Antoniou T, Macdonald EM, Hollands S, Gomes T, Mamdani MM, Garg AX, et al. Proton pump inhibitors and the risk of acute kidney injury in older patients: a population-based cohort study. CMAJ Open. 2015;3(2):E166–71.

Article  PubMed  PubMed Central  Google Scholar 

Klepser DG, Collier DS, Cochran GL. Proton pump inhibitors and acute kidney injury: a nested case-control study. BMC Nephrol. 2013;14:150.

Article  PubMed  PubMed Central  Google Scholar 

Blank ML, Parkin L, Paul C, Herbison P. A nationwide nested case-control study indicates an increased risk of acute interstitial nephritis with proton pump inhibitor use. Kidney Int. 2014;86(4):837–44.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hart E, Dunn TE, Feuerstein S, Jacobs DM. Proton pump inhibitors and risk of acute and chronic kidney disease: a retrospective cohort study. Pharmacotherapy. 2019;39(4):443–53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh J, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med. 2016;176(2):238–46.

Article  PubMed  PubMed Central  Google Scholar 

Klatte DCF, Gasparini A, Xu H, de Deco P, Trevisan M, Johansson ALV, et al. Association between proton pump inhibitor use and risk of progression of chronic kidney disease. Gastroenterology. 2017;153(3):702–10.

Article  CAS  PubMed  Google Scholar 

Xie Y, Bowe B, Li T, Xian H, Yan Y, Al-Aly Z. Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury. Kidney Int. 2017;91(6):1482–94.

Article  CAS  PubMed  Google Scholar 

Xie Y, Bowe B, Li T, Xian H, Balasubramanian S, Al-Aly Z. Proton pump inhibitors and risk of incident CKD and progression to ESRD. J Am Soc Nephrol. 2016;27(10):3153–63.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee J, Mark RG, Celi LA, Danziger J. Proton pump inhibitors are not associated with acute kidney injury in critical illness. J Clin Pharmacol. 2016;56(12):1500–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, Xiong M, Yang M, Wang L, Nie S, Liu D, et al. Proton pump inhibitors and the risk of hospital-acquired acute kidney injury in children. Ann Transl Med. 2020;8(21):1438.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liabeuf S, Lambert O, Metzger M, Hamroun A, Laville M, Laville SM, et al. Adverse outcomes of proton pump inhibitors in patients with chronic kidney disease: the CKD-REIN cohort study. Br J Clin Pharmacol. 2021;87(7):2967–76.

Article  CAS  PubMed  Google Scholar 

Ikuta K, Nakagawa S, Momo K, Yonezawa A, Itohara K, Sato Y, et al. Association of proton pump inhibitors and concomitant drugs with risk of acute kidney injury: a nested case-control study. BMJ Open. 2021;11(2):e041543.

Article  PubMed  PubMed Central  Google Scholar 

Hwang YJ, Shariff SZ, Gandhi S, Wald R, Clark E, Fleet JL, et al. Validity of the international classification of diseases, tenth revision code for acute kidney injury in elderly patients at presentation to the emergency department and at hospital admission. BMJ Open. 2012;2(6):e001821.

Article  PubMed  PubMed Central  Google Scholar 

Woodruff AE, Meaney CJ, Hansen EA, Prescott GM. Azithromycin-induced, biopsy-proven acute interstitial nephritis in an adult successfully treated with low-dose corticosteroids. Pharmacotherapy. 2015;35(11):e169–74.

Article  CAS  PubMed  Google Scholar 

Gandhi S, Fleet JL, Bailey DG, McArthur E, Wald R, Rehman F, et al. Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury. JAMA. 2013;310(23):2544–53.

Article  CAS  PubMed  Google Scholar 

Li DQ, Kim R, McArthur E, Fleet JL, Bailey DG, Juurlink D, et al. Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4. CMAJ. 2015;187(3):174–80.

Article  PubMed  PubMed Central  Google Scholar 

Furuta T, Ohashi K, Kobayashi K, Iida I, Yoshida H, Shirai N, et al. Effects of clarithromycin on the metabolism of omeprazole in relation to CYP2C19 genotype status in humans. Clin Pharmacol Ther. 1999;66(3):265–74.

Article  CAS  PubMed  Google Scholar 

Miura M, Tada H, Yasui-Furukori N, Uno T, Sugawara K, Tateishi T, et al. Effect of clarithromycin on the enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes. Chirality. 2005;17(6):338–44.

