Lissek S, van Meurs B. Learning models of PTSD: Theoretical accounts and psychobiological evidence. Int J Psychophysiol: Off J Int Organ Psychophysiol. 2015;98:594–605.
Lissek S, Grillon C. Learning Models of PTSD. The Oxford Handbook of Traumatic Stress Disorders, 1st edn 2012.
Der-Avakian A, Mazei-Robison MS, Kesby JP, Nestler EJ, Markou A. Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response. Biol Psychiatry. 2014;76:542–9.
Article CAS PubMed PubMed Central Google Scholar
Kline AC, Cooper AA, Rytwinksi NK, Feeny NC. Long-term efficacy of psychotherapy for posttraumatic stress disorder: A meta-analysis of randomized controlled trials. Clin Psychol Rev. 2018;59:30–40.
Watts BV, Schnurr PP, Mayo L, Young-Xu Y, Weeks WB, Friedman MJ. Meta-analysis of the efficacy of treatments for posttraumatic stress disorder. J Clin psychiatry. 2013;74:e541–50.
Morina N, Wicherts JM, Lobbrecht J, Priebe S. Remission from post-traumatic stress disorder in adults: A systematic review and meta-analysis of long term outcome studies. 2014;34:249–55.
Markowitz S, Fanselow M. Exposure Therapy for Post-Traumatic Stress Disorder: Factors of Limited Success and Possible Alternative Treatment. Brain Sci. 2020;10:167.
Lammel S, Lim BK, Malenka RC. Reward and aversion in a heterogeneous midbrain dopamine system. Neuropharmacology. 2014;76:351–9.
Article CAS PubMed Google Scholar
Morales M, Margolis EB. Ventral tegmental area: cellular heterogeneity, connectivity and behaviour. Nat Rev Neurosci. 2017;18:73–85.
Article CAS PubMed Google Scholar
Morales M, Root DH. Glutamate neurons within the midbrain dopamine regions. Neuroscience. 2014;282:60–8.
Article CAS PubMed Google Scholar
Tan KR, Yvon C, Turiault M, Mirzabekov JJ, Doehner J, Labouebe G, et al. GABA neurons of the VTA drive conditioned place aversion. Neuron. 2012;73:1173–83.
Article CAS PubMed PubMed Central Google Scholar
Lammel S, Lim BK, Ran C, Huang KW, Betley MJ, Tye KM, et al. Input-specific control of reward and aversion in the ventral tegmental area. Nature. 2012;491:212–7.
Article CAS PubMed PubMed Central Google Scholar
Root DH, Mejias-Aponte CA, Qi J, Morales M. Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning. J Neurosci. 2014;34:13906–10.
Article PubMed PubMed Central Google Scholar
Barbano MF, Wang HL, Zhang S, Miranda-Barrientos J, Estrin DJ, Figueroa-Gonzalez A, et al. VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors. Neuron. 2020;107:368–82.e368
Article CAS PubMed PubMed Central Google Scholar
Maier SF, Watkins LR. Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. Neurosci Biobehav Rev. 2005;29:829–41.
Article CAS PubMed Google Scholar
Landgraf D, Long J, Der-Avakian A, Streets M, Welsh DK. Dissociation of learned helplessness and fear conditioning in mice: a mouse model of depression. PLoS One. 2015;10:e0125892.
Article PubMed PubMed Central Google Scholar
Greenwood BN, Strong PV, Fleshner M. Lesions of the basolateral amygdala reverse the long-lasting interference with shuttle box escape produced by uncontrollable stress. Behavioural Brain Res. 2010;211:71–6.
Root DH, Barker DJ, Estrin DJ, Miranda-Barrientos JA, Liu B, Zhang S, et al. Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior. Cell Rep. 2020;32:108094.
Article CAS PubMed PubMed Central Google Scholar
Root DH, Mejias-Aponte CA, Zhang S, Wang HL, Hoffman AF, Lupica CR, et al. Single rodent mesohabenular axons release glutamate and GABA. Nat Neurosci. 2014;17:1543–51.
Article CAS PubMed PubMed Central Google Scholar
Root DH, Zhang S, Barker DJ, Miranda-Barrientos J, Liu B, Wang HL, et al. Selective Brain Distribution and Distinctive Synaptic Architecture of Dual Glutamatergic-GABAergic Neurons. Cell Rep. 2018;23:3465–79.
Article CAS PubMed PubMed Central Google Scholar
McGovern DJ, Polter AM, Root DH. Neurochemical Signaling of Reward and Aversion to Ventral Tegmental Area Glutamate Neurons. J Neurosci. 2021;41:5471–86.
Article CAS PubMed PubMed Central Google Scholar
Shin LM, Liberzon I. The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology. 2010;35:169–91.
Kessler RC, Stang P, Wittchen HU, Stein M, Walters EE. Lifetime co-morbidities between social phobia and mood disorders in the US National Comorbidity Survey. Psychol Med. 1999;29:555–67.
