J.C.H. receives research support from the Frederick J. and Theresa Dow Wallace Fund of the New York Community Trust and also receives salary support from NIH (R01 CA241758, R01 CA259173 and R01 CA273031), PCORI CER-2019C1-15682 and CER-2019C2-17372, and a Prostate Cancer Foundation Challenge Award. The other authors declare no competing interests.