal Mass.

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The natural history of observed enhancing renal masses: meta-analysis and review of the world literature.

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Dual-energy CT with single- and dual-source scanners: current applications in evaluating the genitourinary tract.

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Renal cyst pseudoenhancement: beam-hardening effects on CT numbers.

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Pseudoenhancement of renal cysts: influence of lesion size, lesion location, slice thickness, and number of MDCT detectors.

AJR Am J Roentgenol. 198: 133-137Siddaiah M. Krishna S. McInnes M.D.F. et al.

Is ultrasound useful for further evaluation of homogeneously hyperattenuating renal lesions detected on CT?.

AJR Am J Roentgenol. 209: 604-610Park B.K. Kim B. Kim S.H. et al.

Assessment of cystic renal masses based on Bosniak classification: comparison of CT and contrast-enhanced US.

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Ultrasound-based “CEUS-Bosniak” classification for cystic renal lesions: an 8-year clinical experience.

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Evaluation of cystic renal masses: comparison of CT and MR imaging by using the Bosniak classification system.

Radiology. 231: 365-371Ferreira A.M. Reis R.B. Kajiwara P.P. et al.

MRI evaluation of complex renal cysts using the Bosniak classification: a comparison to CT.

Abdom Radiol. 41: 2011-2019Ramamurthy N.K. Moosavi B. McInnes M.D.F. et al.

Multiparametric MRI of solid renal masses: pearls and pitfalls.

Clin Radiol. 70: 304-316Wang H. Cheng L. Zhang X. et al.

Renal cell carcinoma: diffusion-weighted MR imaging for subtype differentiation at 3.0 T.

Radiology. 257: 135-143Rosenkrantz A.B. Wehrli N.E. Mussi T.C. et al.

Complex cystic renal masses: comparison of cyst complexity and Bosniak classification between 1.5T and 3T MRI.

Eur J Radiol. 83: 503-508Volpe A. Finelli A. Gill I.S. et al.

Rationale for percutaneous biopsy and histologic characterisation of renal tumours.

Eur Urol. 62: 491-504Herrera-Caceres J.O. Finelli A. Jewett M.A.S.

Renal tumor biopsy: indicators, technique, safety, accuracy results, and impact on treatment decision management.

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Renal tumor biopsy for small renal masses: a single-center 13-year experience.

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European Association of Urology Guidelines on Renal Cell Carcinoma: the 2019 update.

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Contemporary results and clinical utility of renal mass biopsies in the setting of ablative therapy: a single center experience.

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Contemporary results of percutaneous biopsy of 100 small renal masses: a single center experience.

J Urol. 180: 2333-2337Marconi L. Dabestani S. Lam T.B. et al.

Systematic review and meta-analysis of diagnostic accuracy of percutaneous renal tumour biopsy.

Eur Urol. 69: 660-673Luomala L. Rautiola J. Järvinen P. et al.

Active surveillance versus initial surgery in the long-term management of Bosniak IIF–IV cystic renal masses.

Sci Rep. 12Sefik E. Bozkurt I.H. Adibelli Z.H. et al.

The histopathologic correlation of Bosniak 3 cyst subclassification.

Urology. 129: 126-131Westerman M.E. Cheville J.C. Lohse C.M. et al.

Long-term outcomes of patients with low grade cystic renal epithelial neoplasms.

Urology. 133: 145-150Williamson S.R. Eble J.N. Cheng L. et al.

Clear cell papillary renal cell carcinoma: differential diagnosis and extended immunohistochemical profile.

Mod Pathol. 26: 697-708Zhou H. Zheng S. Truong L.D. et al.

Clear cell papillary renal cell carcinoma is the fourth most common histologic type of renal cell carcinoma in 290 consecutive nephrectomies for renal cell carcinoma.

Hum Pathol. 45: 59-64

Differential diagnoses in surgical pathology: genitourinary system.

