HQIP. National Maternity and Perinatal Audit (NMPA) clinical report. 2019.
Poston L, Caleyachetty R, Cnattingius S, Corvalan C, Uauy R, Herring S, et al. Preconceptional and maternal obesity: epidemiology and health consequences. Lancet Diabetes Endocrinol. 2016;4:1025–36.
Heslehurst N. Identifying ‘at risk’ women and the impact of maternal obesity on National Health Service maternity services. Proc Nutr Soc. 2011;70:439–49.
Godfrey KM, Reynolds RM, Prescott SL, Nyirenda M, Jaddoe VW, Eriksson JG, et al. Influence of maternal obesity on the long-term health of offspring. Lancet Diabetes Endocrinol. 2017;5:53–64.
Patro Golab B, Santos S, Voerman E, Lawlor DA, Jaddoe VWV, Gaillard R, et al. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health. 2018;2:812–21.
Razaz N, Villamor E, Muraca GM, Bonamy AE, Cnattingius S. Maternal obesity and risk of cardiovascular diseases in offspring: a population-based cohort and sibling-controlled study. Lancet Diabetes Endocrinol. 2020;8:572–81.
Reynolds RM, Allan KM, Raja EA, Bhattacharya S, McNeill G, Hannaford PC, et al. Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years. BMJ. 2013;347:f4539.
PubMed PubMed Central Article Google Scholar
Sundholm JKM, Litwin L, Rono K, Koivusalo SB, Eriksson JG, Sarkola T. Maternal obesity and gestational diabetes: Impact on arterial wall layer thickness and stiffness in early childhood – RADIEL study six-year follow-up. Atherosclerosis. 2019;284:237–44.
CAS PubMed Article Google Scholar
Samuelsson AM, Matthews PA, Argenton M, Christie MR, McConnell JM, Jansen EH, et al. Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programming. Hypertension. 2008;51:383–92.
CAS PubMed Article Google Scholar
Samuelsson AM, Morris A, Igosheva N, Kirk SL, Pombo JMC, Coen CW, et al. Evidence for sympathetic origins of hypertension in juvenile offspring of obese rats. Hypertension. 2010;55:76–U129.
CAS PubMed Article Google Scholar
Fernandez-Twinn DS, Blackmore HL, Siggens L, Giussani DA, Cross CM, Foo R, et al. The programming of cardiac hypertrophy in the offspring by maternal obesity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation. Endocrinology. 2012;153:5961–71.
CAS PubMed PubMed Central Article Google Scholar
Samuelsson AS, Mullier A, Maicas N, Oosterhuis NR, Eun Bae S, Novoselova TV, et al. Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity. Proc Natl Acad Sci USA. 2016;113:12298–303.
CAS PubMed PubMed Central Article Google Scholar
Poston L, Bell R, Croker H, Flynn AC, Godfrey KM, Goff L, et al. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial. Lancet Diabetes Endocrinol. 2015;3:767–77.
Mills HL, Patel N, White SL, Pasupathy D, Briley AL, Santos Ferreira DL, et al. The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial. BMC Med. 2019;17:15.
PubMed PubMed Central Article Google Scholar
Patel N, Godfrey KM, Pasupathy D, Levin J, Flynn AC, Hayes L, et al. Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy. Int J Obes (Lond). 2017;41:1018–26.
Mat Husin H, Schleger F, Bauer I, Fehlert E, Kiefer-Schmidt I, Weiss M, et al. Maternal weight, weight gain, and metabolism are associated with changes in fetal heart rate and variability. Obesity (Silver Spring). 2020;28:114–21.
Daniels SR, Kimball TR, Morrison JA, Khoury P, Meyer RA. Indexing left ventricular mass to account for differences in body size in children and adolescents without cardiovascular disease. Am J Cardiol. 1995;76:699–701.
CAS PubMed Article Google Scholar
Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015;16:233–70.
de Simone G, Daniels SR, Devereux RB, Meyer RA, Roman MJ, de Divitiis O, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol. 1992;20:1251–60.
National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114:555–76.
Nunan D, Sandercock GR, Brodie DA. A quantitative systematic review of normal values for short-term heart rate variability in healthy adults. Pacing Clin Electrophysiol. 2010;33:1407–17.
Tarvainen MP, Niskanen JP, Lipponen JA, Ranta-Aho PO, Karjalainen PA. Kubios HRV-heart rate variability analysis software. Comput Methods Programs Biomed. 2014;113:210–20.