Article  CAS  PubMed  Google Scholar 

Hassan-Alin M, Andersson T, Niazi M, Liljeblad M, Persson BA, Röhss K. Studies on drug interactions between esomeprazole, amoxicillin and clarithromycin in healthy subjects. Int J Clin Pharmacol Ther. 2006;44(3):119–27.

Article  CAS  PubMed  Google Scholar 

Whitaker HJ, Farrington CP, Spiessens B, Musonda P. Tutorial in biostatistics: the self-controlled case series method. Stat Med. 2006;25(10):1768–97.

Article  PubMed  Google Scholar 

Petersen I, Douglas I, Whitaker H. Self controlled case series methods: an alternative to standard epidemiological study designs. BMJ. 2016;354:i4515.

Article  PubMed  Google Scholar 

Hiragi S, Yamada H, Tsukamoto T, Yoshida K, Kondo N, Matsubara T, et al. Acetaminophen administration and the risk of acute kidney injury: a self-controlled case series study. Clin Epidemiol. 2018;10:265–76.

Article  PubMed  PubMed Central  Google Scholar 

Selby NM, Hill R, Fluck RJ. Standardizing the early identification of acute kidney injury: the NHS England National Patient Safety Alert. Nephron. 2015;131(2):113–7.

Article  PubMed  Google Scholar 

Sato N, Uchino E, Kojima R, Hiragi S, Yanagita M, Okuno Y. Prediction and visualization of acute kidney injury in intensive care unit using one-dimensional convolutional neural networks based on routinely collected data. Comput Methods Prog Biomed. 2021;206:106129.

Article  Google Scholar 

Fliser D, Laville M, Covic A, Fouque D, Vanholder R, Juillard L, et al. A European renal best practice (ERBP) position statement on the kidney disease improving global outcomes (KDIGO) clinical practice guidelines on acute kidney injury: part 1: definitions, conservative management and contrast-induced nephropathy. Nephrol Dial Transplant. 2012;27(12):4263–72.

Article  PubMed  PubMed Central  Google Scholar 

Isik B, Alexander MP, Manohar S, Vaughan L, Kottschade L, Markovic S, et al. Biomarkers, clinical features, and Rechallenge for immune checkpoint inhibitor renal immune-related adverse events. Kidney Int Rep. 2021;6(4):1022–31.

Article  PubMed  PubMed Central  Google Scholar 

Mansfield KE, Douglas IJ, Nitsch D, Thomas SL, Smeeth L, Tomlinson LA. Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis. Clin Epidemiol. 2018;10:187–202.

Article  PubMed  PubMed Central  Google Scholar 

Grams ME, Sang Y, Ballew SH, Gansevoort RT, Kimm H, Kovesdy CP, et al. A Meta-analysis of the Association of Estimated GFR, albuminuria, age, race, and sex with acute kidney injury. Am J Kidney Dis. 2015;66(4):591–601.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lafrance JP, Miller DR. Acute kidney injury associates with increased long-term mortality. J Am Soc Nephrol. 2010;21(2):345–52.

Article  PubMed  PubMed Central  Google Scholar 

Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16(11):3365–70.

Article  PubMed  Google Scholar 

Helsby NA, Lo WY, Simpson IJ, Voss DM, Logan KE, Searle M, et al. Omeprazole-induced acute interstitial nephritis is not related to CYP2C19 genotype or CYP2C19 phenotype. Br J Clin Pharmacol. 2010;69(5):516–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Leonard CE, Freeman CP, Newcomb CW, Reese PP, Herlim M, Bilker WB, et al. Proton pump inhibitors and traditional nonsteroidal anti-inflammatory drugs and the risk of acute interstitial nephritis and acute kidney injury. Pharmacoepidemiol Drug Saf. 2012;21(11):1155–72.

Article  CAS  PubMed  Google Scholar 

Sierra F, Suarez M, Rey M, Vela MF. Systematic review: proton pump inhibitor-associated acute interstitial nephritis. Aliment Pharmacol Ther. 2007;26(4):545–53.

Article  CAS  PubMed  Google Scholar 

Raghavan R, Shawar S. Mechanisms of drug-induced interstitial nephritis. Adv Chronic Kidney Dis. 2017;24(2):64–71.

Article  PubMed  Google Scholar 

Weersma RK, Zhernakova A, Fu J. Interaction between drugs and the gut microbiome. Gut. 2020;69(8):1510–9.

Article  CAS  PubMed  Google Scholar