Supported by the National Institutes of Health/National Heart, Lung, Blood Institute grants: NIH/NHLBI R01HL128970 (V.Y.P.), R01HL133100 (V.Y.P.), R01HL138932 (V.Y.P.), R61HL156240 (V.Y.P.), NIDA U18DA052301 (V.Y.P.), NIH/National Institute of Neurological Disorders and Stroke 1R01NS112019 (E.V.B.); São Paulo Research Foundation (FAPESP) grant 2018/08758-3 (C.F.); American Heart Association Postdoctoral Fellowship Award #827943 (C.F.); Eshelman Institute for innovation grant UNC RX03812420 (A.V.K.); and the Carolina Partnership, a strategic partnership between the University of North Carolina Eshelman School of Pharmacy and The University Cancer Research Fund (A.V.K.).

Author Contributions: C.F.: conceptualization, data curation, investigation, methodology, project administration, visualization, and writing; J.D.R.: conceptualization, data curation, investigation, methodology, validation, visualization, and writing; H.P.: conceptualization, data curation, investigation, methodology, and validation; R.K.: investigation and methodology; Y.Z.: data curation and investigation; L.K.: formal analysis and investigation; F.A.-D.: investigation and methodology; S.B.: conceptualization and investigation; R.S.A.: methodology, supervision, and writing; E.V.B.: conceptualization, data curation, funding acquisition, formal analysis, methodology, project administration, supervision, visualization, writing-original draft, and writing; A.V.K.: conceptualization, funding acquisition, methodology, project administration, supervision, and writing; and V.Y.P.: conceptualization, funding acquisition, methodology, project administration, supervision, and writing.

This letter has a data supplement, which is accessible from this issue’s table of contents at www.atsjournals.org.