Intermediate alleles of HTT: A new pathway in longevity

Gonos E.S.

Genetics of aging: lessons from centenarians.

Exp. Gerontol. 2000 Feb; 35 (PMID: 10705035): 15-21https://doi.org/10.1016/s0531-5565(99)00075-3View in Article PubMed Crossref Google ScholarMontesanto A. De Rango F. Pirazzini C. Guidarelli G. Domma F. Franceschi C. Passarino G.

Demographic, genetic and phenotypic characteristics of centenarians in Italy: focus on gender differences.

Mech. Ageing Dev. 2017 Jul; 165 (Epub 2017 Apr 29. PMID: 28461103): 68-74https://doi.org/10.1016/j.mad.2017.04.008View in Article Scopus (16) PubMed Crossref Google ScholarSantos-Lozano A. Santamarina A. Pareja-Galeano H. Sanchis-Gomar F. Fiuza-Luces C. Cristi-Montero C. Bernal-Pino A. Lucia A. Garatachea N.

The genetics of exceptional longevity: insights from centenarians.

Maturitas. 2016 Aug; 90 (Epub 2016 May 10. PMID: 27282794): 49-57https://doi.org/10.1016/j.maturitas.2016.05.006View in Article Scopus (20) PubMed Abstract Full Text Full Text PDF Google ScholarCaruso C. Passarino G. Puca A. Scapagnini G.

“Positive biology”: the centenarian lesson.

Immun. Ageing. 2012; 9 (Published 2012 Apr 23)5https://doi.org/10.1186/1742-4933-9-5View in Article Scopus (31) Crossref Google ScholarWillcox D.C. Willcox B.J. Hsueh W.C. Suzuki M.

Genetic determinants of exceptional human longevity: insights from the Okinawa Centenarian Study.

Age (Dordr.). 2006 Dec; 28 (Epub 2006 Dec 8. PMID: 22253498; PMCID: PMC3259160): 313-332https://doi.org/10.1007/s11357-006-9020-xView in Article Scopus (55) PubMed Crossref Google ScholarSebastiani P. Perls T.T.

The genetics of extreme longevity: lessons from the new England centenarian study.

Front. Genet. 2012 Nov 30; 3 (PMID: 23226160; PMCID: PMC3510428): 277https://doi.org/10.3389/fgene.2012.00277View in Article Scopus (117) PubMed Crossref Google ScholarGaragnani P. Marquis J. Delledonne M. Pirazzini C. Marasco E. Kwiatkowska K.M. Iannuzzi V. Bacalini M.G. Valsesia A. Carayol J. Raymond F. Ferrarini A. Xumerle L. Collino S. Mari D. Arosio B. Casati M. Ferri E. Monti D. Nacmias B. Sorbi S. Luiselli D. Pettener D. Castellani G. Sala C. Passarino G. De Rango F. D’Aquila P. Bertamini L. Martinelli N. Girelli D. Olivieri O. Giuliani C. Descombes P. Franceschi C.

Whole-genome sequencing analysis of semi-supercentenarians.

Elife. 2021 May 4; 10 (PMID: 33941312; PMCID: PMC8096429)e57849https://doi.org/10.7554/eLife.57849View in Article Scopus (10) PubMed Crossref Google ScholarBroer L. Buchman A.S. Deelen J. Evans D.S. Faul J.D. Lunetta K.L. Sebastiani P. Smith J.A. Smith A.V. Tanaka T. Yu L. Arnold A.M. Aspelund T. Benjamin E.J. De Jager P.L. Eirkisdottir G. Evans D.A. Garcia M.E. Hofman A. Kaplan R.C. Kardia S.L. Kiel D.P. Oostra B.A. Orwoll E.S. Parimi N. Psaty B.M. Rivadeneira F. Rotter J.I. Seshadri S. Singleton A. Tiemeier H. Uitterlinden A.G. Zhao W. Bandinelli S. Bennett D.A. Ferrucci L. Gudnason V. Harris T.B. Karasik D. Launer L.J. Perls T.T. Slagboom P.E. Tranah G.J. Weir D.R. Newman A.B. van Duijn C.M. Murabito J.M.

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.

