PACAP inhibition alleviates neuropathic pain by modulating Nav1.7 through the MAPK/ERK signaling pathway in a rat model of chronic constriction injury
Keywords
Trigeminal neuralgia
Neuropathic pain
Volt-gated sodium channels(VGSCs)
Pituitary adenylate cyclase-activating polypeptide(PACAP)
PAC1 receptor
MAPK/ERK
P-ERK
Infraorbital nerve chronic constriction injury(ION-CCI)
Intrathecal injection
Data availability
Data will be made available on request.
© 2023 The Authors. Published by Elsevier Ltd.
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