Tarvainen MP, Ranta-Aho PO, Karjalainen PA. An advanced detrending method with application to HRV analysis. IEEE Trans Biomed Eng. 2002;49:172–5.
Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology. 1990;1:43–6.
CAS PubMed Article Google Scholar
Althouse AD. Adjust for multiple comparisons? It’s not that simple. Ann Thorac Surg. 2016;101:1644–5.
Hershman DL, Unger JM, Greenlee H, Capodice JL, Lew DL, Darke AK, et al. Effect of acupuncture vs sham acupuncture or waitlist control on joint pain related to aromatase inhibitors among women with early-stage breast cancer: a randomized clinical trial. JAMA. 2018;320:167–76.
PubMed PubMed Central Article Google Scholar
Qian X, Loo BRY, Castellanos FX, Liu S, Koh HL, Poh XWW, et al. Brain-computer-interface-based intervention re-normalizes brain functional network topology in children with attention deficit/hyperactivity disorder. Transl Psychiatry. 2018;8:149.
PubMed PubMed Central Article Google Scholar
Gademan MG, van Eijsden M, Roseboom TJ, van der Post JA, Stronks K, Vrijkotte TG. Maternal prepregnancy body mass index and their children’s blood pressure and resting cardiac autonomic balance at age 5 to 6 years. Hypertension. 2013;62:641–7.
CAS PubMed Article Google Scholar
Gaillard R, Welten M, Oddy WH, Beilin LJ, Mori TA, Jaddoe VW, et al. Associations of maternal prepregnancy body mass index and gestational weight gain with cardio-metabolic risk factors in adolescent offspring: a prospective cohort study. BJOG. 2016;123:207–16.
CAS PubMed Article Google Scholar
Litwin L, Sundholm JKM, Rono K, Koivusalo SB, Eriksson JG, Sarkola T. Transgenerational effects of maternal obesity and gestational diabetes on offspring body composition and left ventricle mass: the Finnish Gestational Diabetes Prevention Study (RADIEL) 6-year follow-up. Diabet Med. 2020;37:147–56.
CAS PubMed Article Google Scholar
Geelhoed JJ, VAN Osch-Gevers L, Verburg BO, Steegers EA, Hofman A, Helbing W, et al. Maternal anthropometrics in pregnancy are associated with left ventricular mass in infancy. The generation R study. Pediatr Res. 2008;63:62–6.
Panagiotopoulou O, Syngelaki A, Georgiopoulos G, Simpson J, Akolekar R, Shehata H, et al. Metformin use in obese mothers is associated with improved cardiovascular profile in the offspring. Am J Obstet Gynecol. 2020;223:246 e1–e10.
Toemen L, Gishti O, van Osch-Gevers L, Steegers EA, Helbing WA, Felix JF, et al. Maternal obesity, gestational weight gain and childhood cardiac outcomes: role of childhood body mass index. Int J Obes (Lond). 2016;40:1070–8.
Patel N, Dalrymple KV, Briley AL, Pasupathy D, Seed PT, Flynn AC, et al. Mode of infant feeding, eating behaviour and anthropometry in infants at 6-months of age born to obese women – a secondary analysis of the UPBEAT trial. BMC Pregnancy Childbirth. 2018;18:355.
PubMed PubMed Central Article Google Scholar
Dalrymple KV, Tydeman FAS, Taylor PD, Flynn AC, O'Keeffe M, Briley AL, et al. Adiposity and cardiovascular outcomes in three-year-old children of participants in UPBEAT, an RCT of a complex intervention in pregnant women with obesity. Pediatr Obes. 2021;16:e12725.
Ingul CB, Loras L, Tegnander E, Eik-Nes SH, Brantberg A. Maternal obesity affects fetal myocardial function as early as in the first trimester. Ultrasound Obstet Gynecol. 2016;47:433–42.
CAS PubMed Article Google Scholar
Guzzardi MA, Liistro T, Gargani L, Ait Ali L, D’Angelo G, Rocchiccioli S, et al. Maternal obesity and cardiac development in the offspring: study in human neonates and minipigs. JACC Cardiovasc Imaging. 2018;11:1750–5.
Schieken RM, Schwartz PF, Goble MM. Tracking of left ventricular mass in children: race and sex comparisons: the MCV Twin Study. Medical College of Virginia. Circulation. 1998;97:1901–6.
CAS PubMed Article Google Scholar
Toemen L, Gaillard R, van Osch-Gevers L, Helbing WA, Hofman A, Jaddoe VW. Tracking of structural and functional cardiac measures from infancy into school-age. Eur J Prev Cardiol. 2017;24:1408–15.
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