Hombach S, Kretz M. Non-coding RNAs: classification, biology and functioning. Adv Exp Med Biol. 2016;937:3–17.

CAS  Google Scholar 

Sevignani C, Calin GA, Siracusa LD, Croce CM. Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm Genome Off J Int Mamm Genome Soc. 2006;17(3):189–202.

CAS  Google Scholar 

Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433(7027):769–73.

CAS  Google Scholar 

Saliminejad K, Khorram Khorshid HR, Soleymani Fard S, Ghaffari SH. An overview of microRNAs: biology, functions, therapeutics, and analysis methods. J Cell Physiol. 2019;234(5):5451–65.

CAS  Google Scholar 

Ørom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell. 2008;30(4):460–71.

Google Scholar 

Liu B, Li J, Cairns MJ. Identifying miRNAs, targets and functions. Brief Bioinform. 2014;15(1):1–19.

Google Scholar 

Ratti M, Lampis A, Ghidini M, Salati M, Mirchev MB, Valeri N, et al. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside. Target Oncol. 2020;15(3):261–78.

Google Scholar 

Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res. 2008;79(4):581–8.

CAS  Google Scholar 

Roy PS, Saikia BJ. Cancer and cure: a critical analysis. Indian J Cancer. 2016;53(3):441–2.

CAS  Google Scholar 

Suhail Y, Cain MP, Vanaja K, Kurywchak PA, Levchenko A, Kalluri R, et al. Systems biology of cancer metastasis. Cell Syst. 2019;9(2):109–27.

CAS  Google Scholar 

Hill M, Tran N. miRNA interplay: mechanisms and consequences in cancer. Dis Models Mech. 2021;14(4):dmm047662.

CAS  Google Scholar 

Peng Y, Croce CM. The role of MicroRNAs in human cancer. Signal Transduct Target Ther. 2016;1(1):15004.

Google Scholar 

Acunzo M, Romano G, Wernicke D, Croce CM. MicroRNA and cancer–a brief overview. Adv Biol Regul. 2015;57:1–9.

CAS  Google Scholar 

Otmani K, Lewalle P. Tumor suppressor miRNA in cancer cells and the tumor microenvironment: mechanism of deregulation and clinical implications. Front Oncol. 2021;11:708765.

Google Scholar 

Magee RG, Telonis AG, Loher P, Londin E, Rigoutsos I. Profiles of miRNA isoforms and tRNA fragments in prostate cancer. Sci Rep. 2018;8(1):5314.

Google Scholar 

Tomasello L, Distefano R, Nigita G, Croce CM. The MicroRNA family gets wider: the IsomiRs classification and role. Front Cell Dev Biol. 2021;9: 668648.

Google Scholar 

Zelli V, Compagnoni C, Capelli R, Corrente A, Cornice J, Vecchiotti D, et al. Emerging role of isomiRs in cancer: state of the art and recent advances. Genes. 2021;12(9):1447.

CAS  Google Scholar 

Nunes DN, Dias-Neto E, Cardó-Vila M, Edwards JK, Dobroff AS, Giordano RJ, et al. Synchronous down-modulation of miR-17 family members is an early causative event in the retinal angiogenic switch. Proc Natl Acad Sci USA. 2015;112(12):3770–5.

CAS  Google Scholar 

Tanzer A, Stadler PF. Molecular evolution of a microRNA cluster. J Mol Biol. 2004;339(2):327–35.

CAS  Google Scholar 

Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008;132(5):875–86.

CAS  Google Scholar 

Huang W, Wu X, Xiang S, Qiao M, Cen X, Pan X, et al. Regulatory mechanism of miR-20a-5p expression in Cancer. Cell Death Discovery. 2022;8(1):262.

CAS  Google Scholar 

Basak J, Majsterek I. miRNA-Dependent CD4(+) T cell differentiation in the pathogenesis of multiple sclerosis. Multiple Sclerosis International. 2021;2021.

Zhou ZQ, Chen SW, Tian ZM, Deng SB, Yi XY, Yang SN, et al. miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1 alpha/NF-kappa B pathway. Acta Biochim Biophys Sin. 2020;52(9):927–34.

CAS  Google Scholar 

Wang RZ, Chopra N, Nho K, Maloney B, Obukhov AG, Nelson PT, et al. Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers. Mol Psychiatry. 2022;27(2):1256–73.