Article CAS PubMed Google Scholar
Root DH, Estrin DJ, Morales M. Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons. iScience. 2018;2:51–62.
Article CAS PubMed PubMed Central Google Scholar
Qi J, Zhang S, Wang HL, Barker DJ, Miranda-Barrientos J, Morales M. VTA glutamatergic inputs to nucleus accumbens drive aversion by acting on GABAergic interneurons. Nat Neurosci. 2016;19:725–33.
Article CAS PubMed PubMed Central Google Scholar
Wang HL, Qi J, Zhang S, Wang H, Morales M. Rewarding Effects of Optical Stimulation of Ventral Tegmental Area Glutamatergic Neurons. J Neurosci. 2015;35:15948–54.
Article CAS PubMed PubMed Central Google Scholar
Gomez JL, Bonaventura J, Lesniak W, Mathews WB, Sysa-Shah P, Rodriguez LA, et al. Chemogenetics revealed: DREADD occupancy and activation via converted clozapine. Science. 2017;357:503–7.
Article CAS PubMed PubMed Central Google Scholar
Hnasko TS, Hjelmstad GO, Fields HL, Edwards RH. Ventral tegmental area glutamate neurons: electrophysiological properties and projections. J Neurosci. 2012;32:15076–85.
Article CAS PubMed PubMed Central Google Scholar
Miranda‐Barrientos J, Chambers I, Mongia S, Liu B, Wang HL, Mateo‐Semidey GE, et al. Ventral tegmental area GABA, glutamate, and glutamate‐GABA neurons are heterogeneous in their electrophysiological and pharmacological properties. Eur J Neurosci. 2021;54:4061–84.
Maier SF, Watkins LR. Role of the medial prefrontal cortex in coping and resilience. Brain Res. 2010;1355:52–60.
Article CAS PubMed PubMed Central Google Scholar
An XL, Zou JX, Wu RY, Yang Y, Tai FD, Zeng SY, et al. Strain and sex differences in anxiety-like and social behaviors in C57BL/6J and BALB/cJ mice. Exp Anim. 2011;60:111–23.
Article CAS PubMed Google Scholar
Berger S, Gureczny S, Reisinger SN, Horvath O, Pollak DD. Effect of Chronic Corticosterone Treatment on Depression-Like Behavior and Sociability in Female and Male C57BL/6N Mice. Cells 2019;8:1018.
Bondar NP, Lepeshko AA, Reshetnikov VV. Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects. Behav Neurol. 2018;2018:1538931.
Article PubMed PubMed Central Google Scholar
Karlsson SA, Haziri K, Hansson E, Kettunen P, Westberg L. Effects of sex and gonadectomy on social investigation and social recognition in mice. BMC Neurosci. 2015;16:83.
Article PubMed PubMed Central Google Scholar
Voikar V, Koks S, Vasar E, Rauvala H. Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies. Physiol Behav. 2001;72:271–81.
Article CAS PubMed Google Scholar
Rosso M, Wirz R, Loretan AV, Sutter NA, da Cunha CTP, Jaric I, et al. Reliability of Common Mouse Behavioural Tests of Anxiety: a Systematic Review and Meta-Analysis on the Effects of Anxiolytics. Neurosci Biobehav Rev. 2022:104928.
Mingote S, Chuhma N, Kalmbach A, Thomsen GM, Wang Y, Mihali A et al. Dopamine neuron dependent behaviors mediated by glutamate cotransmission. Elife 2017;6:e27566.
Graybuck LT, Daigle TL, Sedeño-Cortés AE, Walker M, Kalmbach B, Lenz GH. et al. Enhancer viruses for combinatorial cell-subclass-specific labeling. Neuron 2021;109:1449–.e641413.
Li D, Yang H, Xiong F, Xu X, Zeng WB, Zhao F et al. Anterograde Neuronal Circuit Tracers Derived from Herpes Simplex Virus 1: Development, Application, and Perspectives. Int J Mol Sci. 2020;21:5937.
Zeng WB, Jiang HF, Gang YD, Song YG, Shen ZZ, Yang H, et al. Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129. Mol Neurodegener. 2017;12:38.
Article PubMed PubMed Central Google Scholar
Garcia-Keller C, Kupchik YM, Gipson CD, Brown RM, Spencer S, Bollati F, et al. Glutamatergic mechanisms of comorbidity between acute stress and cocaine self-administration. Mol Psychiatry. 2016;21:1063–9.
Article CAS PubMed Google Scholar
Maier SF. Behavioral control blunts reactions to contemporaneous and future adverse events: medial prefrontal cortex plasticity and a corticostriatal network. Neurobiol Stress. 2015;1:12–22.
Amat J, Aleksejev RM, Paul E, Watkins LR, Maier SF. Behavioral control over shock blocks behavioral and neurochemical effects of later social defeat. Neuroscience. 2010;165:1031–8.
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