Karagiannidis C, Brodie D, Strassmann S, Stoelben E, Philipp A, Bein T, et al. Extracorporeal membrane oxygenation: evolving epidemiology and mortality. Intensive Care Med. 2016;42(5):889–96.

Article  Google Scholar 

Thiagarajan RR, Barbaro RP, Rycus PT, McMullan DM, Conrad SA, Fortenberry JD, et al. Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J. 2017;63(1):60–7.

Article  Google Scholar 

Rilinger J, Krötzsch K, Bemtgen X, Jäckel M, Zotzmann V, Lang CN, et al. Long-term survival and health-related quality of life in patients with severe acute respiratory distress syndrome and veno-venous extracorporeal membrane oxygenation support. Crit Care. 2021;25(1):1–11.

Article  Google Scholar 

Thomas J, Kostousov V, Teruya J. Bleeding and Thrombotic Complications in the Use of Extracorporeal Membrane Oxygenation. Semin Thromb Hemost. 2018;44(1):20–9.

Article  Google Scholar 

Murphy DA, Hockings LE, Andrews RK, Aubron C, Gardiner EE, Pellegrino VA, et al. Extracorporeal membrane oxygenation-hemostatic complications. Transfus Med Rev. 2015;29(2):90–101.

Article  Google Scholar 

Abrams D, Baldwin MR, Champion M, Agerstrand C, Eisenberger A, Bacchetta M, et al. Thrombocytopenia and extracorporeal membrane oxygenation in adults with acute respiratory failure: a cohort study. Intensive Care Med. 2016;42(5):844–52.

Article  Google Scholar 

Siegel PM, Chalupsky J, Olivier CB, Bojti I, Pooth JS, Trummer G, et al. Early platelet dysfunction in patients receiving extracorporeal membrane oxygenation is associated with mortality. J Thromb Thrombolysis. 2022;53(3):712–21.

Article  Google Scholar 

Karkouti K, Ho LTS. Preventing and managing catastrophic bleeding during extracorporeal circulation. Hematol (United States). 2018;2018(1):522–9.

Google Scholar 

Kalbhenn J, Schlagenhauf A, Rosenfelder S, Schmutz A, Zieger B. Acquired von Willebrand syndrome and impaired platelet function during venovenous extracorporeal membrane oxygenation: Rapid onset and fast recovery. J Hear Lung Transplant. 2018;37(8):985–91.

Article  Google Scholar 

Schlagenhauf A, Kalbhenn J, Geisen U, Beyersdorf F, Zieger B. Acquired von Willebrand Syndrome and Platelet Function Defects during Extracorporeal Life Support (Mechanical Circulatory Support). Hamostaseologie. 2020;40(2):221–5.

Article  Google Scholar 

Bortot M, Ashworth K, Sharifi A, Walker F, Crawford NC, Neeves KB, et al. Turbulent Flow Promotes Cleavage of VWF (von Willebrand Factor) by ADAMTS13 (A Disintegrin and Metalloproteinase With a Thrombospondin Type-1 Motif, Member 13). Arterioscler Thromb Vasc Biol. 2019;39(9):1831–42.

Article  Google Scholar 

Peyvandi F, Mamaev A, Wang JD, Stasyshyn O, Timofeeva M, Curry N, et al. Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery. J Thromb Haemost. 2019;17(1):52–62.

Article  Google Scholar 

Sharma R, Flood VH. Advances in the diagnosis and treatment of Von Willebrand disease. Blood. 2017;130(22):2386–91.

Article  Google Scholar 

Posan E, McBane RD, Grill DE, Motsko CL, Nichols WL. Comparison of PFA-100 testing and bleeding time for detecting platelet hypofunction and von Willebrand disease in clinical practice. Thromb Haemost. 2003;90(3):483–90.

Article  Google Scholar 

Fressinaud E, Veyradier A, Truchaud F, Martin I, Boyer-Neumann C, Trossaert M, et al. Screening for von Willebrand disease with a new analyzer using high shear stress: A study of 60 cases. Blood. 1998;91(4):1325–31.

Article  Google Scholar 

Schulman S, Kearon C, Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost. 2005;3(4):692–4.

Article  Google Scholar 

Conrad SA, Broman LM, Taccone FS, Lorusso R, Malfertheiner MV, Pappalardo F, et al. The extracorporeal life support organization Maastricht treaty for nomenclature in extracorporeal life support a position paper of the extracorporeal life support organization. Am J Respir Crit Care Med. 2018;198(4):447–51.

Article  Google Scholar 

Broman LM, Taccone FS, Lorusso R, Malfertheiner MV, Pappalardo F, DI Nardo M, et al. The ELSO Maastricht Treaty for ECLS Nomenclature: Abbreviations for cannulation configuration in extracorporeal life support - A position paper of the Extracorporeal Life Support Organization. Crit Care. 2019;23(1):1–9.

Article  Google Scholar 

Siegel PM, Orlean L, Bojti I, Kaier K, Witsch T, Esser JS, et al. Monocyte Dysfunction Detected by the Designed Ankyrin Repeat Protein F7 Predicts Mortality in Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation. Front Cardiovasc Med. 2021;8(July):1–12.

Google Scholar 

Staudacher DL, Gold W, Biever PM, Bode C, Wengenmayer T. Early fluid resuscitation and volume therapy in venoarterial extracorporeal membrane oxygenation. J Crit Care. 2017;37:130–5.