Lippincott Williams & Wilkins, Philadelphia, PAMurad T. Komaiko W. Oyasu R. et al.

Multilocular cystic renal cell carcinoma.

Am J Clin Pathol. 95: 633-637Montironi R. Mazzucchelli R. Lopez-Beltran A. et al.

Cystic nephroma and mixed epithelial and stromal tumour of the kidney: opposite ends of the spectrum of the same entity?.

Eur Urol. 54: 1237-1246Sahni V.A. Mortele K.J. Glickman J. et al.

Mixed epithelial and stromal tumour of the kidney: imaging features.

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Mixed epithelial and stromal tumor of the kidney.

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Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma.

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Tubulocystic renal cell carcinoma: a review of literature focused on radiological findings for differential diagnosis.

Abdom Radiol. 43: 1540-1545Cornelis F. Hélénon O. Correas J.M. et al.

Tubulocystic renal cell carcinoma: a new radiological entity.

Eur Radiol. 26: 1108-1115Kuroda N. Ohe C. Mikami S. et al.

Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects.

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CT features of acquired cystic kidney disease-associated renal cell carcinoma.

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Natural history of complex renal cysts: clinical evidence supporting active surveillance.

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Comparable survival outcome between acquired cystic disease associated renal cell carcinoma and clear cell carcinoma in patients with end-stage renal disease: a multi-institutional central pathology study.

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Multilocular cystic renal cell carcinoma.

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The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.

Am J Surg Pathol. 37: 1469-1489Suzigan S. López-Beltrán A. Montironi R. et al.

Multilocular cystic renal cell carcinoma.

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VHL gene mutations and their effects on hypoxia inducible factor HIF: identification of potential driver and passenger mutations.

Cancer Res. 71: 5500-5511Nassir A. Jollimore J. Gupta R. et al.

Multilocular cystic renal cell carcinoma: a series of 12 cases and review of the literature.

Urology. 60: 421-427

Multilocular cystic renal cell carcinoma: a rare entity with review of literature.

J Lab Physicians. 6: 050-052Bhatt J.R. Jewett M.A.S. Richard P.O. et al.

Multilocular cystic renal cell carcinoma: pathological T staging makes no difference to favorable outcomes and should be reclassified.

J Urol. 196: 1350-1355Webster W.S. Thompson R.H. Cheville J.C. et al.

Surgical resection provides excellent outcomes for patients with cystic clear cell renal cell carcinoma.

Urology. 70: 900-904Boissier R. Ouzaid I. Nouhud F.X. et al.

Long-term oncological outcomes of cystic renal cell carcinoma according to the Bosniak classification.

Int Urol Nephrol. 51: 951-958Kashan M. Ghanaat M. Hötker A.M. et al.

Cystic renal cell carcinoma: a report on outcomes of surgery and active surveillance in patients retrospectively identified on pretreatment imaging.

J Urol. 200: 275-282Tretiakova M. Mehta V. Kocherginsky M. et al.

Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum.

Virchows Arch. 473: 85-93Diolombi M.L. Cheng L. Argani P. et al.

Do clear cell papillary renal cell carcinomas have malignant potential?.

Am J Surg Pathol. 39: 1621-1634Couvidat C. Eiss D. Verkarre V. et al.

Renal papillary carcinoma: CT and MRI features.

Diagn Interv Imaging. 95: 1055-1063Egbert N.D. Caoili E.M. Cohan R.H. et al.

Differentiation of papillary renal cell carcinoma subtypes on CT and MRI.

AJR Am J Roentgenol. 201: 347-355Procházková K. Mírka H. Trávníček I. et al.

Cystic appearance on imaging methods (Bosniak III-IV) in histologically confirmed papillary renal cell carcinoma is mainly characteristic of papillary renal cell carcinoma type 1 and might predict a relatively indolent behavior of papillary renal cell carcinoma.

Urol Int. 101: 409-416Lane B.R. Campbell S.C. Remer E.M. et al.

Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney: clinical, radiographic, and pathologic characteristics.

Urology. 71: 1142-1148Chu L.C. Hruban R.H. Horton K.M. et al.

Mixed epithelial and stromal tumor of the kidney: radiologic-pathologic correlation.

Radiographics. 30: 1541-1551Caliò A. Eble J.N. Grignon D.J. et al.

Cystic nephroma in adults.

Am J Surg Pathol. 40: 1591-1600Tse J.R. Shen J. Shen L. et al.

Bosniak Classification of Cystic Renal Masses Version 2019: comparison of categorization using CT and MRI.

AJR Am J Roentgenol. 216: 412-420Rasmussen R.G. Xi Y. Sibley R.C. et al.

Association of clear cell likelihood score on MRI and growth kinetics of small solid renal masses on active surveillance.

AJR Am J Roentgenol. 218: 101-110Finelli A. Cheung D.C. Al-Matar A. et al.

Small renal mass surveillance: histology-specific growth rates in a biopsy-characterized cohort.

Eur Urol. 78: 460-467Mason R.J. Abdolell M. Trottier G. et al.

Growth kinetics of renal masses: analysis of a prospective cohort of patients undergoing active surveillance.

Eur Urol. 59: 863-867Crispen P.L. Viterbo R. Boorjian S.A. et al.

Natural history, growth kinetics, and outcomes of untreated clinically localized renal tumors under active surveillance.

Cancer. 115: 2844-2852Bhindi B. Thompson R.H. Lohse C.M. et al.

The probability of aggressive versus indolent histology based on renal tumor size: implications for surveillance and treatment.

Eur Urol. 74: 489-497Goenka A.H. Remer E.M. Smith A.D. et al.

Development of a clinical prediction model for assessment of malignancy risk in Bosniak III renal lesions.

Urology. 82: 630-635Mousessian P.N. Yamauchi F.I. Mussi T.C. et al.

Malignancy rate, histologic grade, and progression of Bosniak category III and IV complex renal cystic lesions.

AJR Am J Roentgenol. 209: 1285-1290Smith A.D. Allen B.C. Sanyal R. et al.

Outcomes and complications related to the management of Bosniak cystic renal lesions.

AJR Am J Roentgenol. 204: W550-W556Smith A.D. Carson J.D. Sirous R. et al.

Active surveillance versus nephron-sparing surgery for a Bosniak IIF or III renal cyst: a cost-effectiveness analysis.

AJR Am J Roentgenol. 212: 830-838Miskin N. Qin L. Matalon S.A. et al.

Stratification of cystic renal masses into benign and potentially malignant: applying machine learning to the Bosniak classification.

Abdom Radiol. 46: 311-318

The Bosniak classification gets even better.

Radiology. 297: 606-607Winters B.R. Gore J.L. Holt S.K. et al.

Cystic renal cell carcinoma carries an excellent prognosis regardless of tumor size.

Urol Oncol. 33 (): 505Donin N.M. Mohan S. Pham H. et al.

Clinicopathologic outcomes of cystic renal cell carcinoma.

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Management of complex renal cysts in Canada: results of a survey study.

BMC Urol. 20https://doi.org/10.1186/s12894-020-00614-5Campbell S.C. Uzzo R.G. Karam J.A. et al.

Renal mass and localized renal cancer: evaluation, management, and follow-up: AUA Guideline: Part II.

J Urol. 206: 209-218

89Zr-TLX250 for PET/CT Imaging of ccRCC – ZIRCON Study. Clinical Trials.gov identifier: NCT03849118.

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The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.

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Tracking cancer evolution reveals constrained routes to metastases: TRACERx Renal.

Cell. 173 (): 581-594Turajlic S. Xu H. Litchfield K. et al.

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal.

Cell. 173 (): 595-610Nuzzo P.V. Berchuck J.E. Korthauer K. et al.

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes.

Nat Med. 26: 1041-1043

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