Aligning Dentato-Rubro-Thalamic Tract and Subthalamic Nucleus Targets in a Patient with Comorbid Essential Tremor and Parkinson’s Disease: Case Report

Stereotactic and Functional Neurosurgery

Boogers A.a,b· Van Bogaert T.a· Peeters J.a· Kilic U.c· Sunaert S.d· Vandenberghe W.b,e· Mc Laughlin M.a· De Vloo P.c,f· Nuttin B.c,f

Author affiliations

aExperimental Oto-Rhino-Laryngology, Department of Neurosciences, KU Leuven, Leuven, Belgium
bDepartment of Neurology, UZ Leuven, Leuven, Belgium
cExperimental Neurosurgery and Neuroanatomy, Department of Neurosciences, KU Leuven, Leuven, Belgium
dDepartment of Radiology, UZ Leuven, Leuven, Belgium
eLaboratory for Parkinson Research, Department of Neurosciences, KU Leuven, Leuven, Belgium
fDepartment of Neurosurgery, UZ Leuven, Leuven, Belgium

Stereotact Funct Neurosurg

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Article / Publication Details

First-Page Preview

Abstract of Case Report

Received: July 13, 2022
Accepted: September 09, 2022
Published online: November 29, 2022

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN

Abstract

Deep brain stimulation is an established treatment option for both essential tremor (ET) and Parkinson’s disease (PD), although typically targeting different brain structures. Some patients are diagnosed with comorbid ET and PD. Selecting the optimal stimulation target in these patients is challenging. We present a patient with comorbid ET and PD in whom we used bilaterally a single parietal trajectory to align the dentato-rubro-thalamic tract and the subthalamic nucleus. Although parietal trajectories are challenging, we reached satisfactory outcomes for both conditions without complications. Single-electrode deep brain stimulation of the dentato-rubro-thalamic tract and the subthalamic nucleus through a parietal approach may represent a feasible treatment option in this patient group.

© 2022 S. Karger AG, Basel

References Lozano AM, Lipsman N, Bergman H, Brown P, Chabardes S, Chang JW, et al. Deep brain stimulation: current challenges and future directions. Nat Rev Neurol. 2019;15(3):148–60. Tysnes OB, Storstein A. Epidemiology of Parkinson’s disease. J Neural Transm. 2017;124(8):901–5. Lee JW, Song YS, Kim H, Ku BD, Lee WW. Alteration of tremor dominant and postural instability gait difficulty subtypes during the progression of Parkinson’s disease: analysis of the PPMI cohort. Front Neurol. 2019;10:471–8. Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord. 2010;25(5):534–41. Fekete R, Jankovic J. Revisiting the relationship between essential tremor and Parkinson’s disease. Mov Disord. 2011;26(3):391–8. Nowacki A, Debove I, Rossi F, Schlaeppi JA, Petermann K, Wiest R, et al. Targeting the posterior subthalamic area for essential tremor: proposal for MRI-based anatomical landmarks. J Neurosurg. 2018;131(3):820–7. Tarakad A, Jankovic J. Essential tremor and Parkinson’s disease: exploring the relationship. Tremor Other Hyperkinet Mov. 2019;8(0):589. Baumann CR, Imbach LL, Baumann-Vogel H, Uhl M, Sarnthein J, Sürücü O. Interleaving deep brain stimulation for a patient with both Parkinson’s disease and essential tremor. Mov Disord. 2012;27(13):1700–1. Falconer RA, Rogers SL, Shenai M. Using directional deep brain stimulation to co-activate the subthalamic nucleus and zona incerta for overlapping essential tremor/Parkinson’ s disease symptoms. Front Neurol. 2018;9:544–13. Listik C, Santiago N, Reis PR, Godinho F, Duarte K, Teixeira MJ, et al. Targeting the hot spot in a patient with essential tremor and Parkinson’s disease: tractography matters. Clin Neurol Neurosurg. 2018;174:230–2. Wadhwa A, Schaefer S, Gerrard J, Deeb W, Okun MS, Patel A. Deep brain stimulation target selection in co-morbid essential tremor and Parkinson’s disease. Tremor Other Hyperkinet Mov. 2020;10:17. Radwan AM, Sunaert S, Schilling K, Descoteaux M, Landman BA, Vandenbulcke M, et al. An atlas of white matter anatomy, its variability, and reproducibility based on constrained spherical deconvolution of diffusion MRI. Neuroimage. 2022;254:119029. Horn A, Kühn AA. Lead-DBS: a toolbox for deep brain stimulation electrode localizations and visualizations. Neuroimage. 2015;107:127–35. Middlebrooks EH, Domingo RA, Vivas-Buitrago T, Okromelidze L, Tsuboi T, Wong JK, et al. Neuroimaging advances in deep brain stimulation: review of indications, anatomy, and brain connectomics. Am J Neuroradiol. 2020;41(9):1558–68. Ewert S, Plettig P, Li N, Chakravarty MM, Collins DL, Herrington TM, et al. Toward defining deep brain stimulation targets in MNI space: a subcortical atlas based on multimodal MRI, histology and structural connectivity. Neuroimage. 2018;170:271–82. Buijink AWG, Contarino MF, Koelman JHTM, Speelman JD, van Rootselaar AF. How to tackle tremor: systematic review of the literature and diagnostic work-up. Front Neurol. 2012;3:146. Neudorfer C, Hinzke M, Hunsche S, El Majdoub F, Lozano A, Maarouf M. Combined deep brain stimulation of subthalamic nucleus and ventral intermediate thalamic nucleus in tremor-dominant Parkinson’s disease using a parietal approach. Neuromodulation. 2019;22(4):493–502. Coenen VA, Rijntjes M, Prokop T, Piroth T, Amtage F, Urbach H, et al. One-pass deep brain stimulation of dentato-rubro-thalamic tract and subthalamic nucleus for tremor-dominant or equivalent type Parkinson’s disease. Acta Neurochir. 2016;158(4):773–81. Oertel MF, Schüpbach WMM, Ghika JA, Stieglitz LH, Fiechter M, Kaelin-Lang A, et al. Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson’s disease. Acta Neurochir. 2017;159(2):265–9. Stover NP, Okun MS, Evatt ML, Raju DV, Bakay RAE, Vitek JL. Stimulation of the subthalamic nucleus in a patient with Parkinson disease and essential tremor. Arch Neurol. 2005;62(1):141–3. Wijemanne S, Waln O, Shahed JJ. Concurrent bilateral vim and STN DBS in a patient with ET/PD. Neurology. 2014;82:P7.055. Article / Publication Details

First-Page Preview

Abstract of Case Report

Received: July 13, 2022
Accepted: September 09, 2022
Published online: November 29, 2022

Number of Print Pages: 6
Number of Figures: 2
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN

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