Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay

A549 cells

human non-small cell lung cancer cells

Hela cells

human cervical cancer cells

BEAS-2B

normal human lung epithelial cells

dppf

diphenylphosphino ferrocene

MMP

mitochondrial membrane potential

ROS

reactive oxygen species

Bcl-2

B cell CLL/lymphoma-2 protein

Caspase-3

cysteine aspartic acid specific protease-3

PARP

poly ADP-ribose polymerase

LCM

laser confocal microscopy

MTT

3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide

LTDR

lysosome fluorescent probe

MTDR

mitochondrial fluorescent probe

DAPI

2-(4-Amidinophenyl)-6-indolecarbamidine dihydrochloride

PCC

pearson's colocalization coefficient

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