Article  Google Scholar 

Heilmann C, Geisen U, Beyersdorf F, Nakamura L, Benk C, Trummer G, et al. Acquired von Willebrand syndrome in patients with extracorporeal life support (ECLS). Intensive Care Med. 2012;38(1):62–8.

Article  Google Scholar 

Favaloro EJ, Mohammed S, Vong R, Chapman K, Kershaw G, Just S, et al. Harmonizing platelet function analyzer testing and reporting in a large laboratory network. Int J Lab Hematol. 2022;44(5):934–44.

Article  Google Scholar 

Pekrul I, Kragh T, Turecek PL, Novack AR, Ott HW, Spannagl M. Sensitive and specific assessment of recombinant von Willebrand factor in platelet function analyzer. Platelets. 2019;30(2):264–70.

Article  Google Scholar 

Panholzer B, Bajorat T, Haneya A, Kowalski D, Juhl D, Rocke A, et al. Acquired von Willebrand syndrome in ECMO patients: A 3-year cohort study. Blood Cells Mol Dis. 2021;87:102526. Available from: http://www.ncbi.nlm.nih.gov/pubmed/33338698.

Article  Google Scholar 

Kalbhenn J, Glonnegger H, Büchsel M, Priebe H, Zieger B. Acquired von Willebrand Syndrome and Desmopressin Resistance During Venovenous Extracorporeal Membrane Oxygenation in Patients With COVID-19: A Prospective Observational Study. Crit Care Med. 2022;50(8):1246–55.

Article  Google Scholar 

Favaloro EJ, Pasalic L, Lippi G. Towards 50 years of platelet function analyser ( PFA ) testing. 2022. p. 1–10.

Google Scholar 

Kundu SK, Heilmann EJ, Sio R, Garcia C, Davidson RM, Ostgaard RA. Description of an in vitro platelet function analyzer - PFA-100®. Semin Thromb Hemost. 1995;21(SUPPL. 2):106–12.

Google Scholar 

Favaloro EJ, Kershaw G, Bukuya M, Hertzberg M, Koutts J. Laboratory diagnosis of von Willebrand disorder (vWD) and monitoring of DDAVP therapy: Efficacy of the PFA-100® and vWF:CBA as combined diagnostic strategies. Haemophilia. 2001;7(2):180–9.

Article  Google Scholar 

Cattaneo M, Federici AB, Lecchi A, Agati B, Lombardi R, Stabile F, et al. Evaluation of the PFA-100 system in the diagnosis and therapeutic monitoring of patients with von Willebrand disease. Thromb Haemost. 1999;82(1):35–9.

Google Scholar 

Franchini M, Gandini G, Manzato F, Lippi G. Evaluation of the PFA-100 system for monitoring desmopressin therapy in patients with type 1 von Willebrand’s disease. Haematologica. 2002;87(6):670.

Google Scholar 

Budde U, Metzner HJ, Müller HG. Comparative analysis and classification of von Willebrand factor/factor VIII concentrates: Impact on treatment of patients with von Willebrand disease. Semin Thromb Hemost. 2006;32(6):626–35.

Article  Google Scholar 

Rajpurkar M, Frey MJ, Sabo C, Hollon W. Recombinant von Willebrand factor concentrate in 2A von Willebrand disease: Comparison to plasma-derived von Willebrand factor concentrate therapy. Blood Coagul Fibrinolysis. 2019;30(4):168–70.

Article  Google Scholar 

Mazzeffi M, Henderson R, Krause E, Rabin J, Madathil R, Chow J, et al. In Vitro Comparison of Recombinant and Plasma- Derived von Willebrand Factor Concentrate for Treatment of Acquired von Willebrand Syndrome in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 2022;134(2):312–21.

Article  Google Scholar 

Helms J, Tacquard C, Severac F, Leonard-Lorant I, Ohana M, Delabranche X, et al. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med. 2020;46(6):1089–98.

Article  Google Scholar 

Escher R, Breakey N, Lämmle B. ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients. Thromb Res. 2020;192(April):174–5.

Article  Google Scholar 

Supady A, Combes A, Barbaro RP, Camporota L, Diaz R, Fan E, et al. Respiratory indications for ECMO: focus on COVID-19. Intensive Care Med. 2022;48(10):1326–37. Available from: https://doi.org/10.1007/s00134-022-06815-w.

Article  Google Scholar 

Mazzeffi M, Bathula A, Tabatabai A, Menaker J, Kaczorowski D, Madathil R, et al. Von Willebrand Factor Concentrate Administration for Acquired Von Willebrand Syndrome- Related Bleeding During Adult Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. 2021;35(3):882–7.

Article  Google Scholar 

Tiede A, Rand JH, Budde U, Ganser A, Federici AB. How I treat the acquired von Willebrand syndrome. Blood. 2011;117(25):6777–85.

Article  Google Scholar 

Favaloro EJ. Clinical utility of the PFA-100. Semin Thromb Hemost. 2008;34(8):709–33.

Article  Google Scholar 

Cho YU, Chi HS, Jang S, Park CJ. Reconfirmation of preanalytical variables and establishment of reference intervals of platelet function analyzer-100 closure times in Korean adults. Korean J Lab Med. 2007;27(5):318–23.

Google Scholar