J. Gerontol. A Biol. Sci. Med. Sci. 2015 Jan; 70 (Epub 2014 Sep 8. PMID: 25199915; PMCID: PMC4296168): 110-118https://doi.org/10.1093/gerona/glu166View in Article Scopus (177) PubMed Crossref Google ScholarDeelen J. Beekman M. Uh H.W. Broer L. Ayers K.L. Tan Q. Kamatani Y. Bennet A.M. Tamm R. Trompet S. Guðbjartsson D.F. Flachsbart F. Rose G. Viktorin A. Fischer K. Nygaard M. Cordell H.J. Crocco P. van den Akker E.B. Böhringer S. Helmer Q. Nelson C.P. Saunders G.I. Alver M. Andersen-Ranberg K. Breen M.E. van der Breggen R. Caliebe A. Capri M. Cevenini E. Collerton J.C. Dato S. Davies K. Ford I. Gampe J. Garagnani P. de Geus E.J. Harrow J. van Heemst D. Heijmans B.T. Heinsen F.A. Hottenga J.J. Hofman A. Jeune B. Jonsson P.V. Lathrop M. Lechner D. Martin-Ruiz C. Mcnerlan S.E. Mihailov E. Montesanto A. Mooijaart S.P. Murphy A. Nohr E.A. Paternoster L. Postmus I. Rivadeneira F. Ross O.A. Salvioli S. Sattar N. Schreiber S. Stefánsson H. Stott D.J. Tiemeier H. Uitterlinden A.G. Westendorp R.G. Willemsen G. Samani N.J. Galan P. Sørensen T.I. Boomsma D.I. Jukema J.W. Rea I.M. Passarino G. de Craen A.J. Christensen K. Nebel A. Stefánsson K. Metspalu A. Magnusson P. Blanché H. Christiansen L. Kirkwood T.B. van Duijn C.M. Franceschi C. Houwing-Duistermaat J.J. Slagboom P.E.

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum. Mol. Genet. 2014 Aug 15; 23 (Epub 2014 Mar 31. PMID: 24688116; PMCID: PMC4103672): 4420-4432https://doi.org/10.1093/hmg/ddu139View in Article Scopus (164) PubMed Crossref Google ScholarFortney K. Dobriban E. Garagnani P. Pirazzini C. Monti D. Mari D. Atzmon G. Barzilai N. Franceschi C. Owen A.B. Kim S.K.

Genome-wide scan informed by age-related disease identifies loci for exceptional human longevity.

PLoS Genet. 2015 Dec 17; 11 (PMID: 26677855; PMCID: PMC4683064)e1005728https://doi.org/10.1371/journal.pgen.1005728View in Article Scopus (84) PubMed Crossref Google ScholarPilling L.C. Atkins J.L. Bowman K. Jones S.E. Tyrrell J. Beaumont R.N. Ruth K.S. Tuke M.A. Yaghootkar H. Wood A.R. Freathy R.M. Murray A. Weedon M.N. Xue L. Lunetta K. Murabito J.M. Harries L.W. Robine J.M. Brayne C. Kuchel G.A. Ferrucci L. Frayling T.M. Melzer D.

Human longevity is influenced by many genetic variants: evidence from 75,000 UK biobank participants.

Aging (Albany NY). 2016 Mar; 8: 547-560https://doi.org/10.18632/aging.100930. PMID: 27015805; PMCID: PMC4833145View in Article PubMed Crossref Google ScholarSebastiani P. Bae H. Sun F.X. Andersen S.L. Daw E.W. Malovini A. Kojima T. Hirose N. Schupf N. Puca A. Perls T.T.

Meta-analysis of genetic variants associated with human exceptional longevity.

Aging (Albany NY). 2013 Sep; 5: 653-661https://doi.org/10.18632/aging.100594. PMID: 24244950; PMCID: PMC3808698View in Article PubMed Crossref Google ScholarSebastiani P. Gurinovich A. Bae H. Andersen S. Malovini A. Atzmon G. Villa F. Kraja A.T. Ben-Avraham D. Barzilai N. Puca A. Perls T.T.

Four genome-wide association studies identify new extreme longevity variants.

J. Gerontol. A Biol. Sci. Med. Sci. 2017 Oct 12; 72: 1453-1464https://doi.org/10.1093/gerona/glx027. PMID: 28329165; PMCID: PMC5861867View in Article Scopus (0) PubMed Crossref Google ScholarCellini E. Nacmias B. Olivieri F. Ortenzi L. Tedde A. Bagnoli S. Petruzzi C. Franceschi C. Sorbi S.

Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians.

Mech. Ageing Dev. 2005; 126 (Jun–Jul. (PMID: 15888337)): 826-828https://doi.org/10.1016/j.mad.2005.01.009View in Article Scopus (55) PubMed Crossref Google ScholarNacmias B. Bagnoli S. Tedde A. Cellini E. Bessi V. Guarnieri B. Ortensi L. Piacentini S. Bracco L. Sorbi S.

Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimer’s disease and longevity.

Arch. Gerontol. Geriatr. 2007 Sep-Oct; 45 (Epub 2006 Dec 19): 201-206https://doi.org/10.1016/j.archger.2006.10.01117182125View in Article Scopus (23) PubMed Crossref Google ScholarPiaceri I. Bagnoli S. Lucenteforte E. Mancuso M. Tedde A. Siciliano G. Piacentini S. Bracco L. Sorbi S. Nacmias B.

Implication of a genetic variant at PICALM in Alzheimer’s disease patients and centenarians.

J. Alzheimers Dis. 2011; 24 (PMID: 21297266): 409-413https://doi.org/10.3233/JAD-2011-101791View in Article Scopus (17) PubMed Crossref Google ScholarOrkin J.D. Montague M.J. Tejada-Martinez D. de Manuel M. Del Campo J. Cheves Hernandez S. Di Fiore A. Fontsere C. Hodgson J.A. Janiak M.C. Kuderna L.F.K. Lizano E. Martin M.P. Niimura Y. Perry G.H. Valverde C.S. Tang J. Warren W.C. de Magalhães J.P. Kawamura S. Marquès-Bonet T. Krawetz R. Melin A.D.

The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS.

Proc. Natl. Acad. Sci. U. S. A. 2021 Feb 16; 118 (Erratum in: Proc Natl Acad Sci U S A. 2021 Aug 24;118(34): PMID: 33574059; PMCID: PMC7896301)e2010632118https://doi.org/10.1073/pnas.2010632118View in Article Scopus (12) PubMed Crossref Google ScholarLi Y. de Magalhães J.P.

Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity.

Age (Dordr.). 2013 Apr; 35 (Epub 2011 Dec 29. PMID: 22205409; PMCID: PMC3592953): 301-314https://doi.org/10.1007/s11357-011-9361-yView in Article Scopus (42) PubMed Crossref Google ScholarTacutu R. Thornton D. Johnson E. Budovsky A. Barardo D. Craig T. Diana E. Lehmann G. Toren D. Wang J. Fraifeld V.E. de Magalhães J.P.

Human ageing genomic resources: new and updated databases.

Nucleic Acids Res. 2018 Jan 4; 46: D1083-D1090https://doi.org/10.1093/nar/gkx1042. PMID: 29121237; PMCID: PMC5753192View in Article Scopus (0) PubMed Crossref Google ScholarZheng S. Clabough E.B. Sarkar S. Futter M. Rubinsztein D.C. Zeitlin S.O.

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.

PLoS Genet. 2010; 6 (Published 2010 Feb 5): e1000838https://doi.org/10.1371/journal.pgen.1000838View in Article Scopus (124) PubMed Crossref Google Scholar

Chiu E. Huntington's disease. Burns A., Levy R. Dementia. Springer, Boston, MA. doi.1:0.1007/978-1-4615-6805-6_47.

View in Article Google ScholarDe Luca A. Morella A. Consoli F. Fanelli S. Thibert J.R. Statt S. Latham G.J. Squitieri F.

A novel triplet-primed PCR assay to detect the full range of trinucleotide CAG repeats in the huntingtin gene (HTT).

Int. J. Mol. Sci. 2021 Feb 8; 22 (PMID: 33567536; PMCID: PMC7916029): 1689https://doi.org/10.3390/ijms22041689View in Article Scopus (4) PubMed Crossref Google ScholarCubo E. Ramos-Arroyo M.A. Martinez-Horta S. Martínez-Descalls A. Calvo S. Gil-Polo C. European HD Network

Clinical manifestations of intermediate allele carriers in Huntington disease.

Neurology. 2016 Aug 9; 87 (Epub 2016 Jul 8. PMID: 27402890): 571-578https://doi.org/10.1212/WNL.0000000000002944View in Article Scopus (32) PubMed Crossref

留言 (0)

沒有登入
gif