Vascular response
Coronary reactive hyperemia
CYP450-enzymes
Soluble epoxide hydrolase
Adenosine receptors
Plasma/heart perfusate oxylipins
Abbreviations6-keto-PGF1α6-keto prostaglandin-F1α
A2AARA2A adenosine receptor
BKLarge conductance potassium channels
CRHcoronary reactive hyperemia
CYP450-2J2Cytochrome P450-2J2
DDMSdibromo-dodecenyl-methylsulfimide
DHETsdihydroxyeicosatrienoic acids
DiHOMEsdihydroxyoctadecaenoic acids
EDHFEndothelium-Derived Hyperpolarizing Factor
EETsEpoxyeicosatrienoic acids
EpOMEsepoxyoctadecaenoic acids
HETEshydroxyeicosatetraenoic acids
HODEshydroxyoctadecadienoic acids
KATPATP-sensitive K+ channels
KCaCalcium-acitvated K+ channels
LC-MS/MSliquid chromatography tandem mass spectroscopy
PUFAspolyunsaturated fatty acids
sEHsoluble epoxide hydrolase
sEH−/− or Ephx2−/−sEH–knockout mice
sEH+/+wild type mice normally expressing sEH
t-AUCBtrans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy] benzoic acid
A2AAR−/−A2AAR–knockout mice
A2AAR+/+wild type mice normally expressing A2AAR
A1ARA1 adenosine receptor
A1AR−/−A1AR–knockout mice
A1AR+/+wild type mice normally expressing A1AR
A2BARA2B adenosine receptor
A2BAR−/−A2BAR–knockout mice
A2BAR+/+wild type mice normally expressing A2BAR
CVDsCardiovascular diseases
CADcoronary artery disease
ADORA1adenosine A1 receptor gene
ADORA2adenosine A2A receptor gene
Tie2-sEH Tr micesEH-overexpressed mice
Tie2-CYP2J2 Tr miceCYP2J2-overexpressed mice
A3ARadenosine A3 receptor
PPARγperoxisome proliferator-activated receptor gamma
PPARαperoxisome proliferator-activated receptor alpha
SSI or acute ischemic preconditioningsublethal simulated ischemia
A1AR-tgmover-expression of adenosine A1 receptor in transgenic mice
DPCPX8-Cyclopentyl-1,3-dipropylxanthine
SHRspontaneously hypertensive rats
RAASrenin-angiotensin-aldosterone system
iPAHidiopathic pulmonary arterial hypertension
PAHpulmonary arterial hypertension
GPCRG-protein-coupled receptor
MSPPOHN-methylsulphonyl-6-(2-proparglyloxyphenyl) hexamide
14,15-EEZE14,15-Epoxyeicosa-5(Z)-enoic Acid
HET0016N-hydroxy-N_-(4-n-butyl-2-methylphenyl) formamidine
AR9281[1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea
AUDA12-(3-adamantane-1-yl-ureido) dodecanoic acid
BI00611953N-(2-chloro-4-methanesulfonyl-benzyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
CDU/NCND1-cyclohexyl-3-dodecyl-urea
TPPUN-[1-(1-oxopropyl)-4-piperidinyl]-N′-[4-(trifluoromethoxy)phenyl)-urea
AEPU1-adamantan-3-(5-(2-(2-ethylethoxy)ethoxy)pentyl) urea
DCUN,N′-dicyclohexylurea
GSK2256294((1R,3S)-N-(4-cyano-2-(trifluoromethyl)benzyl)-3- ((4-methyl-6-(methylamino)-1,3,5-triazin-2- yl)amino)cyclohexane-1-carboxamide)
GSK2188931B[N-(methyl)- 1-[4-methyl-6 (methylamino-1,3,5-triazin-2-yl]- 4-piperidinecarboxamide]
PTUPB[4-(5-phenyl-3--pyrazol-1-yl)-benzenesulfonamide]
t-CUPM[trans-5--pyridine-2 carboxylic acid methylamide
TPAU1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl) urea
TUPS1-(1-methanesulfonyl-piperidin-4-yl)-3- (4-trifluoromethoxy-phenyl)-urea
8-HUDE12-(3-hexylureido) dodec-8-enoic acid
NECA5’-N-Ethylcarboxamidoadenosine
CGS-216802-(4-(2-Carboxyethyl)phenethylamino)-5’-N-ethylcarboxamidoadenosine
CCPA2-Chloro-N6-cyclopentyladenosine
ZM2413854-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol
SCH-582612-(2-furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Chelerythrine chloride1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
Glibenclamide5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl) phenyl]ethyl]-2-methoxybenzamide
5-hydroxydecanoate5-hydroxydecanoic acid sodium salt
Rosiglitazone5-(4-methyl)-1,3-thiazolidine-2,4-dione
GW76472-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid
eNOS−/− miceendothelial nitric oxide synthase knockout mice.
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