CAS  Google Scholar 

Xu MZ, Yu T. MiR-20b-5p contributes to the dysfunction of vascular smooth muscle cells by targeting MAGI3 in hypertension. J Mol Histol. 2022;53(2):187–97.

CAS  Google Scholar 

Lu Y, Wang SJ, Cai SY, Gu XX, Wang JJ, Yang Y, et al. Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia/re-oxygenation-induced endothelial autophagy in vitro. Cell Death Dis. 2020;11(8):1–4.

Google Scholar 

Zhang SS, Kan XQ, Liu P, Yin LZ, Li QY, Xu HY. MiR-20b is implicated in preeclampsia progression via the regulation of myeloid cell leukemin-1. J Biol Regul Homeost Agents. 2020;34(5):1709–17.

CAS  Google Scholar 

Tang J, Luo LY. MicroRNA-20b-5p inhibits platelet-derived growth factor-induced proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3. Biomed Pharmacother. 2018;102:34–40.

CAS  Google Scholar 

Jin MY, Li HY, Xu HF, Huo GX, Yao YY. MicroRNA-20b inhibits trophoblast cell migration and invasion by targeting MMP-2. Int J Clin Exp Pathol. 2017;10(11):10901–9.

Google Scholar 

Xin YZ, Cai HF, Lu TY, Zhang Y, Yang Y, Cui YB. miR-20b Inhibits T Cell proliferation and activation via NFAT signaling pathway in thymoma-associated myasthenia gravis. Biomed Res Int. 2016;2016.

Wang HY, Ban WR, Wang T, Li Z, Dang XQ. miR-20b/106a modulate Ngn2 gene expression during neural differentiation of human umbilical cord mesenchymal stem cells. NeuroReport. 2017;28(18):1225–31.

CAS  Google Scholar 

Mu GH, Deng YJ, Lu ZQ, Li X, Chen YB. miR-20b suppresses mitochondrial dysfunction-mediated apoptosis to alleviate hyperoxia-induced acute lung injury by directly targeting MFN1 and MFN2. Acta Biochim Biophys Sin. 2021;53(2):220–8.

CAS  Google Scholar 

Zhu SH, Hu XS, Yu ZB, Peng YZ, Zhu JG, Liu XH, et al. Effect of miR-20b on apoptosis, differentiation, the bmp signaling pathway and mitochondrial function in the P19 cell model of cardiac differentiation in vitro. PLoS ONE. 2015;10(4):e0123519.

Google Scholar 

He WD, Cheng Y. Inhibition of miR-20 promotes proliferation and autophagy in articular chondrocytes by PI3K/AKT/mTOR signaling pathway. Biomed Pharmacother. 2018;97:607–15.

CAS  Google Scholar 

Cui Y, Han J, Xiao ZF, Chen T, Wang B, Chen B, et al. The miR-20-Rest-Wnt signaling axis regulates neural progenitor cell differentiation. Sci Rep. 2016;6:1–3.

CAS  Google Scholar 

Liang B, Wang X, Song XS, Bai R, Yang HY, Yang ZM, et al. MicroRNA-20a/b regulates cholesterol efflux through post-transcriptional repression of ATP-binding cassette transporter A1. BBA-Mol Cell Biol L. 2017;1862(9):929–38.

CAS  Google Scholar 

Pernaute B, Spruce T, Smith KM, Sanchez-Nieto JM, Manzanares M, Cobb B, et al. MicroRNAs control the apoptotic threshold in primed Pluripotent stem cells through regulation of BIM. Genes Dev. 2014;28(17):1873–8.

CAS  Google Scholar 

Ghafouri-Fard S, Niazi V, Taheri M. Role of miRNAs and lncRNAs in hematopoietic stem cell differentiation. Non-Coding Rna Res. 2021;6(1):8–14.

CAS  Google Scholar 

Zaiou M, Rihn BH, Bakillah A. Epigenetic regulation of genes involved in the reverse cholesterol transport through interaction with miRNAs. Front Biosci-Landmark. 2018;23:2090–105.

CAS  Google Scholar 

Tai LH, Huang CJ, Choo KB, Cheong SK, Kamarul T. Oxidative stress down-regulates MiR-20b-5p, MiR-106a-5p and E2F1 expression to suppress the G1/S transition of the cell cycle in multipotent stromal cells. Int J Med Sci. 2020;17(4):457–70.

