circRERE regulates the expression of GBX2 through miR-1299 and ZC3H13/N6-methyladenosine (m6A) to promote growth and invasion of hepatocellular carcinoma cells

Cheng X, Li M, Rao X, et al. 2019 KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA. Onco. Targets Ther. 12 3421–3428

CAS  Article  Google Scholar 

Cristea CG, Gheonea IA, Săndulescu LD, et al. 2015 Considerations regarding current diagnosis and prognosis of hepatocellular carcinoma. J. Med. Life 8 120–128

CAS  PubMed  PubMed Central  Google Scholar 

Fang Y, Yuan Y, Zhang LL, et al. 2018 Downregulated GBX2 gene suppresses proliferation, invasion and angiogenesis of breast cancer cells through inhibiting the Wnt/β-catenin signaling pathway. Cancer Biomark. 23 405–418

CAS  Article  Google Scholar 

Fu LY, Wang SW, Hu MY, et al. 2021 Circular RNAs in liver diseases: Mechanisms and therapeutic targets. Life Sci. 264 118707

CAS  Article  Google Scholar 

Gao AC, Lou W and Isaacs JT 2000 Enhanced GBX2 expression stimulates growth of human prostate cancer cells via transcriptional up-regulation of the interleukin 6 gene. Clin. Cancer Res. 6 493–497

CAS  PubMed  Google Scholar 

Gong PJ, Shao YC, Yang Y, et al. 2020 Analysis of N6-methyladenosine methyltransferase reveals METTL14 and ZC3H13 as tumor suppressor genes in breast cancer. Front. Oncol. 10 578963

Article  Google Scholar 

Gong Y, Mao J, Wu D, et al. 2018 Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6. Cancer Cell Int. 18 116

Gu J, Zhan Y, Zhuo L, et al. 2021 Biological functions of m6A methyltransferases. Cell Biosci. 11 15

CAS  Article  Google Scholar 

Knuckles P, Lence T, Haussmann IU, et al. 2018 Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev. 32 415–429

CAS  Article  Google Scholar 

Li F, Wang H, Huang H, Zhang L, Wang D and Wan Y 2020 m6A RNA methylation regulators participate in the malignant progression and have clinical prognostic value in lung adenocarcinoma. Front. Genet. 11 994

CAS  Article  Google Scholar 

Liu LH, Tian QQ, Liu J, Zhou Y and Yong H 2019 Upregulation of hsa_circ_0136666 contributes to breast cancer progression by sponging miR-1299 and targeting CDK6. J. Cell Biochem. 120 12684–12693

CAS  Article  Google Scholar 

Marquardt JU, Andersen JB and Thorgeirsson SS 2015 Functional and genetic deconstruction of the cellular origin in liver cancer. Nat. Rev. Cancer 15 653–667

CAS  Article  Google Scholar 

Nombela P, Miguel-López B and Blanco S 2021 The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities. Mol. Cancer 20 18

CAS  Article  Google Scholar 

Sun JY, Zhang XY, Cao YZ, et al. 2020 Diagnostic and prognostic value of circular RNAs in hepatocellular carcinoma. J. Cell Mol. Med. 24 5438–5445

CAS  Article  Google Scholar 

Wang M, Yu F and Li P 2018 Circular RNAs: Characteristics, function and clinical significance in hepatocellular carcinoma. Cancers 10 258

Article  Google Scholar 

Wang M, Yang Y, Yang J, Yang J and Han S 2020a circ_KIAA1429 accelerates hepatocellular carcinoma advancement through the mechanism of m6A-YTHDF3-Zeb1. Life Sci. 257 118082

CAS  Article  Google Scholar 

Wang Y, Hui J, Li R, et al. 2020b GBX2, as a tumor promoter in lung adenocarcinoma, enhances cells viability, invasion and migration by regulating the AKT/ERK signaling pathway. J. Gene Med. 22 e3147

CAS  PubMed  Google Scholar 

Wen J, Lv R, Ma H, et al. 2018 Zc3h13 Regulates nuclear RNA m6A methylation and mouse embryonic stem cell self-renewal. Mol. Cell 69 1028-1038.e6

CAS  Article  Google Scholar 

Wu C, Deng L, Zhuo H, et al. 2020 Circulating circRNA predicting the occurrence of hepatocellular carcinoma in patients with HBV infection. J. Cell Mol. Med. 24 10216–10222

CAS  Article  Google Scholar 

Xia B, Zhao Z, Wu Y, et al. 2020 Circular RNA circTNPO3 Regulates paclitaxel resistance of ovarian cancer cells by miR-1299/NEK2 signaling pathway. Mol. Ther. Nucleic Acids 21 780–791

CAS  Article  Google Scholar 

Xu Y, Yao Y, Liu Y, et al. 2019 Elevation of circular RNA circ_0005230 facilitates cell growth and metastasis via sponging miR-1238 and miR-1299 in cholangiocarcinoma. Aging 11 1907–1917

CAS  Article  Google Scholar 

Zhang X, Xu Y, Qian Z, et al. 2018 circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 9 1091

Article  Google Scholar 

Zhang C, Huang S, Zhuang H, et al. 2020 YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation. Oncogene 39 4507–4518

CAS  Article  Google Scholar 

Zhu H, Wang G, Zhou X, et al. 2016 miR-1299 suppresses cell proliferation of hepatocellular carcinoma (HCC) by targeting CDK6. Biomed. Pharmacother. 83 792–797

Article  Google Scholar 

Zhu D, Zhou J, Zhao J, et al. 2019 ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling. J. Cell Physiol. 234 8899–8907

CAS  Article  Google Scholar 

留言 (0)

沒有登入
gif