CAS  Google Scholar 

Dong FF, Dong SH, Liang Y, Wang K, Qin YW, Zhao XX. miR-20b inhibits the senescence of human umbilical vein endothelial cells through regulating the Wnt/beta-catenin pathway via the TXNIP/NLRP3 axis. Int J Mol Med. 2020;45(3):847–57.

CAS  Google Scholar 

Robichaud K, Craig PM. Nuclear microRNAs may regulate mitochondrial gene expression following effluent exposure in darter (Etheostoma) species. Comp Biochem Physiol B-Biochem Mol Biol. 2022;262:110754.

CAS  Google Scholar 

Cui JX, Gu LP, Zhong LC, Liu XZ, Sun YN, Xu TJ. microRNA-20–1 and microRNA-101a suppress the NF-kappa B-mediated inflammation production by targeting TRAF6 in Miiuy croaker. Infect Immun. 2022;90(1):e00585.

CAS  Google Scholar 

Zhang MJ, Yin JW, Wu JH, Gu J, Yuan CY, Miao HJ, et al. Circular RNAs are abundant and dynamically expressed during the embryonic lung development of C57BL/6 mice. Heliyon. 2020;6(3):e03437.

CAS  Google Scholar 

Cheng Y-C, Chiang H-Y, Cheng S-J, Chang H-W, Li Y-J, Shieh S-Y. Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation. Cell Death Dis. 2020;11(12):1046.

CAS  Google Scholar 

Lou J, Wang YL, Zhang ZM, Qiu WQ. MiR-20b inhibits mycobacterium tuberculosis induced inflammation in the lung of mice through targeting NLRP3. Exp Cell Res. 2017;358(2):120–8.

CAS  Google Scholar 

Ma H, Wang HL, Luo YL, Guo SJ, Song CW. Mir-20b-induced increase in myeloid-derived suppressor cells in the lungs of mice with chronic asthma. Ann Clin Lab Sci. 2017;47(1):76–82.

CAS  Google Scholar 

Shi J, Duan JY, Gong HJ, Pang YW, Wang L, Yan YJ. Exosomes from miR-20b-3p-overexpressing stromal cells ameliorate calcium oxalate deposition in rat kidney. J Cell Mol Med. 2019;23(11):7268–78.

CAS  Google Scholar 

You HP, Zhang LH, Chen ZY, Liu WF, Wang HG, He HF. MiR-20b-5p relieves neuropathic pain by targeting Akt3 in a chronic constriction injury rat model. Synapse. 2019;73(12):e22125.

CAS  Google Scholar 

Tang GX, Yang MS, Xiang KM, Yang BC, Liu ZL, Zhao SP. MiR-20b-5p modulates inflammation, apoptosis and angiogenesis in severe acute pancreatitis through autophagy by targeting AKT3. Autoimmunity. 2021;54(7):460–70.

CAS  Google Scholar 

Liang ZG, Yao H, Xie RS, Gong CL, Tian Y. MicroRNA-20b-5p promotes ventricular remodeling by targeting the TGF beta-/Smad signaling pathway in a rat model of ischemia-reperfusion injury. Int J Mol Med. 2018;42(2):975–87.

CAS  Google Scholar 

Liu J, Liu YA, Zhang LD, Chen YZ, Du HX, Wen ZL, et al. Down-regulation of circDMNT3B is conducive to intestinal mucosal permeability dysfunction of rats with sepsis via sponging miR-20b-5p. J Cell Mol Med. 2020;24(12):6731–40.

CAS  Google Scholar 

O’Brien J, Hayder H, Zayed Y, Peng C. Overview of MicroRNA biogenesis, mechanisms of actions, and circulation. Front Genet. 2018;9:402.

CAS  Google Scholar 

Tirosh I, Bilu Y, Barkai N. Comparative biology: beyond sequence analysis. Curr Opin Biotechnol. 2007;18(4):371–7.

CAS  Google Scholar 

Morandin C, Tin MMY, Abril S, Gómez C, Pontieri L, Schiøtt M, et al. Comparative transcriptomics reveals the conserved building blocks involved in parallel evolution of diverse phenotypic traits in ants. Genome Biol. 2016;17(1):43.

Google Scholar 

Warnefors M, Liechti A, Halbert J, Valloton D, Kaessmann H. Conserved microRNA editing in mammalian evolution, development and disease. Genome Biol. 2014;15(6):R83.